ICD-10: A37.10

Whooping cough due to Bordetella parapertussis without pneumonia

Additional Information

Description

Whooping cough, clinically known as pertussis, is primarily caused by the bacterium Bordetella pertussis. However, it can also be caused by Bordetella parapertussis, which is less common and typically results in a milder form of the disease. The ICD-10 code A37.10 specifically refers to whooping cough due to Bordetella parapertussis without pneumonia, indicating a non-complicated case of this respiratory infection.

Clinical Description

Etiology

Bordetella parapertussis is a gram-negative bacterium that causes respiratory infections similar to those caused by Bordetella pertussis. While Bordetella pertussis is the primary agent responsible for classic whooping cough, Bordetella parapertussis can lead to a similar clinical presentation but is generally associated with a less severe illness.

Symptoms

The clinical presentation of whooping cough due to Bordetella parapertussis typically includes:

  • Coughing Fits: Characteristic paroxysmal coughing episodes that may be followed by a "whoop" sound, although this is less common with Bordetella parapertussis.
  • Cough Duration: The cough can persist for several weeks, often lasting up to 10 weeks or more.
  • Inspiratory Stridor: A high-pitched sound during inhalation may occur, especially in young children.
  • Post-tussive Vomiting: Coughing fits may lead to vomiting in some patients.
  • Mild Fever: Patients may experience a low-grade fever, but high fever is uncommon.

Diagnosis

Diagnosis of whooping cough due to Bordetella parapertussis is typically made through:

  • Clinical Evaluation: Assessment of symptoms and patient history.
  • Laboratory Testing: PCR (Polymerase Chain Reaction) testing can confirm the presence of Bordetella parapertussis in respiratory specimens. Serological tests may also be used, although they are less specific.

Treatment

Management of whooping cough caused by Bordetella parapertussis generally includes:

  • Antibiotics: Macrolides (such as azithromycin) are commonly prescribed to reduce the duration of symptoms and prevent transmission.
  • Supportive Care: This may include hydration, cough suppressants, and monitoring for complications, especially in young children.

Complications

While the ICD-10 code A37.10 specifies cases without pneumonia, it is important to note that complications can still arise, including:

  • Secondary Infections: Such as otitis media (ear infections).
  • Dehydration: Resulting from severe coughing or vomiting.
  • Sleep Disturbances: Due to persistent coughing.

Conclusion

ICD-10 code A37.10 captures the clinical essence of whooping cough due to Bordetella parapertussis without pneumonia, highlighting the importance of accurate diagnosis and management. Understanding the nuances of this condition is crucial for healthcare providers to ensure appropriate treatment and to mitigate the risk of complications, particularly in vulnerable populations such as infants and young children.

Clinical Information

Whooping cough, clinically known as pertussis, is primarily caused by the bacterium Bordetella pertussis; however, it can also be caused by Bordetella parapertussis, which is less common. The ICD-10 code A37.10 specifically refers to whooping cough due to Bordetella parapertussis without pneumonia. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for accurate diagnosis and management.

Clinical Presentation

Overview

Whooping cough due to Bordetella parapertussis typically presents with a series of characteristic symptoms that evolve over time. The disease is known for its prolonged cough, which can be particularly distressing for patients.

Stages of Whooping Cough

The clinical presentation of whooping cough can be divided into three stages:

  1. Catarrhal Stage (1-2 weeks):
    - Symptoms resemble those of a common cold, including:

    • Runny nose (rhinorrhea)
    • Mild cough
    • Low-grade fever
    • Sneezing
    • This stage is often overlooked as it mimics viral upper respiratory infections.
  2. Paroxysmal Stage (2-6 weeks):
    - Characterized by severe coughing fits (paroxysms) that can lead to:

    • A "whooping" sound during inhalation after a coughing fit
    • Vomiting after coughing
    • Exhaustion following coughing episodes
    • Coughing fits may occur multiple times a day and can be triggered by various stimuli, including laughing, crying, or physical activity.
  3. Convalescent Stage (weeks to months):
    - Gradual recovery occurs, with a decrease in the frequency and severity of cough.
    - Cough may persist for several weeks, even after other symptoms have resolved.

Signs and Symptoms

Common Symptoms

  • Cough: The hallmark symptom, often described as a series of rapid coughs followed by a high-pitched "whoop."
  • Cyanosis: A bluish discoloration of the skin, particularly around the lips and face, may occur during severe coughing fits.
  • Apnea: In infants, episodes of apnea (pauses in breathing) can occur, which is a serious concern.
  • Post-tussive vomiting: Vomiting may occur after intense coughing episodes.

Additional Symptoms

  • Fatigue: Patients often feel extremely tired due to the effort of coughing.
  • Sleep disturbances: Coughing can disrupt sleep, leading to further fatigue and irritability.

Patient Characteristics

Demographics

  • Age: Whooping cough can affect individuals of all ages, but it is particularly severe in infants and young children. Adults may also be affected, often with milder symptoms.
  • Vaccination Status: Patients who are unvaccinated or under-vaccinated are at higher risk for developing whooping cough. The DTaP vaccine is recommended for children, while Tdap is recommended for adolescents and adults.

