ICD-10: F11.921

Opioid use, unspecified with intoxication delirium

Clinical Information

Inclusion Terms

  • Opioid-induced delirium

Additional Information

Clinical Information

The ICD-10 code F11.921 refers to "Opioid use, unspecified, with intoxication delirium." This diagnosis encompasses a range of clinical presentations, signs, symptoms, and patient characteristics associated with opioid intoxication leading to delirium. Below is a detailed overview of these aspects.

Clinical Presentation

Overview of Opioid Intoxication

Opioid intoxication occurs when an individual consumes opioids in amounts that exceed their tolerance, leading to various physiological and psychological effects. The severity of symptoms can vary based on the type of opioid used, the dosage, and the individual’s prior exposure to opioids.

Delirium

Delirium is characterized by an acute change in attention and cognition, often fluctuating in severity. In the context of opioid use, delirium can manifest as confusion, disorientation, and altered levels of consciousness.

Signs and Symptoms

Common Signs

  1. Altered Mental Status: Patients may exhibit confusion, disorientation, or an inability to focus.
  2. Drowsiness or Sedation: A hallmark of opioid intoxication is significant sedation, which can progress to stupor or coma.
  3. Respiratory Depression: Decreased respiratory rate and depth can occur, posing a risk of hypoxia.
  4. Pupil Changes: Miosis (constricted pupils) is commonly observed in opioid intoxication.
  5. Hypotension: Low blood pressure may be present due to the depressant effects of opioids.

Symptoms

  1. Cognitive Impairment: Difficulty in thinking clearly, memory disturbances, and impaired judgment.
  2. Hallucinations: Visual or auditory hallucinations may occur, contributing to the delirious state.
  3. Agitation or Restlessness: Some patients may exhibit agitation, particularly if they are in withdrawal or experiencing acute intoxication.
  4. Nausea and Vomiting: Gastrointestinal symptoms can accompany opioid use, especially in higher doses.

Patient Characteristics

Demographics

  • Age: Opioid use disorder can affect individuals across various age groups, but it is particularly prevalent among young adults and middle-aged individuals.
  • Gender: Males are more frequently diagnosed with opioid use disorders compared to females, although the gap is narrowing.

Risk Factors

  1. History of Substance Use: A personal or family history of substance use disorders increases the risk of opioid use and subsequent intoxication.
  2. Mental Health Disorders: Co-occurring mental health issues, such as depression or anxiety, are common among individuals with opioid use disorders.
  3. Chronic Pain Conditions: Many individuals with opioid use disorder initially use opioids for legitimate medical reasons, such as chronic pain management.

Comorbidities

Patients with opioid use disorder often present with other medical or psychiatric conditions, including:
- HIV/AIDS: Increased risk due to shared needle use.
- Hepatitis C: Common among individuals who inject opioids.
- Other Substance Use Disorders: Polysubstance use is prevalent, complicating the clinical picture.

Conclusion

The clinical presentation of opioid use with intoxication delirium (ICD-10 code F11.921) is complex, involving a range of signs and symptoms that reflect both the effects of opioids and the acute cognitive disturbances associated with delirium. Understanding these characteristics is crucial for healthcare providers to effectively diagnose and manage patients experiencing opioid intoxication. Early recognition and intervention can significantly improve outcomes for individuals affected by this condition.

Approximate Synonyms

ICD-10 code F11.921 refers to "Opioid use, unspecified, with intoxication delirium." This code is part of the broader classification of opioid-related disorders and is used to document cases where an individual is experiencing delirium due to opioid use, but the specific type of opioid is not specified.

  1. Opioid Intoxication: This term generally refers to the state of being under the influence of opioids, which can lead to various symptoms, including altered mental status and delirium.

  2. Opioid Use Disorder (OUD): While F11.921 specifically addresses intoxication with delirium, opioid use disorder encompasses a broader range of issues related to the misuse of opioids, including dependence and withdrawal.

  3. Delirium Due to Opioid Use: This phrase highlights the specific symptom of delirium that arises from opioid intoxication, emphasizing the cognitive and perceptual disturbances associated with the condition.

