ICD-10: E67.3

Hypervitaminosis D, classified under ICD-10 code E67.3, refers to a condition resulting from excessive intake of vitamin D, leading to toxicity. Understanding its clinical presentation, signs, symptoms, and patient characteristics is crucial for effective diagnosis and management.

Clinical Presentation

Hypervitaminosis D typically arises from the overconsumption of vitamin D supplements rather than dietary sources or sun exposure, as the body regulates vitamin D synthesis from sunlight and food intake effectively. The clinical presentation can vary significantly based on the severity of the condition and the duration of vitamin D excess.

Signs and Symptoms

The symptoms of hypervitaminosis D can be categorized into acute and chronic manifestations:

Acute Symptoms

• Nausea and Vomiting: Patients may experience gastrointestinal distress, including nausea and vomiting, which can be severe in some cases.
• Weakness and Fatigue: Generalized weakness and fatigue are common, often leading to decreased physical activity.
• Dehydration: Due to vomiting and increased urination, dehydration can occur, resulting in further complications.

Chronic Symptoms

• Hypercalcemia: One of the most significant consequences of vitamin D toxicity is hypercalcemia (elevated calcium levels in the blood), which can lead to:
• Kidney Stones: Increased calcium levels can precipitate the formation of kidney stones.
• Renal Impairment: Prolonged hypercalcemia can cause damage to the kidneys, leading to renal failure.
• Bone Pain: Patients may report bone pain or discomfort due to altered calcium metabolism.
• Psychiatric Symptoms: Some individuals may experience confusion, disorientation, or other cognitive disturbances.

Patient Characteristics

Certain patient characteristics may predispose individuals to hypervitaminosis D:

• Supplement Use: Patients who take high doses of vitamin D supplements, often without medical supervision, are at increased risk. This is particularly common among individuals seeking to improve bone health or manage conditions like osteoporosis.
• Underlying Health Conditions: Individuals with certain health conditions, such as granulomatous diseases (e.g., sarcoidosis) or lymphoproliferative disorders, may be more susceptible to vitamin D toxicity due to altered metabolism.
• Age and Gender: While hypervitaminosis D can affect individuals of any age, older adults may be more vulnerable due to potential renal impairment and the common use of supplements. There is no significant gender predisposition noted in the literature.

Conclusion

Hypervitaminosis D is a serious condition that can lead to significant health complications if not recognized and managed promptly. Awareness of its clinical presentation, including the signs and symptoms associated with acute and chronic toxicity, is essential for healthcare providers. Additionally, understanding patient characteristics that may increase the risk of developing this condition can aid in prevention and early intervention strategies. Regular monitoring of vitamin D levels, especially in at-risk populations, is recommended to avoid the adverse effects associated with excessive vitamin D intake.

Hypervitaminosis D, classified under ICD-10 code E67.3, refers to a condition resulting from excessive intake of vitamin D, leading to toxicity. Understanding alternative names and related terms can enhance clarity in medical documentation and communication. Below are some alternative names and related terms associated with Hypervitaminosis D.

Alternative Names for Hypervitaminosis D

1. Vitamin D Toxicity: This term is commonly used to describe the adverse effects resulting from excessive vitamin D levels in the body.
2. Vitamin D Overdose: This phrase emphasizes the excessive intake aspect, often used in discussions about dietary supplements or medications.
3. Hypervitaminosis D Syndrome: This term may be used to describe the collection of symptoms and health issues arising from vitamin D toxicity.

Related Terms

1. Vitamin D: A fat-soluble vitamin essential for maintaining bone health and calcium metabolism, but can be harmful in excessive amounts.
2. Calcium Metabolism Disorders: Conditions that may arise due to altered calcium levels in the body, often linked to hypervitaminosis D.
3. Hypercalcemia: A condition characterized by elevated calcium levels in the blood, which can result from hypervitaminosis D.
4. Cholecalciferol Toxicity: Refers specifically to toxicity from vitamin D3, one of the forms of vitamin D.
5. Ergocalciferol Toxicity: This term pertains to toxicity from vitamin D2, another form of vitamin D.

Clinical Context

In clinical settings, it is crucial to differentiate between hypervitaminosis D and other conditions related to vitamin D metabolism. Accurate terminology aids in diagnosis, treatment planning, and coding for insurance purposes. The ICD-10 code E67.3 is specifically designated for cases of hypervitaminosis D, ensuring that healthcare providers can effectively communicate about this condition.

