ICD-10: B74.9

Filariasis, unspecified

Additional Information

Description

Filariasis is a parasitic disease caused by filarial worms, which are transmitted to humans through the bites of infected mosquitoes. The ICD-10 code B74.9 specifically refers to Filariasis, unspecified, indicating a diagnosis of filariasis without further specification regarding the type of filarial infection or its clinical manifestations.

Clinical Description of Filariasis

Etiology

Filariasis is primarily caused by three types of filarial worms:
- Wuchereria bancrofti: The most common cause of lymphatic filariasis, prevalent in tropical and subtropical regions.
- Brugia malayi: Another cause of lymphatic filariasis, mainly found in Southeast Asia.
- Onchocerca volvulus: Responsible for river blindness (onchocerciasis), transmitted by blackflies.

Transmission

The transmission of filariasis occurs through the bite of infected mosquitoes, which introduce the larvae into the human bloodstream. The larvae then migrate to the lymphatic system, where they mature into adult worms.

Clinical Manifestations

The clinical presentation of filariasis can vary widely, and symptoms may not appear until years after infection. Common manifestations include:

  • Lymphatic Filariasis: Characterized by swelling of the limbs (lymphedema) and genitalia (hydrocele). Chronic infections can lead to severe disfigurement and disability.
  • Onchocerciasis: Symptoms include severe itching, skin rashes, and potential vision loss due to damage to the eyes.
  • Acute Filariasis: Patients may experience fever, lymphadenopathy, and pain in the affected areas.

Diagnosis

Diagnosis of filariasis typically involves:
- Clinical Evaluation: Assessment of symptoms and patient history, including travel to endemic areas.
- Laboratory Tests: Detection of microfilariae in blood samples, skin snips, or tissue biopsies. Serological tests may also be used to identify specific antibodies.

Treatment

Treatment for filariasis varies based on the type and severity of the infection:
- Lymphatic Filariasis: Management may include diethylcarbamazine (DEC) and supportive care for lymphedema.
- Onchocerciasis: Ivermectin is the primary treatment, effective in reducing microfilariae and alleviating symptoms.

Conclusion

The ICD-10 code B74.9 for filariasis, unspecified, encompasses a range of clinical presentations associated with filarial infections. Accurate diagnosis and treatment are crucial for managing the disease and preventing complications. Given the potential for significant morbidity associated with filariasis, awareness and early intervention are essential in endemic regions.

Clinical Information

Filariasis, classified under ICD-10 code B74.9, refers to a group of diseases caused by parasitic worms known as filariae. This condition is often transmitted through mosquito bites and can lead to various clinical manifestations depending on the specific type of filarial infection. Below is a detailed overview of the clinical presentation, signs, symptoms, and patient characteristics associated with unspecified filariasis.

Clinical Presentation

Filariasis can present in several forms, primarily depending on the species of the filarial worm involved. The most common types include:

  • Lymphatic Filariasis: Caused by Wuchereria bancrofti, Brugia malayi, or Brugia timori, this form primarily affects the lymphatic system.
  • Subcutaneous Filariasis: Often caused by Loa loa, this type affects the skin and subcutaneous tissues.
  • Serous Cavity Filariasis: Involves the serous cavities, such as the peritoneal cavity.

Signs and Symptoms

The symptoms of filariasis can vary widely, but common signs and symptoms include:

  • Lymphatic Filariasis:
  • Lymphedema: Swelling of the limbs, particularly the legs, due to lymphatic obstruction.
  • Elephantiasis: Severe swelling and thickening of the skin, often affecting the legs and genitalia.
  • Hydrocele: Accumulation of fluid in the scrotum, leading to swelling.
  • Fever and Chills: Acute episodes may present with fever, chills, and pain in the affected areas.

  • Subcutaneous Filariasis:

  • Calabar Swellings: Painful, localized swellings that can occur in various parts of the body.
  • Migrating Worms: Visible movement of the adult worms under the skin, particularly in cases of Loa loa.

  • Serous Cavity Filariasis:

  • Abdominal Pain: Discomfort or pain in the abdominal region due to fluid accumulation.

Patient Characteristics

Certain demographic and geographic factors can influence the prevalence and presentation of filariasis:

  • Geographic Distribution: Filariasis is endemic in tropical and subtropical regions, particularly in parts of Africa, Asia, the Pacific Islands, and some areas of the Americas.
  • Age: While filariasis can affect individuals of any age, children and young adults may be more susceptible to severe manifestations due to their developing immune systems.
  • Gender: Males are often more affected by lymphatic filariasis, particularly in regions where hydrocele is common.
  • Socioeconomic Factors: Individuals in lower socioeconomic conditions may have a higher risk due to limited access to healthcare, preventive measures, and education about mosquito control.

Conclusion

Filariasis, classified under ICD-10 code B74.9, presents a range of clinical manifestations that can significantly impact the quality of life of affected individuals. The disease's signs and symptoms vary based on the type of filarial infection, with lymphatic filariasis being the most common form. Understanding the clinical presentation and patient characteristics is crucial for effective diagnosis and management. Early detection and treatment can help mitigate the severe complications associated with this neglected tropical disease.

