ICD-10: E09.355

Drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy

Additional Information

Approximate Synonyms

ICD-10 code E09.355 refers to "Drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy." This specific code is part of a broader classification system used to categorize various health conditions, particularly those related to diabetes and its complications. Below are alternative names and related terms associated with this code.

Alternative Names

  1. Drug-Induced Diabetes Mellitus: This term emphasizes that the diabetes is a result of medication or chemical exposure.
  2. Chemical-Induced Diabetes: Similar to the above, this term highlights the role of chemicals in the onset of diabetes.
  3. Proliferative Diabetic Retinopathy: This term refers specifically to the eye condition that can develop as a complication of diabetes, indicating the presence of new blood vessel growth in the retina.
  1. Diabetes Mellitus: A general term for a group of diseases that affect how the body uses blood sugar (glucose).
  2. Stable Proliferative Diabetic Retinopathy: This indicates that the proliferative diabetic retinopathy is not currently worsening, which is a critical aspect of the condition.
  3. Secondary Diabetes: This term can be used to describe diabetes that is a consequence of another condition or external factors, such as medications.
  4. Retinopathy: A broader term that refers to damage to the retina, which can occur in various forms, including diabetic retinopathy.
  5. Endocrine Disorders: This term encompasses a range of conditions affecting hormone-producing glands, including those that can lead to diabetes.

Clinical Context

Understanding these terms is essential for healthcare professionals when diagnosing and coding for diabetes-related conditions. The classification of diabetes, particularly when induced by drugs or chemicals, is crucial for treatment planning and management of complications such as diabetic retinopathy.

In clinical practice, accurate coding using ICD-10 is vital for billing, insurance claims, and epidemiological studies, ensuring that patients receive appropriate care based on their specific conditions.

In summary, E09.355 is a specific code that highlights the intersection of drug-induced diabetes and its complications, particularly in relation to eye health. Familiarity with alternative names and related terms can enhance communication among healthcare providers and improve patient outcomes.

Clinical Information

The ICD-10 code E09.355 refers to "Drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy." This condition arises when diabetes is triggered by certain medications or chemicals, leading to complications such as diabetic retinopathy. Below, we will explore the clinical presentation, signs, symptoms, and patient characteristics associated with this diagnosis.

Clinical Presentation

Overview of Drug or Chemical Induced Diabetes Mellitus

Drug or chemical induced diabetes mellitus occurs when specific medications or substances disrupt normal glucose metabolism, resulting in hyperglycemia. Common culprits include corticosteroids, certain antipsychotics, and other medications that can affect insulin sensitivity or secretion. The onset of diabetes in these cases can be rapid, often occurring within weeks to months of exposure to the offending agent.

Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is a severe form of diabetic eye disease characterized by the growth of new blood vessels in the retina, which can lead to vision loss. In patients with E09.355, the retinopathy is described as "stable," indicating that while the condition is present, it has not progressed or worsened significantly.

Signs and Symptoms

Common Symptoms of Diabetes Mellitus

Patients with drug or chemical induced diabetes may present with classic symptoms of diabetes, including:
- Polyuria: Increased urination due to elevated blood glucose levels.
- Polydipsia: Excessive thirst as the body attempts to compensate for fluid loss.
- Polyphagia: Increased hunger, often due to the body's inability to utilize glucose effectively.
- Fatigue: Generalized tiredness resulting from poor glucose utilization.
- Blurred Vision: Changes in fluid levels can affect the lens of the eye, leading to temporary vision changes.

Symptoms of Proliferative Diabetic Retinopathy

Patients with stable proliferative diabetic retinopathy may not exhibit symptoms until the condition progresses. However, some signs may include:
- Floaters: Small spots or lines that appear in the field of vision.
- Flashes of Light: Sudden bursts of light in the peripheral vision.
- Dark Areas in Vision: Areas of vision that may appear shadowy or obscured.
- Vision Loss: In advanced cases, patients may experience significant vision impairment.

