ICD-10: B73.02
Onchocerciasis with glaucoma
Additional Information
Description
Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm Onchocerca volvulus. This condition is primarily transmitted through the bite of infected blackflies, which breed near fast-flowing rivers and streams. The disease is endemic in several regions, particularly in parts of Africa, Central America, and the Arabian Peninsula.
Clinical Description of Onchocerciasis
Symptoms and Manifestations
Onchocerciasis can lead to a variety of symptoms, primarily affecting the skin and eyes. The clinical manifestations include:
- Dermatological Symptoms: Patients often experience severe itching, rashes, and skin lesions, which can lead to secondary infections. The skin may become thickened and discolored, a condition known as "lizard skin" due to the presence of adult worms and their larvae in the skin.
- Ocular Symptoms: The most severe complication of onchocerciasis is ocular disease, which can lead to vision impairment and blindness. The infection can cause inflammation of the eye, leading to conditions such as keratitis, uveitis, and ultimately glaucoma. Glaucoma in this context is often a result of the inflammatory processes and damage to the optic nerve.
Pathophysiology
The pathophysiology of onchocerciasis involves the immune response to the adult worms and their microfilariae. The presence of these parasites triggers a chronic inflammatory response, which can lead to tissue damage and the aforementioned ocular complications. The inflammation can obstruct the drainage of aqueous humor in the eye, resulting in increased intraocular pressure and glaucoma.
ICD-10 Code B73.02: Onchocerciasis with Glaucoma
Code Details
The ICD-10 code B73.02 specifically refers to "Onchocerciasis with glaucoma." This classification indicates that the patient has been diagnosed with onchocerciasis and is experiencing glaucoma as a complication of the disease.
Clinical Implications
- Diagnosis: Accurate diagnosis typically involves a combination of clinical evaluation, patient history, and laboratory tests, including skin snips or serological tests to detect the presence of Onchocerca volvulus.
- Management: Treatment for onchocerciasis primarily includes the use of ivermectin, which is effective in reducing the microfilarial load and alleviating symptoms. However, management of glaucoma may require additional interventions, such as medications to lower intraocular pressure or surgical procedures if vision is severely compromised.
Prognosis
The prognosis for patients with onchocerciasis and glaucoma can vary significantly. Early diagnosis and treatment of onchocerciasis can prevent severe complications, including blindness. However, once glaucoma has developed, the risk of permanent vision loss increases, necessitating prompt and effective management.
In summary, ICD-10 code B73.02 encapsulates the serious implications of onchocerciasis when it leads to glaucoma, highlighting the need for comprehensive care that addresses both the parasitic infection and its ocular complications.
Clinical Information
Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm Onchocerca volvulus. The ICD-10 code B73.02 specifically refers to cases of onchocerciasis that are complicated by glaucoma. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for effective diagnosis and management.
Clinical Presentation
Overview of Onchocerciasis
Onchocerciasis is primarily transmitted through the bite of infected blackflies, which breed near fast-flowing rivers. The disease is endemic in several regions, particularly in sub-Saharan Africa, parts of Central and South America, and Yemen. The infection can lead to severe skin and eye complications, including glaucoma, which is a significant cause of visual impairment and blindness in affected populations[1][2].
Signs and Symptoms
The clinical manifestations of onchocerciasis can be categorized into skin and ocular symptoms:
Skin Symptoms
- Rashes and Itching: Patients often experience intense itching and rashes, which can lead to skin lesions and secondary infections.
- Lichenification: Chronic scratching may result in thickened, leathery skin.
- Nodules: Subcutaneous nodules, known as onchocercomas, may develop, particularly on the scalp, back, and limbs.
Ocular Symptoms
- Visual Disturbances: Patients may report blurred vision, decreased visual acuity, or complete loss of vision.
- Glaucoma: The presence of glaucoma in onchocerciasis patients is characterized by increased intraocular pressure, leading to optic nerve damage. Symptoms may include:
- Eye pain
- Headaches
- Halos around lights
- Redness of the eye
- Corneal Opacity: In advanced cases, corneal scarring can occur, contributing to blindness.
Patient Characteristics
Patients with onchocerciasis and glaucoma often share certain demographic and epidemiological characteristics:
- Geographic Distribution: Most cases are found in endemic regions, particularly in rural areas near rivers in Africa and some parts of Latin America.
- Age: The disease can affect individuals of all ages, but adults are more commonly affected due to prolonged exposure to blackfly bites.
- Gender: Males may be at higher risk due to occupational exposure, such as farming or fishing, which often takes place near rivers.
- Socioeconomic Factors: Individuals from lower socioeconomic backgrounds may have limited access to healthcare, increasing the risk of complications like glaucoma due to delayed diagnosis and treatment.