Risk Factors

  • Close Contact: Individuals in close contact with infected persons are at increased risk.
  • Immunocompromised Status: Patients with weakened immune systems may experience more severe symptoms.
  • Chronic Respiratory Conditions: Those with pre-existing respiratory issues may have exacerbated symptoms.

Conclusion

Whooping cough due to Bordetella parapertussis without pneumonia presents a unique clinical picture characterized by a distinct cough pattern and stages of illness. Recognizing the signs and symptoms early, particularly in vulnerable populations such as infants, is essential for timely intervention and management. Vaccination remains a critical preventive measure to reduce the incidence of this disease. Understanding these clinical aspects can aid healthcare providers in diagnosing and treating patients effectively, ensuring better health outcomes.

Approximate Synonyms

The ICD-10 code A37.10 specifically refers to "Whooping cough due to Bordetella parapertussis without pneumonia." This code is part of a broader classification system used for diagnosing and coding various diseases and conditions. Below are alternative names and related terms associated with this specific code.

Alternative Names for A37.10

  1. Parapertussis: This term directly refers to the infection caused by Bordetella parapertussis, distinguishing it from the more common Bordetella pertussis, which causes classic whooping cough.

  2. Bordetella Parapertussis Infection: This name emphasizes the causative agent of the infection, highlighting the specific bacterium responsible for the condition.

  3. Whooping Cough (Parapertussis): This term combines the common name for the disease with the specific type of Bordetella involved, clarifying that it is a variant of whooping cough.

  4. Non-Pneumonic Whooping Cough: This phrase indicates that the infection does not involve pneumonia, which is a critical distinction in clinical settings.

  1. Bordetella Species: Refers to the genus of bacteria that includes both Bordetella pertussis and Bordetella parapertussis, relevant for understanding the broader context of whooping cough.

  2. Cough Illness: A general term that can encompass various types of cough-related diseases, including whooping cough.

  3. Respiratory Tract Infection: A broader category that includes infections affecting the respiratory system, of which whooping cough is a specific example.

  4. Vaccine-Preventable Diseases: Whooping cough is included in this category, as vaccines are available to prevent infections caused by Bordetella pertussis and Bordetella parapertussis.

  5. Chronic Cough: While not specific to whooping cough, this term can relate to the prolonged cough that may occur in cases of Bordetella infections.

  6. Pertussis-Like Illness: This term may be used to describe illnesses that present symptoms similar to those of whooping cough but are caused by different pathogens.

Understanding these alternative names and related terms can be beneficial for healthcare professionals when diagnosing, coding, and discussing cases of whooping cough due to Bordetella parapertussis. It also aids in differentiating between the various types of whooping cough and their respective causative agents.

Diagnostic Criteria

The diagnosis of whooping cough due to Bordetella parapertussis, classified under ICD-10 code A37.10, involves several criteria that healthcare professionals utilize to ensure accurate identification of the condition. Below is a detailed overview of the diagnostic criteria and considerations for this specific code.

Clinical Presentation

Symptoms

The primary symptoms of whooping cough include:

  • Paroxysmal Coughing: Characterized by severe, uncontrollable coughing fits that can lead to a "whooping" sound when the patient inhales.
  • Cough Duration: The cough typically lasts for weeks, often persisting for more than three weeks.
  • Inspiratory Whoop: Although not always present, the classic whooping sound is a hallmark of the disease, particularly in children.
  • Post-tussive Vomiting: Coughing fits may be followed by vomiting, especially in younger patients.

Age Considerations

While whooping cough can affect individuals of any age, infants and young children are particularly vulnerable. Adults may also experience atypical presentations, which can complicate diagnosis.

Laboratory Testing

Microbiological Confirmation

To confirm a diagnosis of whooping cough due to Bordetella parapertussis, laboratory tests may be employed:

  • Polymerase Chain Reaction (PCR): This is the most sensitive and specific test for detecting Bordetella parapertussis DNA in nasopharyngeal swabs. PCR testing is particularly useful in the early stages of the illness.
  • Culture: Although less commonly used due to its lower sensitivity, culturing the bacteria from a nasopharyngeal specimen can provide definitive identification.

Serological Testing

Serological tests for antibodies against Bordetella species may also be utilized, but they are generally less reliable for acute diagnosis compared to PCR.

Exclusion of Other Conditions

Differential Diagnosis

It is crucial to differentiate whooping cough from other respiratory illnesses, such as:

  • Bacterial Pneumonia: The presence of pneumonia would necessitate a different ICD-10 code (A37.9 for whooping cough with pneumonia).
  • Viral Infections: Conditions like RSV or influenza can present with similar symptoms but require different management strategies.

Clinical History

A thorough clinical history, including vaccination status (e.g., DTaP or Tdap), exposure history, and symptom onset, is essential for accurate diagnosis.