  4. Substance-Induced Delirium: This term can be used more generally to describe delirium caused by the use of substances, including opioids. It may not specify opioids but is relevant in the context of substance-related disorders.

  5. Opioid-Related Disorders: This broader category includes various conditions related to opioid use, including intoxication, dependence, and withdrawal syndromes.

  6. Acute Opioid Intoxication: This term can be used to describe a recent or sudden onset of symptoms due to opioid use, which may include delirium.

  7. Opioid Delirium: A more specific term that directly links opioid use to the state of delirium, often used in clinical settings to describe the condition.

Clinical Context

Understanding these alternative names and related terms is crucial for healthcare professionals when documenting and coding patient encounters. Accurate coding ensures appropriate treatment and management of patients experiencing complications from opioid use, particularly in emergency and psychiatric settings.

Conclusion

In summary, while F11.921 specifically denotes "Opioid use, unspecified, with intoxication delirium," various alternative names and related terms can be used to describe the condition and its implications. These terms are essential for effective communication among healthcare providers and for accurate medical documentation.

Description

ICD-10 code F11.921 refers to "Opioid use, unspecified, with intoxication delirium." This code is part of the broader classification of opioid-related disorders, which are categorized under the F11 codes in the ICD-10-CM (International Classification of Diseases, 10th Revision, Clinical Modification). Below is a detailed clinical description and relevant information regarding this diagnosis.

Clinical Description

Definition

The term "opioid use" encompasses the consumption of substances that act on the opioid receptors in the brain, which can include both prescription medications (like morphine, oxycodone, and hydrocodone) and illicit drugs (such as heroin). The "unspecified" designation indicates that the specific type of opioid used is not documented or is not relevant for the diagnosis.

Intoxication Delirium

Intoxication delirium refers to a state of confusion, altered consciousness, and cognitive impairment that occurs as a result of acute intoxication with opioids. This condition can manifest through various symptoms, including:

  • Altered mental status: Patients may exhibit confusion, disorientation, or an inability to focus.
  • Hallucinations: Visual or auditory hallucinations may occur, leading to further disorientation.
  • Mood changes: Intoxication can lead to significant mood swings, including agitation or euphoria.
  • Physical symptoms: These may include drowsiness, slurred speech, and impaired coordination.

Clinical Implications

The presence of intoxication delirium necessitates immediate medical attention, as it can lead to severe complications, including respiratory depression, coma, or even death. Treatment typically involves supportive care, monitoring of vital signs, and potentially the administration of opioid antagonists like naloxone to reverse the effects of opioid overdose.

Diagnostic Criteria

To assign the F11.921 code, the following criteria must generally be met:

  1. Evidence of Opioid Use: There must be a documented history of opioid use, which can be confirmed through patient self-report, prescription records, or toxicology screens.
  2. Symptoms of Intoxication Delirium: The patient must exhibit signs consistent with delirium, including cognitive impairment and altered consciousness, directly attributable to opioid use.
  3. Exclusion of Other Causes: It is essential to rule out other potential causes of delirium, such as infections, metabolic disturbances, or other substance use.

Treatment Considerations

Management of patients diagnosed with F11.921 typically involves:

  • Immediate Assessment: A thorough evaluation of the patient's mental status and vital signs.
  • Supportive Care: Ensuring the patient's safety and comfort, including hydration and monitoring for respiratory distress.
  • Pharmacological Interventions: Administering naloxone if opioid overdose is suspected, along with other medications as needed to manage symptoms of delirium.
  • Long-term Management: Once stabilized, addressing the underlying opioid use disorder through counseling, medication-assisted treatment (MAT), and support services.

Conclusion

ICD-10 code F11.921 is critical for identifying patients experiencing complications from opioid use, specifically those presenting with intoxication delirium. Accurate coding and diagnosis are essential for appropriate treatment and management, as well as for tracking the prevalence of opioid-related disorders in clinical settings. Understanding the clinical implications and treatment strategies associated with this diagnosis can significantly impact patient outcomes and healthcare resource allocation.