Patient Characteristics

Demographics

  • Age: Patients can vary widely in age, but drug-induced diabetes is often seen in adults, particularly those on long-term medication regimens.
  • Gender: Both males and females can be affected, though certain medications may have gender-specific risks.

Medical History

  • Medication Use: A detailed history of medications is crucial, as the onset of diabetes may correlate with the initiation of specific drugs.
  • Comorbid Conditions: Patients may have other health issues, such as hypertension or hyperlipidemia, which are common in individuals with diabetes.

Risk Factors

  • Obesity: Patients with a higher body mass index (BMI) may be more susceptible to drug-induced diabetes.
  • Family History: A family history of diabetes can increase the risk of developing diabetes when exposed to certain medications.
  • Lifestyle Factors: Sedentary lifestyle and poor dietary habits can exacerbate the effects of drug-induced diabetes.

Conclusion

Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with ICD-10 code E09.355 is essential for effective diagnosis and management. Clinicians should be vigilant in monitoring patients who are on medications known to induce diabetes, particularly for signs of diabetic retinopathy. Regular eye examinations and glucose monitoring are critical components of care for these patients to prevent complications and maintain quality of life.

Diagnostic Criteria

The diagnosis of ICD-10 code E09.355, which refers to drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy, involves a combination of clinical criteria and diagnostic tests. Below is a detailed overview of the criteria used for this diagnosis.

Understanding Drug or Chemical Induced Diabetes Mellitus

Drug or chemical induced diabetes mellitus occurs when certain medications or chemicals lead to the development of diabetes. This can happen through various mechanisms, including insulin resistance or direct damage to pancreatic beta cells. Common culprits include glucocorticoids, antipsychotics, and certain chemotherapy agents[1].

Diagnostic Criteria for Diabetes Mellitus

To diagnose diabetes mellitus, including drug or chemical induced types, healthcare providers typically use the following criteria established by the American Diabetes Association (ADA):

  1. Fasting Plasma Glucose (FPG):
    - A fasting plasma glucose level of 126 mg/dL (7.0 mmol/L) or higher. Fasting is defined as no caloric intake for at least 8 hours.

  2. Oral Glucose Tolerance Test (OGTT):
    - A 2-hour plasma glucose level of 200 mg/dL (11.1 mmol/L) or higher during an OGTT, which involves administering a glucose solution.

  3. A1C Test:
    - A hemoglobin A1C level of 6.5% (48 mmol/mol) or higher. This test reflects average blood glucose levels over the past 2 to 3 months.

  4. Random Plasma Glucose:
    - A random plasma glucose level of 200 mg/dL (11.1 mmol/L) or higher in a patient with classic symptoms of hyperglycemia or hyperglycemic crisis[2].

Specific Considerations for E09.355

For the specific diagnosis of E09.355, the following additional criteria must be met:

  • Identification of Drug or Chemical Exposure:
  • A clear history of exposure to a drug or chemical known to induce diabetes must be documented. This includes a review of the patient's medication history and any relevant laboratory tests that indicate the presence of the drug or its metabolites.

  • Assessment of Diabetic Retinopathy:

  • The presence of proliferative diabetic retinopathy must be confirmed through a comprehensive eye examination. This may include:

    • Fundoscopy or retinal imaging to identify neovascularization or other changes associated with proliferative diabetic retinopathy.
    • Classification of the retinopathy as stable, which indicates that there has been no progression of the disease over a specified period.
  • Monitoring and Management:

  • Regular monitoring of blood glucose levels and retinal health is essential to ensure that the diabetes remains stable and that the retinopathy does not progress. This may involve follow-up visits with both endocrinology and ophthalmology specialists[3].

Conclusion

The diagnosis of ICD-10 code E09.355 requires a comprehensive approach that includes confirming diabetes through established glucose criteria, identifying the specific drug or chemical responsible for the condition, and assessing the presence and stability of proliferative diabetic retinopathy. Proper documentation and ongoing management are crucial for effective treatment and monitoring of patients with this diagnosis. If you have further questions or need additional information, feel free to ask!

