ICD-10: C79.60

Secondary malignant neoplasm of unspecified ovary

Additional Information

Approximate Synonyms

The ICD-10 code C79.60 refers to a secondary malignant neoplasm of an unspecified ovary. This code is part of the broader classification of neoplasms, specifically focusing on secondary cancers that have metastasized to the ovaries from other primary sites. Below are alternative names and related terms associated with this code.

Alternative Names

  1. Metastatic Ovarian Cancer: This term is commonly used to describe cancer that has spread to the ovaries from another part of the body.
  2. Secondary Ovarian Tumor: This phrase emphasizes the tumor's nature as a secondary growth rather than a primary ovarian cancer.
  3. Ovarian Metastasis: This term specifically refers to the presence of cancer cells in the ovaries that originated from a primary tumor elsewhere in the body.
  1. ICD-10 Code C79.61: This code specifies a secondary malignant neoplasm of the right ovary, providing a more precise classification when the affected ovary is known.
  2. ICD-10 Code C79.62: This code indicates a secondary malignant neoplasm of the left ovary, similar to C79.61 but for the opposite side.
  3. ICD-O (International Classification of Diseases for Oncology): This classification system provides additional coding for neoplasms, including histological types and behavior of tumors, which can be relevant for understanding secondary ovarian neoplasms.
  4. Neoplasm of Uncertain Behavior: While not specific to secondary neoplasms, this term can sometimes be used in the context of tumors that do not have a clear primary origin.

Clinical Context

Secondary malignant neoplasms of the ovaries are often associated with various primary cancers, including breast, colorectal, and lung cancers. Understanding the terminology and coding related to these conditions is crucial for accurate diagnosis, treatment planning, and billing purposes in healthcare settings.

In summary, the ICD-10 code C79.60 encompasses various alternative names and related terms that reflect the nature of secondary malignant neoplasms affecting the ovaries. These terms are essential for healthcare professionals in accurately documenting and managing patient care.

Description

The ICD-10 code C79.60 refers to a secondary malignant neoplasm of unspecified ovary. This code is used in medical coding to classify cases where cancer has metastasized to the ovaries from another primary site, but the specific ovary affected is not identified. Below is a detailed clinical description and relevant information regarding this diagnosis.

Clinical Description

Definition

A secondary malignant neoplasm occurs when cancer cells spread from their original (primary) site to another part of the body. In the case of C79.60, the neoplasm has metastasized to the ovaries, which are part of the female reproductive system. This condition is significant as it indicates advanced disease and often correlates with a poorer prognosis.

Common Primary Sites

The most common primary cancers that can lead to secondary malignant neoplasms in the ovaries include:
- Breast Cancer: Often spreads to the ovaries, particularly in advanced stages.
- Colorectal Cancer: Can metastasize to various organs, including the ovaries.
- Lung Cancer: Known for its potential to spread to multiple sites, including the reproductive organs.
- Endometrial Cancer: May also lead to secondary ovarian involvement.

Symptoms

Patients with secondary malignant neoplasms of the ovary may present with various symptoms, which can include:
- Abdominal pain or discomfort
- Bloating or swelling in the abdomen
- Changes in bowel habits
- Unexplained weight loss
- Ascites (fluid accumulation in the abdominal cavity)

Diagnosis

Diagnosis typically involves a combination of:
- Imaging Studies: Such as ultrasound, CT scans, or MRI to visualize the ovaries and assess for masses.
- Biopsy: To confirm the presence of malignant cells and determine the origin of the cancer.
- Tumor Markers: Blood tests for markers like CA-125, which can be elevated in ovarian cancer and other malignancies.

Coding and Billing Considerations

Importance of Accurate Coding

Accurate coding is crucial for proper billing and reimbursement, as well as for tracking cancer incidence and treatment outcomes. The use of C79.60 indicates that the neoplasm is secondary and unspecified, which can affect treatment decisions and prognosis assessments.

