ICD-10: B17.10

Acute hepatitis C without hepatic coma

Clinical Information

Inclusion Terms

  • Acute hepatitis C NOS

Additional Information

Description

Acute hepatitis C is a viral infection that primarily affects the liver, caused by the hepatitis C virus (HCV). The ICD-10 code B17.10 specifically refers to acute hepatitis C without hepatic coma, indicating a recent infection that has not progressed to severe liver failure or coma.

Clinical Description

Definition

Acute hepatitis C is characterized by the sudden onset of liver inflammation due to the hepatitis C virus. This condition can manifest within weeks to months after exposure to the virus, often through blood-to-blood contact, such as sharing needles or receiving contaminated blood products.

Symptoms

Patients with acute hepatitis C may experience a range of symptoms, which can vary in severity. Common symptoms include:
- Fatigue: A general feeling of tiredness or lack of energy.
- Jaundice: Yellowing of the skin and eyes due to elevated bilirubin levels.
- Dark Urine: Urine may appear darker than usual, often resembling tea or cola.
- Pale Stools: Stools may become lighter in color.
- Abdominal Pain: Discomfort or pain in the upper right quadrant of the abdomen.
- Nausea and Vomiting: Some patients may experience gastrointestinal symptoms.

Diagnosis

Diagnosis of acute hepatitis C typically involves:
- Serological Tests: Detection of antibodies to HCV (anti-HCV) and HCV RNA in the blood. The presence of HCV RNA indicates an active infection.
- Liver Function Tests: Blood tests to assess liver enzyme levels (ALT, AST) which are often elevated during infection.
- Imaging Studies: Ultrasound may be used to evaluate liver size and structure, although it is not routinely necessary for diagnosis.

Complications

While many individuals may recover from acute hepatitis C without treatment, some may develop chronic hepatitis C, which can lead to long-term liver damage, cirrhosis, or liver cancer. The risk of progression to chronic infection is significant, with estimates suggesting that approximately 55% to 85% of those infected will develop chronic hepatitis C[1].

Treatment

Treatment for acute hepatitis C may not always be necessary, as many patients clear the virus spontaneously. However, antiviral therapy may be recommended in certain cases, particularly for those with severe symptoms or at high risk of developing chronic infection. Direct-acting antiviral agents (DAAs) are the standard treatment, offering high cure rates with relatively few side effects.

Conclusion

ICD-10 code B17.10 is crucial for accurately documenting cases of acute hepatitis C without hepatic coma. Understanding the clinical presentation, diagnostic criteria, and potential complications associated with this condition is essential for effective management and treatment. Early detection and intervention can significantly improve patient outcomes and reduce the risk of chronic liver disease.


[1] Centers for Disease Control and Prevention (CDC) - Hepatitis C FAQs for Health Professionals.

Diagnostic Criteria

Acute hepatitis C, classified under ICD-10 code B17.10, is a viral infection characterized by inflammation of the liver due to the hepatitis C virus (HCV). The diagnosis of acute hepatitis C involves several criteria and considerations, which are essential for accurate identification and management of the condition.

Diagnostic Criteria for Acute Hepatitis C

1. Clinical Presentation

  • Symptoms: Patients may present with symptoms such as fatigue, jaundice (yellowing of the skin and eyes), dark urine, pale stools, abdominal pain, and loss of appetite. However, many individuals may be asymptomatic during the acute phase[1].
  • History of Exposure: A thorough patient history is crucial, including potential exposure to HCV through intravenous drug use, blood transfusions, or sexual contact with an infected individual[2].

2. Laboratory Testing

  • Serological Tests: The diagnosis is confirmed through serological tests that detect antibodies to HCV (anti-HCV). In acute hepatitis C, these antibodies may not be present immediately after infection, so testing should be repeated if initial results are negative but clinical suspicion remains high[3].
  • HCV RNA Testing: The presence of HCV RNA in the blood is a definitive indicator of active infection. This test can detect the virus earlier than antibody tests and is crucial for confirming acute hepatitis C[4].
  • Liver Function Tests: Elevated levels of liver enzymes (ALT and AST) are indicative of liver inflammation and damage. In acute hepatitis C, these enzymes are typically significantly elevated[5].

3. Exclusion of Other Causes

  • It is essential to rule out other causes of hepatitis, such as hepatitis A, B, D, E, and other non-viral causes (e.g., alcohol, medications, autoimmune diseases). This may involve additional serological tests and patient history assessment[6].

4. Clinical Guidelines

  • Following established clinical guidelines, such as those from the Centers for Disease Control and Prevention (CDC) and the American Association for the Study of Liver Diseases (AASLD), can aid in the diagnosis and management of acute hepatitis C. These guidelines recommend specific testing protocols and follow-up procedures for suspected cases[7].

Conclusion

The diagnosis of acute hepatitis C (ICD-10 code B17.10) relies on a combination of clinical evaluation, serological and molecular testing, and exclusion of other liver disease causes. Early diagnosis is crucial for effective management and to prevent the progression to chronic hepatitis C, which can lead to severe liver complications. If you suspect acute hepatitis C, it is advisable to consult healthcare professionals for appropriate testing and management strategies.