Conclusion
Onchocerciasis with glaucoma (ICD-10 code B73.02) presents a significant public health challenge, particularly in endemic regions. The clinical presentation includes a range of skin and ocular symptoms, with glaucoma being a severe complication that can lead to blindness. Understanding the signs, symptoms, and patient characteristics is essential for healthcare providers to facilitate early diagnosis and appropriate management, ultimately reducing the burden of this debilitating disease[3][4].
For effective management, it is crucial to implement preventive measures against blackfly bites and ensure access to treatment options, such as ivermectin, which can help control the infection and its complications.
Approximate Synonyms
Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm Onchocerca volvulus. The ICD-10 code B73.02 specifically refers to cases of onchocerciasis that are associated with glaucoma. Understanding alternative names and related terms for this condition can enhance clarity in medical documentation and communication.
Alternative Names for Onchocerciasis with Glaucoma
- River Blindness with Glaucoma: This term emphasizes the primary symptom of onchocerciasis, which is visual impairment, often leading to blindness.
- Onchocerciasis-Associated Glaucoma: This phrase highlights the relationship between the parasitic infection and the development of glaucoma.
- Onchocerciasis with Ocular Complications: This broader term can include various eye-related issues stemming from onchocerciasis, including glaucoma.
- Filarial Glaucoma: This term refers to glaucoma that arises as a complication of filarial infections, including onchocerciasis.
Related Terms
- Onchocerciasis: The base term for the disease caused by Onchocerca volvulus, which can lead to various complications, including glaucoma.
- Glaucoma: A group of eye conditions that damage the optic nerve, often associated with increased intraocular pressure, which can occur in patients with onchocerciasis.
- Ocular Onchocerciasis: This term refers to the eye-related manifestations of onchocerciasis, which can include inflammation and damage to ocular structures.
- Filarial Infection: A general term for infections caused by filarial worms, which includes onchocerciasis and can lead to various complications, including those affecting the eyes.
Conclusion
Understanding the alternative names and related terms for ICD-10 code B73.02 is crucial for healthcare professionals involved in diagnosing and treating onchocerciasis with glaucoma. This knowledge aids in accurate documentation and enhances communication among medical practitioners, ensuring that patients receive appropriate care for this complex condition.
Diagnostic Criteria
Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm Onchocerca volvulus. The ICD-10 code B73.02 specifically refers to cases of onchocerciasis that are associated with glaucoma. Diagnosing this condition involves several criteria and considerations, which can be categorized into clinical, laboratory, and imaging assessments.
Clinical Criteria
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Symptoms of Onchocerciasis:
- Patients may present with symptoms such as severe itching, skin rashes, and nodules (known as onchocercomas) under the skin. These symptoms are indicative of the infection caused by the Onchocerca volvulus worm. -
Ocular Symptoms:
- The presence of ocular symptoms is critical for diagnosing onchocerciasis with glaucoma. Symptoms may include:- Decreased vision or blindness
- Eye pain
- Photophobia (sensitivity to light)
- Redness and inflammation of the eye
-
History of Exposure:
- A history of living in or traveling to endemic areas where blackflies (the vectors for the parasite) are prevalent can support the diagnosis. This is particularly relevant in regions of Africa and parts of South America.
Laboratory Criteria
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Serological Tests:
- Serological tests can detect antibodies against Onchocerca volvulus. These tests help confirm the presence of the infection. -
Microfilariae Detection:
- The presence of microfilariae in skin snips or other tissue samples can be directly observed under a microscope. Skin snips are often taken from areas where the skin is most likely to harbor the larvae. -
PCR Testing:
- Polymerase chain reaction (PCR) tests can be used to detect the DNA of Onchocerca volvulus, providing a more sensitive method for confirming the infection.
Imaging Criteria
-
Ocular Examination:
- A comprehensive eye examination by an ophthalmologist is essential. This may include:- Fundoscopy to assess the retina and optic nerve for signs of damage or inflammation.
- Measurement of intraocular pressure to diagnose glaucoma.
-
Ultrasound or Other Imaging Techniques:
- In some cases, ultrasound may be used to visualize the eye structures and assess for any abnormalities associated with glaucoma.
Conclusion
The diagnosis of onchocerciasis with glaucoma (ICD-10 code B73.02) requires a multifaceted approach that includes clinical evaluation, laboratory testing, and imaging studies. The combination of these criteria helps healthcare providers confirm the diagnosis and differentiate it from other causes of glaucoma. Early diagnosis and treatment are crucial to prevent irreversible vision loss associated with this condition. If you have further questions or need more specific information, feel free to ask!
Treatment Guidelines
Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm Onchocerca volvulus. The condition is transmitted through the bite of infected blackflies and can lead to severe ocular complications, including glaucoma, as indicated by the ICD-10 code B73.02. This code specifically refers to cases of onchocerciasis that are associated with glaucoma, highlighting the need for targeted treatment approaches.