  • C79.61: Secondary malignant neoplasm of right ovary
  • C79.62: Secondary malignant neoplasm of left ovary

These codes provide more specific information regarding the location of the metastatic disease, which can be important for treatment planning.

Conclusion

The ICD-10 code C79.60 is essential for identifying cases of secondary malignant neoplasms affecting the ovaries when the specific ovary involved is not specified. Understanding the implications of this diagnosis, including potential primary cancer sites and associated symptoms, is vital for healthcare providers in managing patient care effectively. Accurate coding not only aids in treatment but also contributes to broader cancer research and epidemiology efforts.

Clinical Information

The ICD-10 code C79.60 refers to a secondary malignant neoplasm of an unspecified ovary, indicating that cancer has metastasized to the ovary from another primary site. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for diagnosis and management.

Clinical Presentation

Overview

Secondary malignant neoplasms of the ovary often arise from cancers originating in other organs, such as the breast, colon, or stomach. The clinical presentation can vary significantly based on the primary cancer type, the extent of metastasis, and the individual patient's health status.

Signs and Symptoms

Patients with secondary malignant neoplasms of the ovary may present with a range of symptoms, which can include:

  • Abdominal Pain: Often a common complaint, abdominal pain may be due to the mass effect of the tumor or associated complications such as ascites.
  • Abdominal Distension: This can occur due to fluid accumulation (ascites) or the presence of a tumor.
  • Changes in Bowel Habits: Patients may experience constipation or diarrhea, depending on the tumor's location and size.
  • Weight Loss: Unintentional weight loss may occur due to cancer cachexia or decreased appetite.
  • Nausea and Vomiting: These symptoms can arise from gastrointestinal obstruction or other complications.
  • Menstrual Irregularities: Although less common, some patients may experience changes in their menstrual cycle due to hormonal influences or the presence of a tumor.
  • Fatigue: Generalized fatigue is a common symptom in cancer patients, often related to anemia or the metabolic demands of the tumor.

Physical Examination Findings

During a physical examination, healthcare providers may note:

  • Palpable Mass: A mass may be felt during a pelvic examination, indicating the presence of an ovarian tumor.
  • Ascites: Fluid accumulation in the abdominal cavity may be detected, often leading to abdominal distension.
  • Lymphadenopathy: Enlarged lymph nodes may be present, particularly if the cancer has spread to regional lymph nodes.

Patient Characteristics

Demographics

  • Age: Secondary ovarian neoplasms can occur in a wide age range, but they are more commonly diagnosed in older adults, particularly those over 50 years of age.
  • Gender: While the primary diagnosis is specific to females, the underlying cancers leading to metastasis can affect both genders.

Risk Factors

  • History of Cancer: Patients with a prior diagnosis of cancer, particularly breast, colorectal, or gastric cancer, are at increased risk for developing secondary ovarian neoplasms.
  • Genetic Predisposition: Certain genetic factors, such as BRCA mutations, may increase the risk of ovarian cancer and its metastasis.

Comorbidities

Patients may present with various comorbid conditions that can complicate the management of secondary ovarian neoplasms, including:

  • Cardiovascular Disease: Pre-existing heart conditions may affect treatment options.
  • Diabetes: This can influence overall health and treatment response.
  • Obesity: Higher body mass index (BMI) can complicate surgical interventions and affect prognosis.

Conclusion

The clinical presentation of secondary malignant neoplasms of the ovary (ICD-10 code C79.60) is characterized by a variety of symptoms, including abdominal pain, weight loss, and changes in bowel habits. Patient characteristics such as age, history of cancer, and comorbidities play a significant role in the diagnosis and management of this condition. Early recognition and appropriate management are essential for improving patient outcomes and quality of life.

Diagnostic Criteria

The diagnosis of secondary malignant neoplasm of the ovary, represented by the ICD-10 code C79.60, involves a comprehensive evaluation based on clinical, imaging, and pathological criteria. Here’s a detailed overview of the criteria typically used for this diagnosis.