Approximate Synonyms

Filariasis, classified under ICD-10 code B74.9, refers to a parasitic disease caused by filarial worms, which are transmitted to humans through mosquito bites. The unspecified designation indicates that the specific type of filariasis is not identified. Here are some alternative names and related terms associated with this condition:

Alternative Names for Filariasis

  1. Lymphatic Filariasis: This is the most common form of filariasis, often leading to lymphedema and elephantiasis. It is caused primarily by Wuchereria bancrofti.

  2. Onchocerciasis: Also known as river blindness, this is caused by Onchocerca volvulus and is transmitted by blackflies. While not classified under B74.9, it is related to filarial infections.

  3. Loiasis: Caused by Loa loa, this type of filariasis is transmitted by the deer fly and can lead to eye-related symptoms.

  4. Bancroftian Filariasis: Specifically refers to the filariasis caused by Wuchereria bancrofti, which is the most prevalent type globally.

  5. Brugia Malayi Infection: This refers to filariasis caused by Brugia malayi, which is prevalent in Southeast Asia and can also lead to lymphatic complications.

  1. Filarial Infection: A broader term that encompasses all infections caused by filarial worms, including those not specifically classified under B74.9.

  2. Elephantiasis: A severe manifestation of lymphatic filariasis characterized by extreme swelling of body parts, particularly the legs and genitals.

  3. Lymphedema: A condition often resulting from lymphatic filariasis, where lymph fluid accumulates due to obstruction of lymphatic vessels.

  4. Parasitic Disease: A general term that includes filariasis as it is caused by parasitic organisms.

  5. Vector-borne Disease: Filariasis is transmitted through vectors (mosquitoes), making it part of this broader category of diseases.

  6. Chronic Filariasis: Refers to the long-term effects and complications arising from untreated filarial infections.

Conclusion

Understanding the alternative names and related terms for ICD-10 code B74.9 is crucial for accurate diagnosis, treatment, and communication among healthcare professionals. Filariasis encompasses various forms and related conditions, highlighting the importance of recognizing the specific type of filarial infection for effective management. If you need further information on specific types of filariasis or related conditions, feel free to ask!

Diagnostic Criteria

Filariasis is a parasitic disease caused by filarial worms, which are transmitted to humans through the bites of infected mosquitoes. The ICD-10 code B74.9 specifically refers to "Filariasis, unspecified," indicating a diagnosis of filariasis without further specification of the type or severity of the infection.

Diagnostic Criteria for Filariasis (ICD-10 Code B74.9)

The diagnosis of filariasis, including unspecified cases, typically involves a combination of clinical evaluation, laboratory tests, and epidemiological factors. Here are the key criteria used for diagnosis:

1. Clinical Symptoms

  • Lymphatic Filariasis: Patients may present with symptoms such as lymphedema, elephantiasis, and hydrocele. These symptoms arise from the obstruction of lymphatic vessels due to adult worms.
  • Subcutaneous Filariasis: Symptoms may include localized swelling, pain, and the presence of nodules under the skin.
  • Other Symptoms: Fever, chills, and general malaise may also be present, particularly during acute episodes.

2. Epidemiological History

  • Geographic Exposure: A history of travel or residence in endemic areas where filariasis is prevalent is crucial. This includes regions in tropical and subtropical climates, particularly in parts of Africa, Asia, and the Pacific Islands.
  • Mosquito Bites: Evidence of exposure to mosquito vectors known to transmit filarial infections, such as Culex and Anopheles species.

3. Laboratory Tests

  • Microfilaria Detection: The presence of microfilariae in blood samples is a definitive diagnostic criterion. This can be done through:
    • Blood Smear: A thick or thin blood smear can be examined under a microscope.
    • Filtration Techniques: Concentration techniques may be used to enhance detection.
  • Serological Tests: Tests that detect antibodies or antigens related to filarial infections can support the diagnosis, especially in cases where microfilariae are not detectable.
  • Imaging Studies: Ultrasound or other imaging modalities may be used to visualize lymphatic obstruction or other complications associated with filariasis.

4. Differential Diagnosis

  • It is essential to rule out other conditions that may present with similar symptoms, such as other parasitic infections, bacterial infections, or non-infectious causes of lymphedema.

Conclusion

The diagnosis of filariasis, particularly under the ICD-10 code B74.9, relies on a comprehensive approach that includes clinical evaluation, patient history, laboratory testing, and consideration of the epidemiological context. Accurate diagnosis is crucial for effective management and treatment of the disease, which may include antiparasitic medications and supportive care for complications. If you suspect filariasis, it is advisable to consult healthcare professionals who can perform the necessary evaluations and tests.

Treatment Guidelines

Filariasis, classified under ICD-10 code B74.9, refers to a parasitic infection caused by filarial worms, which are transmitted to humans through mosquito bites. The unspecified designation indicates that the specific type of filariasis is not identified, which can include lymphatic filariasis, onchocerciasis (river blindness), and others. Here’s a detailed overview of the standard treatment approaches for this condition.