Conclusion

In summary, the diagnosis of whooping cough due to Bordetella parapertussis without pneumonia (ICD-10 code A37.10) relies on a combination of clinical symptoms, laboratory testing (primarily PCR), and the exclusion of other respiratory conditions. Accurate diagnosis is critical for effective management and treatment, particularly in vulnerable populations such as infants and young children. If you have further questions or need additional information, feel free to ask!

Treatment Guidelines

Whooping cough, clinically known as pertussis, is primarily caused by the bacterium Bordetella pertussis, but it can also be caused by Bordetella parapertussis. The ICD-10 code A37.10 specifically refers to whooping cough due to Bordetella parapertussis without pneumonia. Understanding the standard treatment approaches for this condition is crucial for effective management and patient care.

Overview of Whooping Cough

Whooping cough is characterized by severe coughing fits that can lead to difficulty breathing, vomiting, and exhaustion. The cough is often followed by a high-pitched "whoop" sound, especially in children. While Bordetella pertussis is the more common cause, Bordetella parapertussis can also lead to similar symptoms, albeit typically with a milder presentation[1].

Standard Treatment Approaches

1. Antibiotic Therapy

Antibiotics are the cornerstone of treatment for whooping cough, particularly in the early stages of the disease. The following antibiotics are commonly prescribed:

  • Azithromycin: This is often the first-line treatment due to its efficacy and favorable dosing schedule.
  • Clarithromycin: Another macrolide antibiotic that can be used as an alternative.
  • Trimethoprim-sulfamethoxazole: This is an alternative for patients who are allergic to macrolides, although it is less commonly used in young children due to potential side effects[2][3].

The primary goal of antibiotic therapy is to reduce the severity and duration of symptoms, prevent the spread of the infection, and minimize complications.

2. Supportive Care

Supportive care is essential in managing symptoms and ensuring patient comfort. This may include:

  • Hydration: Ensuring adequate fluid intake to prevent dehydration, especially in young children who may vomit due to coughing fits.
  • Nutritional Support: Small, frequent meals may be recommended to help maintain nutrition without triggering coughing.
  • Humidified Air: Using a humidifier can help soothe irritated airways and ease coughing.

3. Monitoring and Follow-Up

Patients diagnosed with whooping cough should be closely monitored for complications, especially in infants and young children. Follow-up visits may be necessary to assess recovery and manage any persistent symptoms, such as prolonged cough or difficulty breathing[4].

4. Vaccination

While vaccination is not a treatment for active infection, it is crucial for prevention. The DTaP (diphtheria, tetanus, and pertussis) vaccine is recommended for children, and Tdap (tetanus, diphtheria, and pertussis) booster shots are advised for adolescents and adults. Vaccination helps reduce the incidence of whooping cough and its associated complications[5].

Conclusion

In summary, the standard treatment for whooping cough due to Bordetella parapertussis without pneumonia primarily involves antibiotic therapy, supportive care, and careful monitoring. Vaccination plays a vital role in prevention, helping to reduce the overall burden of this infectious disease. Early diagnosis and treatment are key to managing symptoms effectively and preventing complications, particularly in vulnerable populations such as infants and young children. If you suspect whooping cough, it is essential to seek medical attention promptly to initiate appropriate care.

Related Information

Description

  • Caused by *Bordetella parapertussis* bacterium
  • Similar symptoms to whooping cough caused by *Bordetella pertussis*
  • Typically less severe than classic whooping cough
  • Characterized by persistent coughing fits and 'whoop' sound
  • May include inspiratory stridor, post-tussive vomiting, and mild fever
  • Diagnosed through clinical evaluation and PCR testing
  • Treated with macrolide antibiotics and supportive care

Clinical Information

  • Whooping cough caused by Bordetella parapertussis
  • Prolonged cough with distressing symptoms
  • Three stages: Catarrhal, Paroxysmal, and Convalescent
  • Common symptoms include runny nose, mild cough, low-grade fever, sneezing, and exhaustion
  • Coughing fits can lead to cyanosis, apnea in infants, post-tussive vomiting, fatigue, and sleep disturbances
  • Whooping cough affects individuals of all ages but is severe in infants and young children
  • Unvaccinated or under-vaccinated patients are at higher risk for developing whooping cough

Approximate Synonyms

  • Parapertussis
  • Bordetella Parapertussis Infection
  • Whooping Cough (Parapertussis)
  • Non-Pneumonic Whooping Cough
  • Bordetella Species
  • Cough Illness
  • Respiratory Tract Infection

Diagnostic Criteria

  • Severe, uncontrollable coughing fits
  • Cough lasting more than three weeks
  • Inspiratory whoop sound in patients
  • Post-tussive vomiting common in children
  • PCR testing for Bordetella parapertussis DNA
  • Culture of bacteria from nasopharyngeal specimen
  • Exclusion of bacterial pneumonia and viral infections

Treatment Guidelines

  • Antibiotics reduce symptom severity
  • Azithromycin is first-line treatment
  • Clarithromycin alternative for macrolide allergy
  • Trimethoprim-sulfamethoxazole for allergic patients
  • Hydrate to prevent dehydration
  • Nutritional support through small meals
  • Humidified air soothes irritated airways

Related Diseases

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