ICD-10: D35.6

Benign neoplasm of aortic body and other paraganglia

Clinical Information

Inclusion Terms

  • Benign tumor of glomus jugulare

Additional Information

Description

The ICD-10 code D35.6 refers to a benign neoplasm of the aortic body and other paraganglia. This classification is part of the broader category of benign neoplasms, which are non-cancerous tumors that can occur in various tissues and organs throughout the body. Below is a detailed clinical description and relevant information regarding this specific code.

Clinical Description

Definition

A benign neoplasm is a growth that does not invade surrounding tissues or metastasize to other parts of the body. The aortic body, also known as the carotid body, is a small cluster of chemoreceptor cells located near the aorta and carotid arteries. Paraganglia are neuroendocrine tissues that can be found throughout the body, often associated with the autonomic nervous system.

Characteristics

  • Location: The aortic body and paraganglia are primarily located near major blood vessels, including the aorta and carotid arteries. They play a role in regulating blood pressure and oxygen levels in the blood.
  • Symptoms: Many benign neoplasms in this area may be asymptomatic. However, if they grow large enough, they can cause symptoms such as:
  • Palpitations
  • Hypertension (high blood pressure)
  • Headaches
  • Dizziness
  • Localized pain or discomfort

Diagnosis

Diagnosis typically involves imaging studies such as:
- Ultrasound: To visualize the mass and assess its characteristics.
- CT or MRI scans: To provide detailed images of the neoplasm and surrounding structures.
- Biopsy: In some cases, a tissue sample may be taken to confirm the benign nature of the tumor.

Treatment

Treatment for benign neoplasms of the aortic body and paraganglia may vary based on the size and symptoms:
- Observation: If the neoplasm is small and asymptomatic, a watchful waiting approach may be adopted.
- Surgical Removal: If the neoplasm is causing symptoms or is large, surgical excision may be necessary.

The D35.6 code falls under the broader category of D35 which includes benign neoplasms of other and unspecified endocrine glands. This classification is important for accurate billing and coding in medical records and insurance claims.

Importance in Clinical Practice

Understanding the specifics of ICD-10 code D35.6 is crucial for healthcare providers in diagnosing and managing patients with benign neoplasms in this region. Accurate coding ensures proper treatment pathways and facilitates communication among healthcare professionals.

Conclusion

In summary, the ICD-10 code D35.6 identifies benign neoplasms of the aortic body and other paraganglia, which are generally non-cancerous growths that may require monitoring or surgical intervention depending on their size and associated symptoms. Awareness of this condition is essential for effective diagnosis and management in clinical settings.

Clinical Information

The ICD-10 code D35.6 refers to a benign neoplasm of the aortic body and other paraganglia. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is essential for accurate diagnosis and management.

Clinical Presentation

Benign neoplasms of the aortic body and paraganglia are typically slow-growing tumors that may not present with significant symptoms initially. These tumors arise from the paraganglionic tissue, which is involved in the autonomic nervous system and is found in various locations throughout the body, including near the aorta.

Signs and Symptoms

  1. Asymptomatic Nature: Many patients with benign neoplasms of the aortic body may be asymptomatic, especially in the early stages. These tumors are often discovered incidentally during imaging studies for unrelated conditions[1].

  2. Symptoms Related to Tumor Size: As the tumor grows, it may exert pressure on surrounding structures, leading to various symptoms:
    - Chest Pain: Due to pressure on the thoracic structures.
    - Dyspnea: Difficulty breathing if the tumor compresses the airways or lungs.
    - Dysphagia: Difficulty swallowing if the esophagus is compressed.
    - Palpitations: If the tumor secretes catecholamines, it may lead to symptoms of increased heart rate and blood pressure[1][2].

  3. Paroxysmal Symptoms: In some cases, particularly with functional paragangliomas, patients may experience episodes of hypertension, headaches, sweating, and palpitations due to catecholamine release, mimicking pheochromocytoma symptoms[2].

Patient Characteristics

  1. Demographics:
    - Age: These tumors can occur in adults of any age but are more commonly diagnosed in middle-aged individuals.
    - Gender: There is no significant gender predilection noted in the literature, although some studies suggest a slight male predominance[2].

  2. Family History: A family history of paragangliomas or related syndromes (such as Multiple Endocrine Neoplasia) may be present, indicating a genetic predisposition in some cases[1].

  3. Comorbid Conditions: Patients may have other comorbidities, particularly cardiovascular conditions, which can complicate the clinical picture. The presence of hypertension or other endocrine disorders may also be relevant, especially if the tumor is functional[2].

