ICD-10: E11.359

Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema

Additional Information

Clinical Information

Type 2 diabetes mellitus (T2DM) is a chronic condition characterized by insulin resistance and relative insulin deficiency, leading to elevated blood glucose levels. One of the serious complications of diabetes is diabetic retinopathy, which can progress to proliferative diabetic retinopathy (PDR). The ICD-10 code E11.359 specifically refers to T2DM with proliferative diabetic retinopathy without macular edema. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for effective management and treatment.

Clinical Presentation

Overview of Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy is a severe form of diabetic retinopathy that occurs when new, abnormal blood vessels grow on the retina, a process known as neovascularization. This condition typically arises in patients with long-standing diabetes and is often asymptomatic in its early stages. However, as the disease progresses, it can lead to significant vision impairment or blindness if not treated promptly.

Signs and Symptoms

Patients with E11.359 may present with a variety of signs and symptoms, including:

  • Visual Disturbances: Patients may experience blurred vision, floaters, or sudden vision loss. These symptoms can vary in severity and may not be immediately recognized as related to diabetic retinopathy.
  • Retinal Hemorrhages: Upon examination, ophthalmologists may observe retinal hemorrhages, which are indicative of the abnormal blood vessel growth associated with PDR.
  • Exudates: Cotton wool spots and hard exudates may be present, although the absence of macular edema distinguishes this condition from other forms of diabetic retinopathy.
  • Neovascularization: The presence of new blood vessels on the retina or optic disc is a hallmark of proliferative diabetic retinopathy.

Patient Characteristics

Certain characteristics are commonly associated with patients diagnosed with E11.359:

  • Duration of Diabetes: Patients typically have a long history of diabetes, often more than 10 years, which increases the risk of developing diabetic retinopathy.
  • Poor Glycemic Control: Elevated HbA1c levels indicate chronic hyperglycemia, which is a significant risk factor for the development and progression of diabetic retinopathy.
  • Age: Most patients are middle-aged or older, as the risk of diabetic complications increases with age.
  • Comorbidities: Many patients may have additional health issues, such as hypertension or hyperlipidemia, which can exacerbate the risk of diabetic retinopathy.
  • Ethnicity: Certain ethnic groups, including African Americans, Hispanics, and Native Americans, are at a higher risk for developing diabetes and its complications, including PDR.

Conclusion

Proliferative diabetic retinopathy without macular edema, as classified under ICD-10 code E11.359, represents a critical stage in the progression of diabetic eye disease. Early detection and management are essential to prevent vision loss. Regular eye examinations, strict glycemic control, and management of comorbid conditions are vital components of care for patients with T2DM to mitigate the risk of developing PDR. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition can aid healthcare providers in delivering timely and effective interventions.

Approximate Synonyms

When discussing the ICD-10 code E11.359, which refers to Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema, it is essential to understand the alternative names and related terms that are commonly used in medical documentation and coding. Here’s a detailed overview:

Alternative Names

  1. Type 2 Diabetes with Proliferative Diabetic Retinopathy: This is a straightforward alternative name that emphasizes the condition of diabetic retinopathy associated with Type 2 diabetes.

  2. Proliferative Diabetic Retinopathy (PDR): While this term generally refers to the advanced stage of diabetic retinopathy, it is often used in conjunction with Type 2 diabetes to specify the underlying cause.

  3. Diabetic Retinopathy without Macular Edema: This term highlights the absence of macular edema, which is a critical distinction in the classification of diabetic retinopathy.

  4. Diabetes-Related Eye Disease: This broader term encompasses various eye conditions related to diabetes, including proliferative diabetic retinopathy.

  1. ICD-10-CM: The International Classification of Diseases, 10th Revision, Clinical Modification, which includes codes for various diseases and conditions, including diabetes and its complications.

  2. E11.35: This is a related code that refers to Type 2 diabetes mellitus with nonproliferative diabetic retinopathy, indicating a different stage of the disease.

  3. Diabetic Eye Disease: A general term that refers to all eye conditions caused by diabetes, including both nonproliferative and proliferative diabetic retinopathy.

  4. Retinal Neovascularization: This term describes the formation of new blood vessels in the retina, a hallmark of proliferative diabetic retinopathy.

  5. Vision Loss due to Diabetes: This phrase is often used in clinical settings to describe the potential outcome of untreated proliferative diabetic retinopathy.

  6. Ophthalmic Complications of Diabetes: This term encompasses all eye-related complications arising from diabetes, including diabetic retinopathy.

Conclusion

Understanding the alternative names and related terms for ICD-10 code E11.359 is crucial for accurate documentation, coding, and communication among healthcare providers. These terms not only facilitate clearer discussions about patient conditions but also ensure proper billing and coding practices in clinical settings. If you need further information on coding practices or related conditions, feel free to ask!

Diagnostic Criteria

The diagnosis of ICD-10 code E11.359, which refers to Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema, involves specific clinical criteria and assessments. Understanding these criteria is essential for accurate diagnosis and appropriate management of the condition.

