ICD-10: H35.2

Other non-diabetic proliferative retinopathy

Clinical Information

Inclusion Terms

  • Thalassemia proliferative retinopathy
  • Proliferative vitreo-retinopathy

Additional Information

Description

ICD-10 code H35.2 refers to "Other non-diabetic proliferative retinopathy," a condition characterized by abnormal growth of blood vessels in the retina that is not associated with diabetes mellitus. This condition can lead to significant vision impairment if not diagnosed and treated promptly. Below is a detailed overview of the clinical description, causes, symptoms, diagnosis, and treatment options for this condition.

Clinical Description

Definition

Proliferative retinopathy is a term used to describe a group of retinal disorders where new, abnormal blood vessels grow in the retina. In the case of H35.2, these changes occur independently of diabetes, distinguishing it from diabetic retinopathy, which is a common complication of diabetes.

Pathophysiology

The abnormal blood vessel growth in proliferative retinopathy can result from various underlying conditions, including retinal vein occlusion, hypertension, or other systemic diseases. The new vessels are fragile and prone to bleeding, which can lead to complications such as vitreous hemorrhage and retinal detachment.

Causes

While the exact cause of non-diabetic proliferative retinopathy can vary, several factors may contribute to its development:

  • Retinal Vein Occlusion: Blockage of the veins in the retina can lead to increased pressure and subsequent abnormal vessel growth.
  • Hypertension: High blood pressure can damage the retinal blood vessels, promoting the development of proliferative changes.
  • Other Systemic Conditions: Conditions such as sickle cell disease or certain inflammatory diseases can also lead to proliferative retinopathy.

Symptoms

Patients with H35.2 may experience a range of symptoms, which can vary in severity:

  • Visual Disturbances: Blurred vision or sudden changes in vision may occur.
  • Floaters: Patients may notice spots or floaters in their field of vision, often due to bleeding from the abnormal vessels.
  • Dark Shadows: Some may experience dark areas in their vision, indicating potential retinal detachment.

Diagnosis

Diagnosis of non-diabetic proliferative retinopathy typically involves:

  • Comprehensive Eye Examination: An ophthalmologist will perform a thorough examination, including visual acuity tests and a dilated fundus examination to assess the retina.
  • Fluorescein Angiography: This imaging technique helps visualize the blood vessels in the retina and can identify areas of leakage or abnormal growth.
  • Optical Coherence Tomography (OCT): This non-invasive imaging test provides cross-sectional images of the retina, helping to assess the extent of the disease.

Treatment Options

Treatment for H35.2 focuses on managing the underlying causes and preventing complications:

  • Laser Photocoagulation: This procedure uses laser energy to target and destroy abnormal blood vessels, reducing the risk of bleeding and vision loss.
  • Anti-VEGF Injections: Medications that inhibit vascular endothelial growth factor (VEGF) can help reduce the growth of abnormal vessels and improve vision.
  • Surgery: In cases of significant bleeding or retinal detachment, surgical intervention may be necessary to repair the retina or remove blood from the vitreous cavity.

Conclusion

ICD-10 code H35.2 encompasses a critical area of ophthalmology concerning non-diabetic proliferative retinopathy. Understanding its clinical features, causes, symptoms, and treatment options is essential for timely diagnosis and management, ultimately aiming to preserve vision and improve patient outcomes. Regular eye examinations and monitoring for individuals at risk are vital components of care in preventing the progression of this condition.

Approximate Synonyms

ICD-10 code H35.2 refers to "Other non-diabetic proliferative retinopathy," a classification used in medical coding to identify specific types of retinal diseases that do not stem from diabetes. Understanding alternative names and related terms for this condition can enhance clarity in medical documentation and communication. Below are some alternative names and related terms associated with H35.2.

Alternative Names for H35.2

  1. Non-Diabetic Retinopathy: This term broadly encompasses retinal conditions that are not caused by diabetes, including various forms of proliferative retinopathy.