Treatment Guidelines

When addressing the standard treatment approaches for ICD-10 code E09.355, which refers to drug or chemical-induced diabetes mellitus with stable proliferative diabetic retinopathy, it is essential to consider both the management of diabetes and the specific treatment of diabetic retinopathy. Below is a detailed overview of the treatment strategies involved.

Understanding E09.355: Drug or Chemical Induced Diabetes Mellitus

ICD-10 code E09.355 indicates diabetes mellitus that has been induced by drugs or chemicals, alongside the presence of stable proliferative diabetic retinopathy (PDR). This condition arises when certain medications, such as corticosteroids or antipsychotics, lead to elevated blood glucose levels, resulting in diabetes. Proliferative diabetic retinopathy is a severe form of diabetic eye disease characterized by the growth of new blood vessels in the retina, which can lead to vision loss if not managed properly.

Treatment Approaches

1. Management of Diabetes Mellitus

A. Glycemic Control
- Medications: The primary goal is to achieve optimal glycemic control. This may involve the use of oral hypoglycemic agents or insulin therapy, depending on the severity of the diabetes and the patient's overall health. Common medications include metformin, sulfonylureas, and insulin analogs.
- Monitoring: Regular monitoring of blood glucose levels is crucial. Patients should aim for an HbA1c level below 7% to minimize complications associated with diabetes[1].

B. Lifestyle Modifications
- Diet: A balanced diet low in simple sugars and high in fiber can help manage blood glucose levels. Patients are often advised to consult with a dietitian for personalized meal planning.
- Exercise: Regular physical activity is recommended to improve insulin sensitivity and overall health. Patients should engage in at least 150 minutes of moderate-intensity aerobic exercise per week[1].

2. Treatment of Proliferative Diabetic Retinopathy

A. Monitoring and Assessment
- Regular Eye Exams: Patients with PDR should undergo regular eye examinations by an ophthalmologist to monitor the progression of the disease and assess the need for intervention[2].

B. Laser Therapy
- Panretinal Photocoagulation (PRP): This is the standard treatment for PDR. It involves using laser treatment to create small burns in the peripheral retina, which helps reduce the risk of vision loss by decreasing the drive for new blood vessel growth[2].

C. Anti-VEGF Therapy
- Injections: Anti-vascular endothelial growth factor (anti-VEGF) medications, such as ranibizumab or aflibercept, may be used to treat complications of PDR, particularly if there is associated macular edema. These injections help to reduce fluid leakage and inhibit abnormal blood vessel growth[2].

D. Vitrectomy
- Surgical Intervention: In cases where there is significant bleeding into the vitreous or retinal detachment, a vitrectomy may be necessary. This surgical procedure involves removing the vitreous gel and any scar tissue that may be pulling on the retina[2].

3. Addressing Underlying Causes

A. Review of Medications
- Identifying Causative Agents: It is crucial to review the patient's medication list to identify any drugs that may have contributed to the development of diabetes. If possible, alternative medications should be considered to manage the underlying condition without exacerbating blood glucose levels[1].

B. Multidisciplinary Approach
- Collaboration: A multidisciplinary approach involving endocrinologists, ophthalmologists, and primary care providers is essential for comprehensive management. This ensures that both diabetes and its complications are addressed effectively[1][2].

Conclusion

The management of E09.355 requires a comprehensive approach that focuses on controlling blood glucose levels and treating the complications associated with proliferative diabetic retinopathy. By implementing a combination of pharmacological treatments, lifestyle modifications, and regular monitoring, healthcare providers can help patients maintain their health and prevent further complications. Regular follow-ups and a collaborative care model are vital to ensure optimal outcomes for patients with drug or chemical-induced diabetes and associated eye conditions.

Description

ICD-10 code E09.355 refers to "Drug or chemical induced diabetes mellitus with stable proliferative diabetic retinopathy." This classification is part of the broader category of drug or chemical-induced diabetes mellitus, which is a condition where diabetes develops as a direct result of exposure to certain medications or chemicals.