Overview of Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is a severe form of diabetic eye disease characterized by the growth of new blood vessels in the retina, which can lead to vision loss. It typically occurs in individuals with long-standing diabetes and is associated with poor glycemic control. The absence of macular edema indicates that while there is significant retinal damage, the central part of the retina (the macula) is not swollen, which can help preserve central vision.

Diagnostic Criteria

1. Clinical History and Symptoms

  • Diabetes Diagnosis: A confirmed diagnosis of Type 2 diabetes mellitus (E11) is required. This is typically established through blood tests showing elevated glucose levels, such as fasting plasma glucose or HbA1c levels.
  • Duration of Diabetes: The risk of developing diabetic retinopathy increases with the duration of diabetes. Patients with Type 2 diabetes are often monitored for retinopathy after a few years of diagnosis.

2. Ophthalmic Examination

  • Fundoscopic Examination: A comprehensive eye examination, including a dilated fundoscopic exam, is crucial. The presence of retinal changes indicative of PDR, such as:
    • Neovascularization (new blood vessel growth)
    • Vitreous hemorrhage (bleeding into the vitreous cavity)
    • Retinal detachment (in severe cases)
  • Classification of Retinopathy: The diagnosis of PDR is confirmed when there is evidence of neovascularization without accompanying macular edema. This is assessed using standardized grading systems, such as the Early Treatment Diabetic Retinopathy Study (ETDRS) classification.

3. Exclusion of Macular Edema

  • Optical Coherence Tomography (OCT): This imaging test is often used to assess the presence of macular edema. In the case of E11.359, OCT results should show no significant swelling of the macula, which is critical for the diagnosis of proliferative diabetic retinopathy without macular edema.

4. Additional Tests

  • Fluorescein Angiography: This test may be performed to visualize blood flow in the retina and confirm the presence of neovascularization and to rule out other retinal conditions.
  • Visual Acuity Testing: While not directly related to the diagnosis of PDR, assessing visual acuity helps determine the impact of the retinopathy on the patient’s vision.

Conclusion

The diagnosis of ICD-10 code E11.359 requires a combination of clinical history, thorough ophthalmic examination, and imaging studies to confirm the presence of proliferative diabetic retinopathy while ensuring that macular edema is absent. Regular monitoring and early detection are crucial for managing diabetic retinopathy effectively and preventing vision loss. If you have further questions or need more detailed information on this topic, feel free to ask!

Treatment Guidelines

Proliferative diabetic retinopathy (PDR) is a serious complication of diabetes, particularly type 2 diabetes mellitus, and is classified under the ICD-10 code E11.359. This condition is characterized by the growth of new blood vessels in the retina, which can lead to vision loss if not treated effectively. Here, we will explore the standard treatment approaches for managing PDR without macular edema.

Understanding Proliferative Diabetic Retinopathy

PDR occurs when the retina becomes ischemic due to diabetes-related damage to blood vessels, prompting the formation of new, fragile blood vessels (neovascularization). These new vessels can bleed into the vitreous cavity, leading to severe vision impairment. The absence of macular edema in this context indicates that the central part of the retina is not swollen, which can influence treatment decisions.

Standard Treatment Approaches

1. Laser Photocoagulation Therapy

Laser photocoagulation is the primary treatment for PDR. This procedure involves using a laser to create small burns in the peripheral retina, which helps to reduce the oxygen demand of the retina and decrease the stimulus for neovascularization. The two main types of laser treatments are:

  • Panretinal Photocoagulation (PRP): This is the most common approach, where multiple laser spots are applied to the peripheral retina. PRP has been shown to significantly reduce the risk of severe vision loss in patients with PDR[1][2].

  • Focal Laser Treatment: While primarily used for macular edema, focal laser can also be applied in certain cases to target specific areas of neovascularization.

2. Anti-VEGF Injections

Anti-vascular endothelial growth factor (anti-VEGF) therapy has emerged as a significant treatment option for PDR. These medications, such as ranibizumab (Lucentis) and aflibercept (Eylea), inhibit the action of VEGF, a protein that promotes the growth of new blood vessels. Anti-VEGF injections can help reduce neovascularization and the risk of complications associated with PDR[3][4].

3. Vitrectomy

In cases where there is significant bleeding into the vitreous or if tractional retinal detachment occurs, a surgical procedure called vitrectomy may be necessary. This involves removing the vitreous gel and any scar tissue that may be pulling on the retina. Vitrectomy can improve visual outcomes in patients with advanced PDR[5].

4. Management of Diabetes

Effective management of diabetes is crucial in preventing the progression of diabetic retinopathy. This includes:

  • Glycemic Control: Maintaining optimal blood glucose levels through diet, exercise, and medication can slow the progression of diabetic retinopathy[6].

  • Blood Pressure and Lipid Management: Controlling hypertension and dyslipidemia is also important, as these factors can exacerbate retinal damage[7].

5. Regular Monitoring

Patients diagnosed with PDR should undergo regular eye examinations to monitor the progression of the disease. This typically includes dilated fundus examinations and optical coherence tomography (OCT) to assess retinal health and detect any changes early[8].