Diagnostic Criteria

The ICD-10 code F11.921 refers to "Opioid use, unspecified, with intoxication delirium." This diagnosis is part of the broader category of opioid-related disorders, which are classified under the F11 codes in the ICD-10-CM (International Classification of Diseases, 10th Revision, Clinical Modification). Understanding the criteria for diagnosing this condition involves several key components, including clinical features, diagnostic criteria, and the context of opioid use.

Diagnostic Criteria for Opioid Use Disorder

To diagnose opioid use disorder, including cases with intoxication delirium, healthcare providers typically refer to the criteria outlined in the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition). The following criteria are relevant:

  1. Impaired Control: The individual may take opioids in larger amounts or over a longer period than intended, express a persistent desire to cut down or control use, or spend a significant amount of time obtaining, using, or recovering from the effects of opioids.

  2. Social Impairment: Continued use despite having persistent social or interpersonal problems caused or exacerbated by the effects of opioids, such as neglecting responsibilities at work, school, or home.

  3. Risky Use: Recurrent use in situations where it is physically hazardous, such as driving under the influence.

  4. Pharmacological Criteria: Tolerance (requiring increased amounts to achieve intoxication or diminished effect with continued use) and withdrawal symptoms, which can be relieved by taking opioids.

  5. Severity: The diagnosis can be classified as mild, moderate, or severe based on the number of criteria met (2-3 for mild, 4-5 for moderate, and 6 or more for severe).

Intoxication Delirium

For the specific diagnosis of F11.921, the presence of intoxication delirium is crucial. This condition is characterized by:

  • Altered Mental Status: The individual may exhibit confusion, disorientation, or impaired judgment.
  • Behavioral Changes: This can include agitation, aggression, or other significant changes in behavior.
  • Cognitive Impairment: Difficulty with attention, memory, and other cognitive functions.

The delirium must be directly attributable to the effects of opioid use, distinguishing it from other potential causes of delirium, such as medical conditions or other substance use.

Clinical Assessment

When assessing for F11.921, clinicians typically conduct a thorough evaluation that includes:

  • Patient History: Gathering information about the patient's opioid use, including types of opioids used, duration, and patterns of use.
  • Physical Examination: Assessing for signs of intoxication, such as respiratory depression, pinpoint pupils, or altered consciousness.
  • Mental Status Examination: Evaluating cognitive function and behavior to identify signs of delirium.

Conclusion

In summary, the diagnosis of F11.921 (Opioid use, unspecified, with intoxication delirium) requires a comprehensive assessment that includes the criteria for opioid use disorder and specific signs of delirium related to opioid intoxication. Clinicians must carefully evaluate the patient's history, conduct a physical examination, and assess mental status to ensure an accurate diagnosis and appropriate treatment plan. This approach is essential for managing the complexities associated with opioid use and its effects on mental health.

Treatment Guidelines

Opioid use disorder (OUD) is a significant public health concern, particularly when it involves complications such as intoxication delirium. The ICD-10 code F11.921 specifically refers to "Opioid use, unspecified, with intoxication delirium." This condition requires a comprehensive treatment approach that addresses both the immediate symptoms of intoxication and the underlying substance use disorder. Below, we explore standard treatment approaches for this condition.

Understanding Opioid Intoxication Delirium

Opioid intoxication can lead to a range of symptoms, including altered mental status, confusion, and delirium. Delirium is characterized by an acute change in attention and cognition, which can be exacerbated by the sedative effects of opioids. The management of this condition is critical, as it can lead to severe complications, including respiratory depression and increased risk of overdose.

Immediate Management of Intoxication

1. Emergency Care

  • Assessment: Initial evaluation should include a thorough assessment of the patient's vital signs, level of consciousness, and any potential co-ingestants.
  • Airway Management: Ensuring the airway is patent is crucial, especially if the patient is experiencing respiratory depression.
  • Naloxone Administration: Naloxone (Narcan) is an opioid antagonist that can rapidly reverse the effects of opioid overdose. It should be administered if opioid intoxication is suspected, particularly if the patient exhibits respiratory distress or altered mental status[1].