  2. Proliferative Retinopathy: While this term can refer to any proliferative changes in the retina, it is often used in the context of non-diabetic conditions when specified.

  3. Retinal Neovascularization: This term describes the formation of new blood vessels in the retina, which is a hallmark of proliferative retinopathy, regardless of the underlying cause.

  4. Retinal Vascular Disease: A broader category that includes various diseases affecting the retinal blood vessels, including non-diabetic proliferative conditions.

  5. Other Retinal Disorders: This term may be used in a more general sense to describe various retinal conditions that do not fit into specific categories, including H35.2.

  1. Vitreoretinal Disorders: This term encompasses diseases affecting both the vitreous and the retina, which can include non-diabetic proliferative retinopathy.

  2. Chorioretinal Disorders: Referring to diseases affecting both the choroid and retina, this term can sometimes overlap with conditions classified under H35.2.

  3. Retinal Ischemia: A condition that can lead to proliferative changes in the retina due to insufficient blood supply, relevant in the context of non-diabetic retinopathy.

  4. Retinal Hemorrhage: This term describes bleeding within the retina, which can occur in various types of retinopathy, including non-diabetic forms.

  5. Exudative Retinopathy: A term that may be used to describe retinal conditions characterized by the leakage of fluid or proteins, which can be associated with proliferative changes.

Conclusion

Understanding the alternative names and related terms for ICD-10 code H35.2 is essential for accurate medical coding, documentation, and communication among healthcare professionals. These terms help in identifying and discussing the various aspects of non-diabetic proliferative retinopathy, ensuring that patients receive appropriate care and treatment. If you need further information or specific details about related conditions, feel free to ask!

Treatment Guidelines

When addressing the standard treatment approaches for ICD-10 code H35.2, which refers to "Other non-diabetic proliferative retinopathy," it is essential to understand the underlying conditions and the available therapeutic options. Non-diabetic proliferative retinopathy can arise from various causes, including retinal vein occlusion, hypertension, and other systemic diseases. Here’s a detailed overview of the treatment strategies typically employed.

Understanding Non-Diabetic Proliferative Retinopathy

Non-diabetic proliferative retinopathy encompasses a range of retinal disorders characterized by the growth of new blood vessels (neovascularization) in the retina, which can lead to vision impairment or loss. The conditions leading to this type of retinopathy may include:

  • Retinal Vein Occlusion (RVO): Blockage of the veins carrying blood away from the retina.
  • Hypertensive Retinopathy: Damage to the retina due to high blood pressure.
  • Other Vascular Disorders: Conditions that affect blood flow to the retina.

Standard Treatment Approaches

1. Laser Photocoagulation

Laser photocoagulation is a primary treatment modality for managing proliferative retinopathy. This procedure involves using a laser to create small burns in the retina, which helps to:

  • Reduce the growth of abnormal blood vessels.
  • Prevent further bleeding and fluid leakage.
  • Stabilize vision by addressing the neovascularization process.

2. Anti-VEGF Therapy

Anti-vascular endothelial growth factor (anti-VEGF) injections are increasingly used to treat conditions associated with non-diabetic proliferative retinopathy. These medications work by inhibiting the action of VEGF, a protein that promotes the growth of new blood vessels. Commonly used anti-VEGF agents include:

  • Aflibercept (Eylea)
  • Ranibizumab (Lucentis)
  • Bevacizumab (Avastin)

These injections can help reduce retinal swelling and improve visual acuity by targeting the underlying neovascularization.

3. Corticosteroids

In some cases, corticosteroids may be administered either as injections or implants to reduce inflammation and edema in the retina. This approach can be particularly beneficial in cases where there is significant macular edema associated with the proliferative changes.

4. Surgical Interventions

For advanced cases where there is significant retinal detachment or hemorrhage, surgical options may be considered. These can include:

  • Vitrectomy: A surgical procedure to remove the vitreous gel from the eye, which may be necessary if there is bleeding or traction on the retina.
  • Scleral Buckling: A technique used to repair retinal detachments by indenting the wall of the eye.