  4. Genetic Factors: Certain genetic mutations, such as those in the SDH (succinate dehydrogenase) genes, are associated with familial paraganglioma syndromes, which can influence the clinical presentation and management of these tumors[1].

Conclusion

In summary, benign neoplasms of the aortic body and other paraganglia (ICD-10 code D35.6) often present asymptomatically but can lead to significant clinical symptoms as they grow. Understanding the signs, symptoms, and patient characteristics is crucial for healthcare providers to ensure timely diagnosis and appropriate management. Regular monitoring and imaging may be necessary for asymptomatic patients, while symptomatic individuals may require surgical intervention or other therapeutic approaches depending on the tumor's behavior and associated symptoms.

Approximate Synonyms

The ICD-10 code D35.6 refers to a benign neoplasm of the aortic body and other paraganglia. This classification encompasses various alternative names and related terms that can help in understanding the condition better. Below are some of the key terms associated with this diagnosis.

Alternative Names

  1. Aortic Body Tumor: This term specifically refers to tumors arising from the aortic body, which is a small cluster of chemoreceptor cells located near the aorta.

  2. Paraganglioma: This is a broader term that includes tumors originating from paraganglia, which are neuroendocrine tissues found throughout the body, including near the aorta.

  3. Carotid Body Tumor: While this specifically refers to tumors of the carotid body, it is often discussed in conjunction with aortic body tumors due to their similar origins and functions.

  4. Neuroendocrine Tumor: This term encompasses a variety of tumors that arise from neuroendocrine cells, including those found in paraganglia.

  5. Benign Paraganglioma: This term emphasizes the benign nature of the tumor, distinguishing it from malignant forms.

  1. Endocrine Neoplasm: This term refers to tumors that arise from endocrine tissues, which can include paraganglia.

  2. Neoplasm of Other and Unspecified Endocrine Glands: This broader category includes various benign neoplasms that do not fit into more specific classifications.

  3. Tumor of the Aortic Body: A more general term that can be used interchangeably with aortic body tumor.

  4. Chemoreceptor Tumor: Since the aortic body functions as a chemoreceptor, this term can also be relevant.

  5. Vascular Tumor: This term may be used in a broader context to describe tumors associated with blood vessels, including those near the aorta.

Understanding these alternative names and related terms can be beneficial for healthcare professionals when discussing diagnoses, treatment options, and coding for medical billing purposes. Each term may have specific implications in clinical practice, so familiarity with them is essential for accurate communication and documentation.

Diagnostic Criteria

The diagnosis of a benign neoplasm of the aortic body and other paraganglia, classified under ICD-10 code D35.6, involves several criteria and considerations. Understanding these criteria is essential for accurate diagnosis and coding in clinical practice.

Clinical Presentation

Symptoms

Patients with benign neoplasms of the aortic body and paraganglia may present with various symptoms, although many cases can be asymptomatic. Common symptoms may include:

  • Palpitations: Due to catecholamine secretion, which can lead to increased heart rate.
  • Hypertension: Persistent high blood pressure may occur as a result of hormone release.
  • Headaches: Often related to episodes of hypertension.
  • Sweating: Excessive sweating can be a symptom of catecholamine-secreting tumors.

Physical Examination

During a physical examination, healthcare providers may look for signs of hypertension or other systemic effects related to hormone secretion.

Diagnostic Imaging

Imaging Techniques

To confirm the presence of a benign neoplasm in the aortic body or paraganglia, several imaging modalities may be utilized:

  • Ultrasound: Can help visualize the mass and assess its characteristics.
  • CT Scan (Computed Tomography): Provides detailed images of the aortic body and surrounding structures, helping to identify the size and extent of the neoplasm.
  • MRI (Magnetic Resonance Imaging): Useful for characterizing the tumor and differentiating it from other masses.
  • Nuclear Medicine Scans: Such as MIBG (metaiodobenzylguanidine) scans, can be particularly helpful in identifying neuroendocrine tumors.

Histopathological Examination

Biopsy

A definitive diagnosis often requires a biopsy of the tumor. Histopathological examination can confirm the benign nature of the neoplasm. Key features that pathologists look for include:

  • Cellular Characteristics: The presence of well-differentiated cells without atypical features.
  • Lack of Invasion: Benign tumors do not invade surrounding tissues.
  • Absence of Metastasis: Benign neoplasms do not spread to other parts of the body.