Clinical Information

Acute hepatitis C, classified under ICD-10 code B17.10, is a viral infection that primarily affects the liver. Understanding its clinical presentation, signs, symptoms, and patient characteristics is crucial for timely diagnosis and management.

Clinical Presentation

Acute hepatitis C typically manifests within 2 to 12 weeks after exposure to the hepatitis C virus (HCV). The clinical presentation can vary significantly among individuals, with some experiencing mild symptoms while others may have more severe manifestations.

Signs and Symptoms

The symptoms of acute hepatitis C can be nonspecific and may include:

  • Fatigue: A common symptom that can range from mild to severe, often leading to decreased activity levels.
  • Jaundice: Yellowing of the skin and eyes due to elevated bilirubin levels, indicating liver dysfunction.
  • Dark Urine: A result of bilirubin excretion in urine, often accompanying jaundice.
  • Pale Stools: Light-colored stools may occur due to a lack of bile reaching the intestines.
  • Nausea and Vomiting: Gastrointestinal symptoms are prevalent and can lead to decreased appetite.
  • Abdominal Pain: Discomfort or pain in the upper right quadrant of the abdomen, where the liver is located.
  • Fever: A mild fever may be present, although it is not always observed.
  • Joint and Muscle Pain: Some patients report myalgia or arthralgia, contributing to overall discomfort.

Asymptomatic Cases

It is important to note that a significant number of individuals with acute hepatitis C may remain asymptomatic, which can lead to underdiagnosis. Studies suggest that approximately 20-30% of those infected may not exhibit any symptoms during the acute phase[1][2].

Patient Characteristics

Certain demographic and clinical characteristics can influence the presentation and outcomes of acute hepatitis C:

  • Age: Younger individuals, particularly those under 30, may have a higher likelihood of experiencing acute symptoms compared to older adults[3].
  • Gender: Some studies indicate that males may be more likely to develop symptomatic acute hepatitis C than females[4].
  • Co-infections: Patients co-infected with other viruses, such as HIV or hepatitis B, may experience more severe symptoms and complications[5].
  • Substance Use: Intravenous drug users are at a higher risk for acute hepatitis C due to shared needles, and they may present with more severe liver disease[6].
  • Comorbidities: Individuals with pre-existing liver conditions or other health issues may have a more complicated clinical course[7].

Conclusion

Acute hepatitis C without hepatic coma (ICD-10 code B17.10) presents a range of clinical symptoms that can vary widely among patients. Recognizing the signs and symptoms, along with understanding patient characteristics, is essential for healthcare providers to facilitate early diagnosis and appropriate management. Given the potential for asymptomatic cases, routine screening in high-risk populations is recommended to prevent long-term complications associated with chronic hepatitis C infection.


References

  1. Clinical Signs and Symptoms of Hepatitis C - CDC.
  2. Hepatitis C Clinical Presentation: History, Physical Examination - Medscape.
  3. Hepatitis C Prevalence and Birth Outcomes among ...
  4. Mortality Among Patients With Chronic Hepatitis B Infection.
  5. Technical Report: Acute Hepatitis of Unknown Cause.
  6. Hepatitis of unknown etiology in children in Brazil.
  7. ICD-10-CM Diagnosis Code B17.10 - Acute hepatitis C without hepatic coma.

Approximate Synonyms

ICD-10 code B17.10 refers specifically to "Acute hepatitis C without hepatic coma." This code is part of the broader classification of hepatitis C within the ICD-10 coding system, which is used for diagnosing and billing purposes in healthcare settings. Below are alternative names and related terms associated with this code:

Alternative Names

  1. Acute Hepatitis C: This is the most straightforward alternative name, emphasizing the acute nature of the infection.
  2. Acute Hepatitis C Virus Infection: This term highlights the viral cause of the hepatitis.
  3. Acute Hepatitis C Infection: Similar to the above, this term is often used interchangeably in clinical settings.
  1. Hepatitis C: A general term that encompasses all forms of hepatitis C, including acute and chronic stages.
  2. Viral Hepatitis: A broader category that includes hepatitis caused by various viruses, including hepatitis A, B, C, D, and E.
  3. Hepatitis C Serology: Refers to blood tests that detect antibodies or the virus itself, which are crucial for diagnosing acute hepatitis C.
  4. Acute Viral Hepatitis: A term that can refer to any viral hepatitis, but in the context of B17.10, it specifically pertains to hepatitis C.
  5. Non-comatose Hepatitis C: This term emphasizes the absence of hepatic coma, which is a severe complication of liver disease.

Clinical Context

Understanding these alternative names and related terms is essential for healthcare professionals when documenting patient diagnoses, coding for insurance purposes, and communicating effectively within the medical community. Accurate coding ensures proper treatment and management of the condition, as well as appropriate reimbursement for healthcare services provided.

In summary, ICD-10 code B17.10 is primarily known as "Acute hepatitis C without hepatic coma," but it is also referred to by several alternative names and related terms that reflect its clinical significance and context.