Overview of Onchocerciasis
Onchocerciasis is endemic in several regions, particularly in sub-Saharan Africa, parts of Central and South America, and Yemen. The disease can cause a range of symptoms, including severe itching, skin lesions, and eye problems that may lead to blindness. The presence of glaucoma in patients with onchocerciasis complicates the clinical picture, necessitating a multifaceted treatment approach.
Standard Treatment Approaches
1. Antiparasitic Treatment
The primary treatment for onchocerciasis is the administration of antiparasitic medications. The World Health Organization (WHO) recommends the following:
- Ivermectin: This is the first-line treatment for onchocerciasis. Ivermectin is effective in killing the microfilariae (larval stage) of the Onchocerca volvulus worm, thereby reducing the transmission of the disease. It is typically administered as a single oral dose once or twice a year, depending on the endemicity of the disease in the region[1][2].
2. Management of Glaucoma
Patients with onchocerciasis who develop glaucoma require specific interventions to manage intraocular pressure and prevent vision loss:
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Topical Medications: Prostaglandin analogs, beta-blockers, and carbonic anhydrase inhibitors are commonly used to lower intraocular pressure. These medications can be prescribed based on the severity of the glaucoma and the patient's overall health status[3].
-
Surgical Interventions: In cases where medical management is insufficient, surgical options such as trabeculectomy or the implantation of glaucoma drainage devices may be considered. These procedures aim to create a new drainage pathway for aqueous humor, thereby reducing intraocular pressure[4].
3. Supportive Care and Monitoring
Regular follow-up and monitoring are crucial for patients with onchocerciasis and glaucoma. This includes:
-
Ophthalmic Examinations: Regular eye exams are essential to assess the progression of glaucoma and the overall health of the eyes. This may involve visual field testing and optical coherence tomography (OCT) to monitor changes in the optic nerve[5].
-
Patient Education: Educating patients about the importance of adhering to treatment regimens and recognizing symptoms of worsening glaucoma is vital for preserving vision.
4. Community Health Initiatives
In endemic areas, community health initiatives play a significant role in controlling onchocerciasis. These initiatives may include:
-
Mass Drug Administration (MDA): Implementing MDA programs with ivermectin can significantly reduce the prevalence of onchocerciasis in communities, thereby decreasing the incidence of associated complications like glaucoma[6].
-
Health Education: Raising awareness about the disease, its transmission, and the importance of treatment can empower communities to seek timely medical care.
Conclusion
The management of onchocerciasis with glaucoma (ICD-10 code B73.02) requires a comprehensive approach that includes antiparasitic treatment, effective glaucoma management, and ongoing monitoring. By integrating these strategies, healthcare providers can improve patient outcomes and reduce the burden of this debilitating disease. Continued efforts in community health education and mass drug administration are essential to control the spread of onchocerciasis and its associated complications.
Related Information
Description
- Parasitic disease caused by Onchocerca volvulus
- Primarily transmitted through blackfly bites
- Affects skin and eyes with severe itching and rashes
- Can lead to vision impairment and blindness
- Glaucoma is a common complication of onchocerciasis
- Inflammation causes tissue damage and increased intraocular pressure
- Accurate diagnosis involves clinical evaluation and laboratory tests
Clinical Information
- Primarily transmitted through infected blackfly bites
- Common in sub-Saharan Africa, Central America, South America, and Yemen
- Severe skin and eye complications including glaucoma
- Glaucoma leads to visual impairment and blindness
- Skin symptoms: rashes, itching, lichenification, nodules
- Ocular symptoms: visual disturbances, increased intraocular pressure, optic nerve damage
- Corneal opacity and scarring in advanced cases
- Prolonged exposure to blackfly bites increases risk
- Males at higher risk due to occupational exposure
- Socioeconomic factors contribute to delayed diagnosis and treatment
Approximate Synonyms
- River Blindness with Glaucoma
- Onchocerciasis-Associated Glaucoma
- Onchocerciasis with Ocular Complications
- Filarial Glaucoma
- Ocular Onchocerciasis
Diagnostic Criteria
- Severe itching and skin rashes
- Decreased vision or blindness
- Eye pain and photophobia
- Redness and inflammation of the eye
- History of exposure in endemic areas
- Presence of microfilariae in skin snips
- Detection of antibodies against Onchocerca volvulus
- PCR testing for DNA of Onchocerca volvulus
- Fundoscopy to assess retina and optic nerve
- Measurement of intraocular pressure
Treatment Guidelines
- Administer Ivermectin as first-line treatment
- Manage glaucoma with topical medications
- Consider surgical interventions for uncontrolled glaucoma
- Monitor intraocular pressure with regular exams
- Educate patients on disease management and symptoms
- Implement mass drug administration in endemic areas
- Raise community awareness about disease transmission
Related Diseases
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