Clinical Criteria

  1. Patient History:
    - A thorough medical history is essential, particularly focusing on any previous malignancies. Patients with a known history of cancer, especially those originating from other sites such as breast, colon, or endometrium, are at higher risk for secondary malignancies in the ovaries[1].

  2. Symptoms:
    - Common symptoms may include abdominal pain, bloating, changes in bowel habits, or unexplained weight loss. However, many patients may be asymptomatic, making history-taking crucial[1].

Imaging Studies

  1. Ultrasound:
    - Pelvic ultrasound is often the first imaging modality used. It can help identify ovarian masses, cysts, or other abnormalities. The presence of solid masses or complex cysts may raise suspicion for malignancy[1].

  2. CT or MRI Scans:
    - Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) can provide more detailed images of the ovaries and surrounding structures. These imaging techniques help assess the extent of disease and identify any metastatic lesions[1].

Pathological Criteria

  1. Tissue Biopsy:
    - A definitive diagnosis often requires a biopsy of the ovarian tissue. This can be performed via laparoscopy or during surgery. Histological examination is crucial to confirm the presence of malignant cells and to determine their origin[1].

  2. Immunohistochemistry:
    - In cases where the primary tumor is unknown, immunohistochemical staining can help identify the tissue of origin. This is particularly important for distinguishing between primary ovarian cancer and secondary neoplasms[1].

Laboratory Tests

  1. Tumor Markers:
    - Blood tests for tumor markers such as CA-125 may be utilized. Elevated levels of CA-125 can indicate ovarian cancer, but they are not specific to secondary malignancies. Therefore, they should be interpreted in conjunction with other diagnostic findings[1][2].

Conclusion

The diagnosis of secondary malignant neoplasm of the ovary (ICD-10 code C79.60) is multifaceted, relying on a combination of clinical history, imaging studies, pathological evaluation, and laboratory tests. Each component plays a critical role in establishing the diagnosis and guiding subsequent management. If there are any uncertainties or if the primary cancer site is unknown, further investigations may be warranted to ensure accurate diagnosis and treatment planning.

Treatment Guidelines

The ICD-10 code C79.60 refers to a secondary malignant neoplasm of an unspecified ovary, indicating that cancer has metastasized to the ovary from another primary site. Understanding the standard treatment approaches for this condition involves a multi-faceted strategy, as it typically requires addressing both the metastatic disease and the primary cancer.

Overview of Secondary Malignant Neoplasms

Secondary malignant neoplasms occur when cancer cells spread from their original site to other parts of the body. In the case of C79.60, the ovary is affected, which can complicate treatment due to the nature of metastatic disease. The treatment plan often depends on several factors, including the type of primary cancer, the extent of metastasis, the patient's overall health, and specific characteristics of the tumor.

Standard Treatment Approaches

1. Systemic Therapy

Systemic therapy is often the cornerstone of treatment for secondary malignancies. This may include:

  • Chemotherapy: Depending on the primary cancer type, chemotherapy regimens may be employed. For example, if the primary cancer is breast cancer, agents like anthracyclines or taxanes may be used. In cases of colorectal cancer, oxaliplatin or irinotecan might be included in the regimen[1].

  • Targeted Therapy: If the primary cancer has specific genetic mutations, targeted therapies may be appropriate. For instance, trastuzumab is used for HER2-positive breast cancer, which can also metastasize to the ovaries[2].

  • Hormonal Therapy: In cases where the primary cancer is hormone-sensitive (like some breast or prostate cancers), hormonal therapies may be utilized to slow the growth of metastatic lesions[3].

2. Surgical Intervention

Surgical options may be considered based on the extent of the disease:

  • Debulking Surgery: If the metastatic tumors in the ovaries are causing significant symptoms or if there is a possibility of complete resection, debulking surgery may be performed. This involves removing as much of the tumor as possible[4].