Treatment Guidelines

Acute hepatitis C, classified under ICD-10 code B17.10, refers to a recent infection with the hepatitis C virus (HCV) that has not progressed to hepatic coma. The management of this condition focuses on supportive care, monitoring, and, in some cases, antiviral therapy. Here’s a detailed overview of the standard treatment approaches for acute hepatitis C.

Understanding Acute Hepatitis C

Acute hepatitis C is typically characterized by the sudden onset of symptoms such as fatigue, jaundice, abdominal pain, and elevated liver enzymes. The infection is often asymptomatic, and many individuals may not realize they have contracted the virus until routine blood tests reveal elevated liver function tests or positive HCV antibodies[1].

Initial Assessment and Diagnosis

Upon suspicion of acute hepatitis C, healthcare providers will conduct a thorough assessment, which includes:

  • History and Physical Examination: Evaluating symptoms and potential exposure risks.
  • Laboratory Tests: Confirmatory tests include HCV RNA testing to detect the virus and serological tests for HCV antibodies. Elevated liver enzymes (ALT and AST) are also monitored[2].

Treatment Approaches

1. Supportive Care

Most patients with acute hepatitis C do not require specific antiviral treatment, as many will clear the virus spontaneously within six months. Supportive care includes:

  • Rest and Hydration: Encouraging adequate fluid intake and rest to help the body recover.
  • Nutritional Support: A balanced diet to support liver health, avoiding alcohol and hepatotoxic substances[3].

2. Monitoring

Regular follow-up is crucial to monitor liver function and the progression of the disease. Key aspects include:

  • Liver Function Tests: Monitoring ALT, AST, and bilirubin levels to assess liver health.
  • HCV RNA Testing: To determine if the virus is still present and to evaluate the likelihood of spontaneous viral clearance[4].

3. Antiviral Therapy

While most cases resolve spontaneously, antiviral treatment may be considered in certain situations, particularly for patients at high risk of developing chronic hepatitis C or those with severe symptoms. Current antiviral options include:

  • Direct-Acting Antivirals (DAAs): Medications such as sofosbuvir, ledipasvir, and velpatasvir have shown efficacy in treating acute hepatitis C. Treatment regimens typically last 8 to 12 weeks, depending on the specific DAA used and patient factors[5].
  • Interferon-Based Therapy: Historically, interferon was used, but it is now less common due to the side effects and the effectiveness of DAAs[6].

4. Patient Education and Counseling

Educating patients about the nature of the disease, transmission risks, and the importance of follow-up care is essential. Counseling may also include:

  • Preventive Measures: Advising on avoiding sharing needles, safe sex practices, and regular medical check-ups.
  • Support Resources: Connecting patients with support groups or counseling services if needed[7].

Conclusion

The management of acute hepatitis C (ICD-10 code B17.10) primarily involves supportive care and monitoring, with antiviral therapy reserved for specific cases. Most patients will recover without the need for aggressive treatment, but ongoing assessment is vital to ensure the best outcomes. As research continues, treatment protocols may evolve, emphasizing the importance of staying informed about the latest guidelines and recommendations in hepatitis C management.

Related Information

Description

  • Viral infection primarily affecting the liver
  • Caused by hepatitis C virus (HCV)
  • Recent infection without severe liver failure or coma
  • Sudden onset of liver inflammation due to HCV
  • Manifests within weeks to months after exposure
  • Common symptoms include fatigue, jaundice, dark urine and pale stools

Diagnostic Criteria

  • Patients present with fatigue and jaundice
  • History of HCV exposure essential
  • Serological tests detect anti-HCV antibodies
  • HCV RNA testing confirms active infection
  • Liver enzymes (ALT, AST) significantly elevated
  • Rule out other causes of hepatitis
  • Follow clinical guidelines for diagnosis

Clinical Information

  • Acute hepatitis C manifests within 2 to 12 weeks
  • Jaundice is yellowing of skin and eyes
  • Dark urine occurs due to bilirubin excretion
  • Pale stools are light-colored due to bile absence
  • Nausea and vomiting are prevalent gastrointestinal symptoms
  • Abdominal pain occurs in upper right abdomen
  • Fever is mild or absent symptom
  • Joint and muscle pain contributes to discomfort
  • Age influences likelihood of experiencing acute symptoms
  • Males may be more likely than females to develop symptomatic HCV
  • Co-infections with HIV or hepatitis B increase severity
  • Substance use via shared needles increases risk and severity

Approximate Synonyms

  • Acute Hepatitis C
  • Hepatitis C
  • Viral Hepatitis
  • Acute Viral Hepatitis
  • Non-comatose Hepatitis C
  • Acute Hepatitis C Virus Infection
  • Acute Hepatitis C Infection

Treatment Guidelines

  • Supportive care with rest and hydration
  • Nutritional support for liver health
  • Regular liver function tests monitoring
  • HCV RNA testing for virus presence
  • Antiviral therapy with DAAs (8-12 weeks)
  • Interferon-based therapy reserved for specific cases
  • Patient education on disease transmission and prevention

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.