Overview of Filariasis

Filariasis is primarily caused by three types of filarial worms:
- Wuchereria bancrofti: Responsible for lymphatic filariasis, leading to lymphedema and hydrocele.
- Brugia malayi: Also causes lymphatic filariasis, particularly in Southeast Asia.
- Onchocerca volvulus: Causes river blindness, leading to severe ocular complications.

The treatment for filariasis varies depending on the type of infection and the severity of symptoms.

Standard Treatment Approaches

1. Antiparasitic Medications

The cornerstone of treatment for filariasis involves antiparasitic drugs. The following medications are commonly used:

  • Diethylcarbamazine (DEC): This is the primary drug used for treating lymphatic filariasis. It works by killing the adult worms and microfilariae. DEC is typically administered in a single dose or over a few days, depending on the severity of the infection[1].

  • Ivermectin: This drug is particularly effective against Onchocerca volvulus and is often used in mass drug administration programs in endemic areas. It helps reduce the microfilarial load and alleviates symptoms associated with river blindness[2].

  • Albendazole: Often used in combination with DEC or ivermectin, albendazole helps enhance the efficacy of treatment by targeting the adult worms[3].

2. Symptomatic Treatment

Patients with filariasis may experience various symptoms, including lymphedema, pain, and secondary infections. Symptomatic treatment may include:

  • Pain Management: Non-steroidal anti-inflammatory drugs (NSAIDs) can be used to relieve pain and inflammation associated with lymphedema.

  • Management of Lymphedema: This includes physical therapy, compression bandaging, and hygiene measures to prevent secondary infections. Patients are often educated on self-care techniques to manage swelling and prevent complications[4].

  • Surgical Interventions: In cases of severe lymphedema or hydrocele, surgical options may be considered to remove excess tissue or fluid accumulation[5].

3. Preventive Measures

Preventive strategies are crucial in controlling filariasis, especially in endemic regions. These include:

  • Vector Control: Reducing mosquito populations through insecticide spraying, use of bed nets, and environmental management to eliminate breeding sites.

  • Mass Drug Administration (MDA): In areas where filariasis is endemic, MDA programs are implemented to treat entire populations, thereby reducing transmission rates. This typically involves administering DEC and albendazole to at-risk populations[6].

  • Health Education: Educating communities about the transmission of filariasis and the importance of preventive measures can significantly reduce infection rates.

Conclusion

The treatment of filariasis, particularly for unspecified cases under ICD-10 code B74.9, involves a combination of antiparasitic medications, symptomatic care, and preventive strategies. Early diagnosis and treatment are essential to prevent complications and improve patient outcomes. Public health initiatives focusing on vector control and mass drug administration play a critical role in managing and reducing the incidence of filariasis in endemic regions. For individuals diagnosed with filariasis, a comprehensive approach that includes medical treatment and lifestyle modifications is vital for effective management and recovery.


References

  1. Diethylcarbamazine (DEC) for lymphatic filariasis treatment.
  2. Ivermectin's role in treating Onchocerca volvulus.
  3. Albendazole as an adjunct therapy in filariasis.
  4. Management strategies for lymphedema in filariasis patients.
  5. Surgical options for severe filariasis complications.
  6. Importance of mass drug administration in filariasis control.

Related Information

Description

  • Caused by three types of filarial worms
  • Primarily transmitted through mosquito bites
  • Varied symptoms including lymphedema and hydrocele
  • Diagnosed by clinical evaluation and laboratory tests
  • Treated with diethylcarbamazine or ivermectin

Clinical Information

  • Lymphedema causes swelling of the limbs
  • Elephantiasis leads to severe skin thickening
  • Hydrocele involves fluid accumulation in scrotum
  • Fever and chills occur with acute episodes
  • Calabar swellings are painful localized swellings
  • Migrating worms move under the skin visibly
  • Abdominal pain due to fluid accumulation
  • Filariasis is endemic in tropical and subtropical regions
  • Children and young adults are more susceptible
  • Males are often affected by lymphatic filariasis

Approximate Synonyms

  • Lymphatic Filariasis
  • Onchocerciasis
  • Loiasis
  • Bancroftian Filariasis
  • Brugia Malayi Infection
  • Filarial Infection
  • Elephantiasis
  • Lymphedema
  • Parasitic Disease
  • Vector-borne Disease
  • Chronic Filariasis

Diagnostic Criteria

  • Lymphatic obstruction due to adult worms
  • Localized swelling and pain under skin
  • Fever, chills during acute episodes
  • History of travel to endemic areas
  • Exposure to mosquito vectors
  • Presence of microfilariae in blood
  • Serological tests positive for filarial antibodies

Treatment Guidelines

  • Diethylcarbamazine kills adult worms and microfilariae
  • Ivermectin reduces microfilarial load and alleviates river blindness symptoms
  • Albendazole enhances treatment efficacy by targeting adult worms
  • Pain Management: Use NSAIDs for lymphedema pain relief
  • Management of Lymphedema: Physical therapy, compression bandaging, hygiene measures
  • Surgical Interventions: Remove excess tissue or fluid accumulation in severe cases
  • Vector Control: Reduce mosquito populations through insecticide spraying and bed nets
  • Mass Drug Administration: Administer DEC and albendazole to at-risk populations

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.