Understanding these alternative names and related terms can facilitate better patient education and enhance the accuracy of medical records, ultimately leading to improved patient care and outcomes.

Hypervitaminosis D, classified under ICD-10 code E67.3, refers to an excessive accumulation of vitamin D in the body, leading to toxicity. This condition can result from excessive supplementation, certain medical conditions, or, in rare cases, dietary sources. Understanding the standard treatment approaches for hypervitaminosis D is crucial for effective management and recovery.

Understanding Hypervitaminosis D

Causes

Hypervitaminosis D primarily occurs due to:
- Excessive Supplementation: The most common cause is the overconsumption of vitamin D supplements, often exceeding the recommended daily allowance significantly.
- Medical Conditions: Certain diseases, such as granulomatous disorders (e.g., sarcoidosis) or lymphomas, can increase the conversion of vitamin D to its active form, leading to toxicity.
- Dietary Sources: While rare, extremely high intake of vitamin D-rich foods can contribute to elevated levels.

Symptoms

Symptoms of hypervitaminosis D can include:
- Nausea and vomiting
- Weakness and fatigue
- Increased thirst and urination
- Confusion or disorientation
- Kidney stones or renal failure in severe cases

Standard Treatment Approaches

1. Discontinuation of Vitamin D Intake

The first step in managing hypervitaminosis D is to immediately stop all sources of vitamin D, including supplements and fortified foods. This cessation helps prevent further accumulation of the vitamin in the body.

2. Hydration and Electrolyte Management

Patients are often advised to increase fluid intake to help dilute serum calcium levels and promote renal excretion of excess calcium. In cases of severe hypercalcemia, intravenous fluids may be necessary to ensure adequate hydration and electrolyte balance.

3. Monitoring Serum Calcium Levels

Regular monitoring of serum calcium and vitamin D levels is essential. This helps assess the severity of hypervitaminosis D and guides further treatment decisions. Elevated calcium levels (hypercalcemia) can lead to serious complications, so close observation is critical.

4. Medications

In cases of significant hypercalcemia, medications may be required:
- Corticosteroids: These can help reduce calcium levels by inhibiting intestinal absorption and promoting renal excretion.
- Bisphosphonates: These drugs can be used to lower calcium levels by inhibiting bone resorption.
- Calcitonin: This hormone can also be administered to lower serum calcium levels.

5. Dialysis

In severe cases where hypercalcemia does not respond to medical management, dialysis may be necessary to remove excess calcium from the bloodstream.

6. Long-term Management

After acute management, patients should be educated about safe vitamin D levels and the importance of adhering to recommended dosages to prevent recurrence. Regular follow-up appointments may be necessary to monitor vitamin D and calcium levels.

Conclusion

Hypervitaminosis D is a serious condition that requires prompt recognition and management. The standard treatment approaches focus on discontinuing vitamin D intake, managing hydration and electrolyte levels, and monitoring serum calcium. In severe cases, medications or dialysis may be necessary. Education on safe vitamin D practices is crucial for preventing future occurrences. If you suspect hypervitaminosis D, it is essential to consult a healthcare professional for appropriate evaluation and treatment.

Hypervitaminosis D, classified under ICD-10 code E67.3, refers to a condition resulting from excessive intake of vitamin D, leading to toxic levels in the body. This condition can have significant health implications, primarily affecting calcium metabolism and leading to various systemic complications.

Clinical Description

Definition

Hypervitaminosis D occurs when there is an abnormally high level of vitamin D in the body, typically due to excessive supplementation rather than dietary intake or sun exposure. Vitamin D is crucial for calcium absorption and bone health, but in excessive amounts, it can lead to hypercalcemia (elevated calcium levels in the blood), which can cause various health issues.

Causes

The primary cause of hypervitaminosis D is the overconsumption of vitamin D supplements. It is important to note that this condition is rare and usually results from taking doses significantly higher than the recommended dietary allowance (RDA). Other potential causes may include:

• Certain medical conditions: Some diseases, such as granulomatous diseases (e.g., sarcoidosis), can increase the conversion of vitamin D to its active form, leading to elevated levels.
• Medications: Certain medications may affect vitamin D metabolism, contributing to toxicity.