Conclusion

The management of proliferative diabetic retinopathy without macular edema involves a combination of laser therapy, anti-VEGF injections, and possibly surgical intervention, alongside rigorous control of diabetes and regular monitoring. Early detection and treatment are vital to preserving vision and preventing severe complications associated with this condition. Patients should work closely with their healthcare providers to develop a comprehensive treatment plan tailored to their specific needs.

References

  1. Diabetic Retinopathy Preferred Practice Pattern.
  2. Trends in the Prevalence and Treatment of Diabetic Macular Edema.
  3. Risk of diabetic retinopathy and diabetic macular oedema.
  4. Billing and Coding: Ophthalmology: Posterior Segment.
  5. Common Diabetes-related Eye Diseases & Their ICD-10.
  6. International Classification of Diseases, 10th Revision.
  7. International Classification of Diseases, 10th Revision, Coding.
  8. Fluorescein Angiography (L33997).

Description

Clinical Description of ICD-10 Code E11.359

ICD-10 Code E11.359 refers to a specific diagnosis within the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM). This code is used to classify Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema. Understanding this condition requires a closer look at both diabetes and its complications, particularly diabetic retinopathy.

Type 2 Diabetes Mellitus

Type 2 diabetes mellitus is a chronic condition characterized by insulin resistance and relative insulin deficiency. It is the most common form of diabetes, often associated with obesity, sedentary lifestyle, and genetic predisposition. Patients with Type 2 diabetes may experience a range of symptoms, including increased thirst, frequent urination, fatigue, and blurred vision. Long-term complications can affect various organ systems, particularly the eyes, kidneys, nerves, and cardiovascular system[6][8].

Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is a severe form of diabetic retinopathy, a complication of diabetes that affects the retina. In PDR, new blood vessels grow abnormally on the surface of the retina, a process known as neovascularization. This occurs in response to retinal ischemia (lack of blood flow) due to damage from high blood sugar levels. These new vessels are fragile and can lead to bleeding in the eye, potentially resulting in vision loss.

Without Macular Edema: The specification "without macular edema" indicates that, while the patient has proliferative diabetic retinopathy, there is no swelling in the macula, the central part of the retina responsible for sharp vision. Macular edema can occur in conjunction with diabetic retinopathy and is characterized by fluid accumulation in the macula, leading to blurred or distorted vision. The absence of macular edema in this diagnosis suggests that the patient's vision may not be as severely affected as it could be if edema were present[11][12].

Clinical Implications

Patients diagnosed with E11.359 may require regular monitoring and management to prevent progression of their condition. Key aspects of management include:

  • Blood Sugar Control: Maintaining optimal blood glucose levels is crucial to prevent further retinal damage and other complications.
  • Regular Eye Examinations: Patients should undergo comprehensive eye exams, including dilated fundus examinations, to monitor for changes in the retina.
  • Treatment Options: If neovascularization leads to complications, treatments such as laser photocoagulation or intravitreal injections (e.g., anti-VEGF therapy) may be necessary to manage the condition and preserve vision[10][14].

Conclusion

ICD-10 code E11.359 encapsulates a significant health concern for individuals with Type 2 diabetes, highlighting the importance of vigilant monitoring and proactive management of diabetic retinopathy. Understanding the nuances of this diagnosis can aid healthcare providers in delivering appropriate care and interventions to mitigate the risk of vision loss and improve overall patient outcomes. Regular follow-ups and adherence to diabetes management protocols are essential for patients diagnosed with this condition.

Related Information

Clinical Information

  • Elevated blood glucose levels
  • Insulin resistance and deficiency
  • Diabetic retinopathy complications
  • Proliferative diabetic retinopathy (PDR)
  • New abnormal blood vessels on retina
  • Retinal hemorrhages and exudates present
  • Visual disturbances and sudden vision loss
  • Long-standing diabetes history typical
  • Poor glycemic control increases risk
  • Age and comorbidities exacerbate risk

Approximate Synonyms

  • Type 2 Diabetes with Proliferative Diabetic Retinopathy
  • Proliferative Diabetic Retinopathy (PDR)
  • Diabetic Retinopathy without Macular Edema
  • Diabetes-Related Eye Disease
  • Retinal Neovascularization
  • Vision Loss due to Diabetes
  • Ophthalmic Complications of Diabetes

Diagnostic Criteria

  • Confirmed diagnosis of Type 2 diabetes mellitus
  • Duration of diabetes increases risk of retinopathy
  • Neovascularization in retina is present
  • Vitreous hemorrhage or retinal detachment may be present
  • Macular edema is absent as confirmed by OCT
  • Fluorescein angiography may be performed to confirm neovascularization
  • Visual acuity testing assesses impact on vision

Treatment Guidelines

  • Laser photocoagulation is primary treatment
  • Panretinal photocoagulation reduces severe vision loss
  • Focal laser targets specific neovascularization
  • Anti-VEGF injections reduce neovascularization
  • Vitrectomy removes bleeding or scar tissue
  • Glycemic control slows diabetic retinopathy progression
  • Blood pressure and lipid management prevent exacerbation

Description

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.