2. Supportive Care

  • Monitoring: Continuous monitoring of vital signs and mental status is essential. Patients may require hospitalization for close observation, especially if they are at risk for respiratory failure.
  • Hydration and Nutrition: Providing intravenous fluids may be necessary to maintain hydration, especially if the patient is unable to eat or drink due to altered mental status[2].

Long-term Treatment Approaches for Opioid Use Disorder

Once the acute phase of intoxication is managed, it is vital to address the underlying opioid use disorder. This typically involves a combination of pharmacological and psychosocial interventions.

1. Medication-Assisted Treatment (MAT)

  • Buprenorphine: This partial opioid agonist can help reduce cravings and withdrawal symptoms. It is often used in outpatient settings and can be prescribed by certified providers[3].
  • Methadone: A full opioid agonist, methadone is used in specialized treatment programs and can help stabilize patients with OUD.
  • Naltrexone: An opioid antagonist that can be used after detoxification to prevent relapse. It is not suitable for patients currently using opioids due to the risk of precipitated withdrawal[4].

2. Psychosocial Interventions

  • Counseling and Behavioral Therapies: Cognitive-behavioral therapy (CBT), contingency management, and motivational interviewing are effective in addressing the psychological aspects of addiction.
  • Support Groups: Participation in support groups such as Narcotics Anonymous (NA) can provide ongoing support and accountability for individuals in recovery[5].

3. Integrated Care Approaches

  • Co-occurring Disorders: Many individuals with OUD may also have co-occurring mental health disorders. Integrated treatment that addresses both substance use and mental health issues is crucial for effective recovery.
  • Case Management: Coordinating care through case management can help ensure that patients receive comprehensive services, including medical, psychological, and social support[6].

Conclusion

The treatment of opioid use disorder with intoxication delirium (ICD-10 code F11.921) requires a multifaceted approach that begins with immediate medical intervention to manage intoxication and progresses to long-term strategies aimed at recovery from substance use disorder. By combining emergency care, medication-assisted treatment, and psychosocial support, healthcare providers can significantly improve outcomes for individuals struggling with opioid use disorder. Continuous monitoring and integrated care are essential to address the complexities of this condition effectively.


References

  1. Emergency care protocols for opioid overdose management.
  2. Importance of hydration and nutrition in acute care settings.
  3. Overview of medication-assisted treatment options for opioid use disorder.
  4. Role of naltrexone in preventing relapse after detoxification.
  5. Benefits of support groups in recovery from substance use disorders.
  6. Integrated care approaches for co-occurring disorders in addiction treatment.

Related Information

Clinical Information

  • Altered mental status
  • Drowsiness or sedation
  • Respiratory depression
  • Pupil changes
  • Hypotension
  • Cognitive impairment
  • Hallucinations
  • Agitation or restlessness
  • Nausea and vomiting
  • Acute change in attention and cognition

Approximate Synonyms

  • Opioid Intoxication
  • Opioid Use Disorder (OUD)
  • Delirium Due to Opioid Use
  • Substance-Induced Delirium
  • Opioid-Related Disorders
  • Acute Opioid Intoxication
  • Opioid Delirium

Description

Diagnostic Criteria

  • Impaired control over opioid use
  • Persistent desire to cut down or control use
  • Spend significant time obtaining, using, or recovering from opioids
  • Continued use despite social problems caused by opioids
  • Recurrent use in physically hazardous situations
  • Tolerance requiring increased amounts of opioids
  • Withdrawal symptoms relieved by taking opioids
  • Altered mental status due to opioid intoxication
  • Behavioral changes such as agitation or aggression
  • Cognitive impairment including difficulty with attention and memory

Treatment Guidelines

  • Administer Naloxone to reverse opioid overdose
  • Ensure airway management and oxygenation
  • Monitor vital signs and mental status closely
  • Provide hydration and nutrition support
  • Use buprenorphine or methadone for medication-assisted treatment
  • Prescribe naltrexone after detoxification to prevent relapse
  • Offer counseling, behavioral therapies, and support groups
  • Coordinate care through case management for integrated treatment

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