Clinical Description

Drug or Chemical Induced Diabetes Mellitus

Drug or chemical induced diabetes mellitus (E09) occurs when specific substances lead to the onset of diabetes. This can happen through various mechanisms, including insulin resistance or direct damage to pancreatic beta cells, which are responsible for insulin production. Common culprits include:

  • Glucocorticoids: Often used in the treatment of inflammatory conditions, these can increase blood glucose levels.
  • Antipsychotics: Certain medications, particularly atypical antipsychotics, have been associated with weight gain and insulin resistance.
  • Chemotherapy agents: Some cancer treatments can affect glucose metabolism.

Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is a severe form of diabetic eye disease characterized by the growth of new blood vessels in the retina, which can lead to vision loss. The term "stable" indicates that the condition is not currently worsening, but it requires ongoing monitoring and management. Key features of PDR include:

  • Neovascularization: The formation of new, fragile blood vessels that can bleed into the vitreous humor.
  • Fibrous tissue formation: This can lead to retinal detachment if not managed properly.
  • Vision changes: Patients may experience blurred vision, floaters, or sudden vision loss.

Clinical Management

Management of patients with E09.355 involves a multidisciplinary approach, including:

  • Monitoring and controlling blood glucose levels: This is crucial to prevent further complications.
  • Regular eye examinations: Patients should undergo dilated eye exams to monitor for changes in retinopathy.
  • Treatment options for retinopathy: Depending on the severity, treatments may include laser therapy, anti-VEGF injections, or vitrectomy.

Risk Factors

Patients with drug or chemical induced diabetes mellitus are often at higher risk for developing complications such as diabetic retinopathy due to the underlying metabolic disturbances caused by the medications. Factors that may exacerbate the condition include:

  • Duration of diabetes: Longer duration increases the risk of complications.
  • Poor glycemic control: Elevated blood glucose levels can accelerate the progression of retinopathy.
  • Hypertension and dyslipidemia: These conditions can further increase the risk of vascular complications.

Conclusion

ICD-10 code E09.355 encapsulates a specific clinical scenario where diabetes mellitus is induced by drugs or chemicals, accompanied by stable proliferative diabetic retinopathy. Effective management requires careful monitoring of blood glucose levels, regular ophthalmologic assessments, and appropriate interventions to mitigate the risk of vision loss. Understanding the interplay between medication use and diabetes complications is essential for optimizing patient outcomes.

Related Information

Approximate Synonyms

  • Drug-Induced Diabetes Mellitus
  • Chemical-Induced Diabetes
  • Proliferative Diabetic Retinopathy
  • Diabetes Mellitus
  • Stable Proliferative Diabetic Retinopathy
  • Secondary Diabetes
  • Retinopathy

Clinical Information

  • Diabetes triggered by certain medications or chemicals
  • Hyperglycemia occurs rapidly within weeks to months
  • Common culprits include corticosteroids and antipsychotics
  • Proliferative diabetic retinopathy is a severe form of eye disease
  • Stable proliferative diabetic retinopathy means the condition has not worsened
  • Symptoms include polyuria, polydipsia, polyphagia, fatigue, blurred vision
  • Floaters, flashes of light, dark areas in vision, and vision loss are possible
  • Age and gender can vary widely with this condition
  • Medication use is crucial to diagnose drug-induced diabetes
  • Comorbid conditions like hypertension and hyperlipidemia are common
  • Obesity, family history, and lifestyle factors increase the risk

Diagnostic Criteria

  • Fasting plasma glucose level ≥126 mg/dL
  • 2-hour plasma glucose level ≥200 mg/dL during OGTT
  • A1C level ≥6.5%
  • Random plasma glucose ≥200 mg/dL with symptoms of hyperglycemia
  • Clear history of drug or chemical exposure
  • Proliferative diabetic retinopathy confirmed through eye examination

Treatment Guidelines

  • Glycemic control with medications
  • Monitoring blood glucose levels
  • Balanced diet low in simple sugars
  • Regular exercise for improved insulin sensitivity
  • Panretinal photocoagulation (PRP) laser therapy
  • Anti-VEGF injections for macular edema
  • Vitrectomy surgery for retinal detachment

Description

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.