Laboratory Tests

Hormonal Assays

In cases where a functional tumor is suspected, laboratory tests may be performed to measure levels of catecholamines and their metabolites in the blood or urine. Elevated levels can indicate a functioning paraganglioma.

Conclusion

The diagnosis of a benign neoplasm of the aortic body and other paraganglia (ICD-10 code D35.6) is based on a combination of clinical presentation, imaging studies, histopathological examination, and laboratory tests. Accurate diagnosis is crucial for appropriate management and treatment planning. If you have further questions or need more specific information, feel free to ask!

Treatment Guidelines

When addressing the standard treatment approaches for ICD-10 code D35.6, which refers to benign neoplasms of the aortic body and other paraganglia, it is essential to understand the nature of these tumors and the typical management strategies employed.

Understanding Benign Neoplasms of Paraganglia

Paraganglia are clusters of neuroendocrine cells that can be found throughout the body, including near the aorta. Benign neoplasms in this category, such as glomus tumors, are generally slow-growing and may not present significant symptoms unless they exert pressure on surrounding structures. The management of these tumors often depends on their size, location, and the symptoms they may cause.

Standard Treatment Approaches

1. Observation and Monitoring

For small, asymptomatic benign neoplasms, a conservative approach may be adopted. This involves regular monitoring through imaging studies, such as ultrasound or MRI, to assess any changes in size or symptoms over time. This strategy is particularly relevant for patients who are elderly or have comorbid conditions that may complicate surgical interventions[1].

2. Surgical Intervention

Surgery is the primary treatment for symptomatic benign neoplasms or those that are growing. The goals of surgical intervention include:

  • Complete Resection: The primary aim is to remove the tumor entirely, which can alleviate symptoms and prevent complications. Surgical techniques may vary based on the tumor's location and size, and may involve open surgery or minimally invasive approaches[2].
  • Preservation of Surrounding Structures: Care is taken to preserve nearby nerves and blood vessels during surgery to minimize complications and maintain function[3].

3. Endovascular Techniques

In some cases, particularly for tumors located in challenging anatomical positions, endovascular techniques may be considered. These minimally invasive procedures can involve embolization, where blood supply to the tumor is reduced, potentially leading to tumor shrinkage or alleviation of symptoms[4].

4. Follow-Up Care

Post-treatment follow-up is crucial to monitor for recurrence or complications. This typically involves regular imaging and clinical evaluations to ensure that the patient remains asymptomatic and that any potential recurrence is detected early[5].

Conclusion

The management of benign neoplasms of the aortic body and other paraganglia primarily revolves around observation for asymptomatic cases and surgical intervention for symptomatic or growing tumors. The choice of treatment should be individualized based on the patient's overall health, the tumor's characteristics, and the potential risks associated with surgery. Regular follow-up is essential to ensure ongoing health and to address any future concerns promptly.

For further information or specific case management, consulting with a specialist in oncology or surgery may provide additional insights tailored to individual patient needs.

Related Information

Description

Clinical Information

  • Typically slow-growing tumors
  • Often asymptomatic initially
  • May cause chest pain and dyspnea
  • Can lead to palpitations and hypertension
  • May be discovered incidentally during imaging
  • May have family history of paragangliomas or related syndromes
  • Genetic factors influence clinical presentation

Approximate Synonyms

  • Aortic Body Tumor
  • Paraganglioma
  • Carotid Body Tumor
  • Neuroendocrine Tumor
  • Benign Paraganglioma
  • Endocrine Neoplasm
  • Neoplasm of Other and Unspecified Endocrine Glands
  • Tumor of the Aortic Body
  • Chemoreceptor Tumor
  • Vascular Tumor

Diagnostic Criteria

  • Clinical symptoms include palpitations
  • Hypertension may occur due to hormone release
  • Headaches often related to hypertension episodes
  • Excessive sweating can be a symptom
  • Ultrasound helps visualize the mass and assess its characteristics
  • CT Scan provides detailed images of the tumor size and extent
  • MRI characterizes the tumor and differentiates it from other masses
  • Nuclear Medicine Scans help identify neuroendocrine tumors
  • Histopathological examination confirms benign nature
  • Lack of invasion is a key feature in histopathology
  • Absence of metastasis confirms benign neoplasm
  • Elevated catecholamine levels indicate functional tumor

Treatment Guidelines

  • Monitor small asymptomatic tumors
  • Surgery for symptomatic growing tumors
  • Complete resection of tumor tissue
  • Preserve surrounding nerves and blood vessels
  • Endovascular techniques for difficult locations
  • Embolization to reduce tumor supply
  • Regular post-treatment follow-up care

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.