Symptoms

Symptoms of hypervitaminosis D can vary widely and may include:

• Nausea and vomiting
• Weakness and fatigue
• Frequent urination
• Kidney stones
• Confusion or disorientation
• Bone pain
• Muscle weakness

In severe cases, hypervitaminosis D can lead to more serious complications, such as kidney damage or cardiovascular issues due to prolonged hypercalcemia.

Diagnosis

Diagnosis of hypervitaminosis D typically involves:

• Clinical evaluation: A thorough medical history and physical examination to assess symptoms and potential sources of excessive vitamin D intake.
• Laboratory tests: Blood tests to measure serum levels of vitamin D (25-hydroxyvitamin D) and calcium. Elevated levels of both can confirm the diagnosis.

Treatment

The management of hypervitaminosis D focuses on reducing vitamin D levels and addressing hypercalcemia. Treatment options may include:

• Discontinuation of vitamin D supplements: The first step is to stop any vitamin D supplementation.
• Hydration: Increased fluid intake can help promote renal excretion of excess calcium.
• Medications: In severe cases, medications such as corticosteroids or bisphosphonates may be used to lower calcium levels.

Conclusion

Hypervitaminosis D is a serious condition that arises from excessive vitamin D intake, leading to elevated calcium levels and various health complications. Awareness of the symptoms and causes is crucial for early diagnosis and effective management. Regular monitoring of vitamin D levels, especially in individuals taking supplements, can help prevent this condition and ensure optimal health outcomes.

Hypervitaminosis D, classified under ICD-10 code E67.3, refers to a condition resulting from excessive intake of vitamin D, leading to elevated levels of calcium in the blood (hypercalcemia) and various associated health issues. The diagnosis of hypervitaminosis D involves several criteria and considerations, which are outlined below.

Clinical Criteria for Diagnosis

1. Symptoms and Clinical Presentation

Patients with hypervitaminosis D may present with a range of symptoms, including:
- Nausea and vomiting
- Weakness and fatigue
- Increased thirst and urination
- Confusion or cognitive disturbances
- Abdominal pain
- Bone pain

These symptoms arise due to the effects of elevated calcium levels on various body systems, particularly the kidneys, gastrointestinal tract, and nervous system[1].

2. Laboratory Testing

Diagnosis typically involves laboratory tests to confirm elevated vitamin D levels and associated hypercalcemia:
- Serum 25-hydroxyvitamin D (25(OH)D) Levels: A serum level greater than 100 ng/mL (250 nmol/L) is often indicative of hypervitaminosis D[2].
- Serum Calcium Levels: Hypercalcemia is confirmed with serum calcium levels exceeding the normal range (typically >10.5 mg/dL or 2.65 mmol/L) and may be accompanied by elevated parathyroid hormone (PTH) levels[3].
- Phosphate Levels: Phosphate levels may also be assessed, as they can be affected by vitamin D metabolism.

3. Medical History

A thorough medical history is crucial in diagnosing hypervitaminosis D. Key aspects include:
- Supplement Intake: Documentation of vitamin D supplementation, including dosage and duration, is essential. High doses (often >4000 IU/day) over extended periods can lead to toxicity[4].
- Dietary Sources: Assessment of dietary intake of vitamin D-rich foods and fortified products.
- Underlying Conditions: Evaluation for conditions that may predispose individuals to vitamin D toxicity, such as granulomatous diseases (e.g., sarcoidosis) or certain lymphomas that can increase vitamin D metabolism[5].

4. Exclusion of Other Conditions

It is important to rule out other causes of hypercalcemia, such as:
- Primary hyperparathyroidism
- Malignancy
- Other metabolic disorders

This may involve additional testing, including imaging studies or further biochemical tests, to ensure an accurate diagnosis[6].

Conclusion

The diagnosis of hypervitaminosis D (ICD-10 code E67.3) is based on a combination of clinical symptoms, laboratory findings, and a detailed medical history. Elevated serum levels of vitamin D and calcium, along with a history of excessive vitamin D intake, are critical for confirming the diagnosis. Proper assessment and exclusion of other potential causes of hypercalcemia are also essential to ensure accurate diagnosis and management. If you suspect hypervitaminosis D, it is advisable to consult a healthcare professional for appropriate testing and evaluation.