  • Oophorectomy: In some cases, the surgical removal of one or both ovaries may be indicated, especially if the metastasis is localized and can be completely excised[5].

3. Radiation Therapy

Radiation therapy may be used in specific scenarios, particularly if the metastatic lesions are causing pain or other symptoms. It can also be part of palliative care to improve the quality of life for patients with advanced disease[6].

4. Palliative Care

For patients with advanced metastatic disease, palliative care becomes crucial. This approach focuses on relieving symptoms and improving the quality of life rather than attempting to cure the disease. Palliative care may include pain management, nutritional support, and psychological counseling[7].

Multidisciplinary Approach

A multidisciplinary team, including oncologists, surgeons, radiologists, and palliative care specialists, is essential for developing a comprehensive treatment plan tailored to the individual patient's needs. Regular follow-ups and imaging studies are also important to monitor the disease's progression and treatment response.

Conclusion

The treatment of secondary malignant neoplasms of the ovary, as indicated by ICD-10 code C79.60, is complex and requires a personalized approach based on the primary cancer type and the patient's overall condition. Systemic therapies, surgical options, and palliative care play critical roles in managing this condition. Ongoing research and clinical trials continue to evolve treatment strategies, offering hope for improved outcomes in patients facing metastatic disease.


References

  1. National Clinical Coding Standards ICD-10 5th Edition.
  2. Trastuzumab Biologics (A56660) - Billing and Coding.
  3. CG-LAB-32 Cancer Antigen 125 Testing.
  4. How to Report Ovarian Cancer Using ICD-10 and CPT.
  5. CG-LAB-33 Carcinoembryonic Antigen Testing.
  6. Trastuzumab - MCS.
  7. The South African ICD-10 Morbidity Coding Standards and Guidelines.

Related Information

Approximate Synonyms

  • Metastatic Ovarian Cancer
  • Secondary Ovarian Tumor
  • Ovarian Metastasis

Description

  • Secondary malignant neoplasm of ovary
  • Cancer spreads from primary site
  • Metastasized to ovaries
  • Part of female reproductive system
  • Advanced disease and poorer prognosis
  • Common primary sites: breast, colon, lung, endometrium
  • Symptoms: abdominal pain, bloating, weight loss, ascites

Clinical Information

  • Abdominal pain often a common complaint
  • Abdominal distension due to fluid accumulation or tumor
  • Changes in bowel habits due to tumor location and size
  • Weight loss due to cancer cachexia or decreased appetite
  • Nausea and vomiting from gastrointestinal obstruction
  • Menstrual irregularities due to hormonal influences or tumor
  • Generalized fatigue common in cancer patients
  • Palpable mass felt during pelvic examination
  • Ascites detected by fluid accumulation in abdominal cavity
  • Lymphadenopathy present with enlarged lymph nodes
  • Risk of secondary ovarian neoplasms increased with prior cancer diagnosis
  • Genetic predisposition such as BRCA mutations may increase risk
  • Comorbid conditions like cardiovascular disease and diabetes complicate management

Diagnostic Criteria

  • Patient history of previous malignancies
  • Abdominal pain or unexplained weight loss symptoms
  • Solid ovarian masses on ultrasound imaging
  • Complex cysts or metastatic lesions on CT/MRI scans
  • Malignant cells confirmed via tissue biopsy
  • Immunohistochemistry for identifying tissue of origin
  • Elevated tumor markers (CA-125) in blood tests

Treatment Guidelines

  • Systemic therapy is cornerstone treatment
  • Chemotherapy may be used depending on primary cancer type
  • Targeted therapy for specific genetic mutations
  • Hormonal therapy for hormone-sensitive cancers
  • Debulking surgery to remove as much tumor as possible
  • Oophorectomy may be indicated for localized metastasis
  • Radiation therapy for symptom control or palliative care
  • Palliative care focuses on relieving symptoms and improving quality of life

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