5. Management of Underlying Conditions

Addressing systemic conditions that contribute to proliferative retinopathy is crucial. This may involve:

  • Controlling Blood Pressure: Effective management of hypertension can help prevent further retinal damage.
  • Managing Hyperlipidemia: Statins and other lipid-lowering agents may be prescribed to improve overall vascular health.

6. Regular Monitoring and Follow-Up

Patients diagnosed with non-diabetic proliferative retinopathy require regular follow-up appointments to monitor the progression of the disease and the effectiveness of treatments. This may include:

  • Ophthalmic Examinations: Regular dilated eye exams to assess retinal health.
  • Fluorescein Angiography: A diagnostic test to visualize blood flow in the retina and identify areas of leakage or neovascularization.

Conclusion

The management of ICD-10 code H35.2, or other non-diabetic proliferative retinopathy, involves a multifaceted approach that includes laser therapy, anti-VEGF injections, corticosteroids, and surgical interventions when necessary. Additionally, controlling underlying systemic conditions is vital for preventing disease progression. Regular monitoring is essential to ensure optimal outcomes and preserve vision. As research continues, new therapies may emerge, enhancing the treatment landscape for patients with this condition.

Clinical Information

The ICD-10 code H35.2 refers to "Other non-diabetic proliferative retinopathy," a condition characterized by abnormal growth of blood vessels in the retina that is not associated with diabetes. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for accurate diagnosis and management.

Clinical Presentation

Overview

Non-diabetic proliferative retinopathy can occur due to various underlying conditions, including retinal vein occlusion, hypertension, and other systemic diseases. The clinical presentation may vary depending on the underlying cause and the extent of retinal damage.

Signs and Symptoms

Patients with H35.2 may exhibit a range of signs and symptoms, which can include:

  • Visual Disturbances: Patients often report blurred vision, which may be sudden or gradual. In some cases, they may experience vision loss, particularly if the condition progresses to more severe stages.
  • Floaters: The presence of floaters or spots in the visual field is common, often resulting from the detachment of the vitreous gel from the retina.
  • Scotomas: Patients may notice blind spots or areas of reduced vision, which can be indicative of retinal damage.
  • Photopsia: Some individuals may experience flashes of light, a phenomenon that can occur due to retinal irritation or detachment.

Fundoscopic Findings

During an eye examination, specific findings may be observed, including:

  • Neovascularization: The formation of new, abnormal blood vessels on the surface of the retina or optic disc.
  • Hemorrhages: Presence of retinal hemorrhages, which can be flame-shaped or dot-and-blot types, indicating vascular leakage or rupture.
  • Exudates: Cotton wool spots and hard exudates may be present, reflecting retinal ischemia and damage.

Patient Characteristics

Demographics

  • Age: Non-diabetic proliferative retinopathy can affect individuals across various age groups, but it is more commonly seen in older adults due to age-related vascular changes.
  • Gender: There may be a slight male predominance in certain types of non-diabetic retinopathy, although this can vary based on the underlying cause.

Risk Factors

Several risk factors are associated with the development of H35.2, including:

  • Hypertension: Chronic high blood pressure is a significant risk factor for retinal vascular changes.
  • Hyperlipidemia: Elevated cholesterol levels can contribute to retinal vascular disease.
  • Systemic Diseases: Conditions such as autoimmune diseases, sickle cell disease, and certain infections can predispose individuals to proliferative retinopathy.
  • Smoking: Tobacco use is linked to various ocular diseases, including retinal disorders.

Comorbidities

Patients with non-diabetic proliferative retinopathy may often have comorbid conditions that exacerbate their ocular health, such as:

  • Cardiovascular Disease: Increased risk of heart disease and stroke can correlate with retinal vascular issues.
  • Chronic Kidney Disease: Renal impairment can lead to systemic changes that affect retinal health.

Conclusion

Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with ICD-10 code H35.2 is essential for healthcare providers. Early detection and management of non-diabetic proliferative retinopathy can help prevent significant vision loss and improve patient outcomes. Regular eye examinations and monitoring of risk factors are crucial for individuals at risk of developing this condition.

Diagnostic Criteria

The ICD-10 code H35.2 refers to "Other non-diabetic proliferative retinopathy," which encompasses a range of retinal conditions that lead to abnormal blood vessel growth in the retina but are not associated with diabetes. Understanding the criteria for diagnosing this condition is essential for accurate coding and treatment.

Diagnostic Criteria for H35.2

Clinical Evaluation

  1. Patient History: A thorough medical history is crucial. The clinician should assess for any underlying conditions that may contribute to proliferative retinopathy, such as hypertension, vascular diseases, or systemic inflammatory disorders.

  2. Symptoms: Patients may report symptoms such as blurred vision, floaters, or sudden vision loss. These symptoms can indicate retinal changes that warrant further investigation.

Ophthalmic Examination

  1. Fundoscopy: A dilated fundoscopic examination is performed to visualize the retina. The presence of neovascularization (new, abnormal blood vessels) is a key indicator of proliferative retinopathy.

  2. Retinal Imaging: Advanced imaging techniques, such as Optical Coherence Tomography (OCT) or fluorescein angiography, may be utilized to assess the extent of retinal damage and the presence of neovascularization. These imaging modalities provide detailed views of the retinal layers and blood flow.

Differential Diagnosis

  1. Exclusion of Diabetic Retinopathy: It is essential to rule out diabetic retinopathy, as this condition is the most common cause of proliferative changes in the retina. This can be done through a review of the patient's medical history and blood glucose levels.

  2. Other Causes: The clinician should consider other potential causes of proliferative retinopathy, such as:
    - Retinal vein occlusion: Blockage of the veins in the retina can lead to similar proliferative changes.
    - Hypertensive retinopathy: Chronic high blood pressure can cause changes in the retinal vasculature.
    - Sickle cell retinopathy: This condition can also lead to neovascularization due to abnormal blood flow.

Laboratory Tests

  1. Blood Tests: While not always necessary, blood tests may be conducted to evaluate systemic conditions that could contribute to retinal changes, such as blood glucose levels, lipid profiles, and inflammatory markers.

  2. Imaging Studies: In some cases, additional imaging studies may be warranted to assess for systemic vascular conditions that could impact retinal health.

Conclusion

The diagnosis of H35.2: Other non-diabetic proliferative retinopathy involves a comprehensive approach that includes patient history, clinical symptoms, detailed ophthalmic examination, and exclusion of other conditions, particularly diabetic retinopathy. Accurate diagnosis is crucial for effective management and treatment of the underlying causes of proliferative retinopathy, ensuring that patients receive appropriate care tailored to their specific needs.

Related Information

Description

  • Abnormal blood vessel growth in retina
  • Not associated with diabetes mellitus
  • Can lead to significant vision impairment
  • Proliferative retinopathy without diabetes
  • New vessels are fragile and prone to bleeding
  • Complications include vitreous hemorrhage and detachment

Approximate Synonyms

  • Non-Diabetic Retinopathy
  • Proliferative Retinopathy
  • Retinal Neovascularization
  • Retinal Vascular Disease
  • Other Retinal Disorders
  • Vitreoretinal Disorders
  • Chorioretinal Disorders
  • Retinal Ischemia
  • Retinal Hemorrhage
  • Exudative Retinopathy

Treatment Guidelines

  • Laser photocoagulation reduces abnormal blood vessel growth
  • Anti-VEGF therapy inhibits VEGF protein action
  • Corticosteroids reduce inflammation and edema
  • Vitrectomy removes vitreous gel from the eye
  • Scleral buckling repairs retinal detachments
  • Controlling hypertension prevents further damage
  • Managing hyperlipidemia improves vascular health

Clinical Information

Diagnostic Criteria

Coding Guidelines

Excludes 1

  • proliferative vitreo-retinopathy with retinal detachment (H33.4-)

Excludes 2

  • proliferative sickle-cell retinopathy (H36.82-)

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.