ICD-10: H40.141

Capsular glaucoma with pseudoexfoliation of lens, right eye

Additional Information

Description

Capsular glaucoma, specifically coded as ICD-10 code H40.141, refers to a type of glaucoma that occurs in conjunction with pseudoexfoliation syndrome affecting the lens of the eye. This condition is characterized by the accumulation of flaky, dandruff-like material on the lens and other structures within the eye, which can lead to increased intraocular pressure (IOP) and subsequent optic nerve damage if left untreated.

Clinical Description

Definition

Capsular glaucoma with pseudoexfoliation of the lens is a secondary form of glaucoma. It arises when the pseudoexfoliative material obstructs the trabecular meshwork, the drainage system of the eye, leading to elevated IOP. This condition is particularly noted in the right eye in this specific coding context.

Etiology

The exact cause of pseudoexfoliation syndrome is not fully understood, but it is associated with aging and is more prevalent in certain populations. The material produced can lead to mechanical obstruction and inflammation, contributing to the development of glaucoma.

Symptoms

Patients with capsular glaucoma may experience:
- Blurred vision
- Halos around lights
- Eye pain or discomfort
- Headaches
- Sudden vision changes, particularly in advanced stages

Diagnosis

Diagnosis typically involves:
- Comprehensive eye examination
- Measurement of intraocular pressure
- Assessment of the optic nerve for damage
- Gonioscopy to evaluate the drainage angle of the eye
- Slit-lamp examination to identify the presence of pseudoexfoliative material

Treatment

Management of capsular glaucoma with pseudoexfoliation may include:
- Medications: Topical eye drops to lower IOP, such as prostaglandin analogs, beta-blockers, or carbonic anhydrase inhibitors.
- Laser Therapy: Procedures like laser peripheral iridotomy or laser trabeculoplasty may be employed to improve aqueous outflow.
- Surgical Intervention: In cases where medications and laser treatments are insufficient, surgical options such as trabeculectomy or the implantation of drainage devices may be considered.

Coding Specifics

The ICD-10 code H40.141 specifically denotes capsular glaucoma associated with pseudoexfoliation of the lens in the right eye. This coding is crucial for accurate medical billing and documentation, ensuring that healthcare providers can effectively communicate the patient's condition for treatment and insurance purposes.

  • H40.140: Capsular glaucoma with pseudoexfoliation of lens, unspecified eye.
  • H40.142: Capsular glaucoma with pseudoexfoliation of lens, left eye.

Conclusion

Understanding the clinical implications of ICD-10 code H40.141 is essential for healthcare providers managing patients with this condition. Early diagnosis and appropriate treatment are critical to prevent vision loss associated with capsular glaucoma. Regular monitoring and follow-up care are also vital to ensure optimal management of intraocular pressure and overall eye health.

Clinical Information

Capsular glaucoma with pseudoexfoliation of the lens, classified under ICD-10 code H40.141, is a specific type of glaucoma that arises due to the presence of pseudoexfoliation syndrome (PEX). This condition is characterized by the accumulation of flaky, white material on the lens and other structures in the eye, which can lead to increased intraocular pressure (IOP) and subsequent optic nerve damage. Below is a detailed overview of the clinical presentation, signs, symptoms, and patient characteristics associated with this condition.

Clinical Presentation

Definition and Pathophysiology

Capsular glaucoma with pseudoexfoliation occurs when the pseudoexfoliative material leads to obstruction of the trabecular meshwork, resulting in impaired aqueous humor outflow. This can cause a significant rise in intraocular pressure, which is detrimental to the optic nerve and can lead to vision loss if not managed appropriately[1].

Patient Characteristics

Patients typically affected by capsular glaucoma with pseudoexfoliation are often older adults, as pseudoexfoliation syndrome is more prevalent in individuals over the age of 60. There is also a noted higher incidence in certain populations, particularly those of Scandinavian descent[2].

Signs and Symptoms

Common Symptoms

  1. Visual Disturbances: Patients may experience blurred vision, particularly in the later stages of the disease. This can be due to increased IOP or damage to the optic nerve.
  2. Halos Around Lights: Patients often report seeing halos around lights, especially at night, which can be attributed to corneal edema or changes in the lens.
  3. Eye Pain or Discomfort: Some patients may experience ocular pain, which can range from mild discomfort to severe pain, particularly during acute episodes of elevated IOP.
  4. Headaches: Increased intraocular pressure can lead to headaches, particularly in the frontal region.

Clinical Signs

  1. Increased Intraocular Pressure: Measurement of IOP will typically reveal elevated levels, often exceeding 21 mmHg, which is considered the threshold for glaucoma.
  2. Optic Nerve Changes: Fundoscopic examination may reveal characteristic changes in the optic nerve head, such as cupping, which indicates damage due to glaucoma.
  3. Pupil Reaction: The pupil may be irregularly shaped or non-reactive due to the effects of pseudoexfoliation on the iris and surrounding structures.
  4. Corneal Changes: The presence of pseudoexfoliative material can lead to corneal changes, including deposits on the corneal endothelium.

Additional Considerations

Patients with capsular glaucoma may also have a family history of glaucoma, which can increase their risk. Furthermore, those with systemic conditions such as hypertension or diabetes may be at a higher risk for developing glaucoma due to the associated vascular changes[3].

Conclusion

Capsular glaucoma with pseudoexfoliation of the lens (ICD-10 code H40.141) is a significant ocular condition primarily affecting older adults, characterized by increased intraocular pressure and potential optic nerve damage. Early detection and management are crucial to prevent irreversible vision loss. Regular eye examinations, particularly for those at risk, are essential for monitoring and managing this condition effectively. If you suspect you or someone you know may be experiencing symptoms related to this condition, it is important to seek evaluation from an eye care professional.

References

  1. ICD-10 Glaucoma Reference Guide.
  2. Analysis of genetically determined gene expression in relation to glaucoma.
  3. Primary Angle-Closure Disease Preferred Practice Pattern.

Approximate Synonyms

ICD-10 code H40.141 specifically refers to "Capsular glaucoma with pseudoexfoliation of lens, right eye." This condition is a type of glaucoma characterized by increased intraocular pressure due to the presence of pseudoexfoliation material, which can lead to damage to the optic nerve and vision loss. Below are alternative names and related terms associated with this condition:

Alternative Names

  1. Pseudoexfoliative Glaucoma: This term is often used interchangeably with capsular glaucoma when pseudoexfoliation is present.
  2. Exfoliative Glaucoma: A broader term that encompasses various forms of glaucoma associated with exfoliation syndrome.
  3. Secondary Glaucoma: Since capsular glaucoma arises due to another condition (pseudoexfoliation), it can be classified as secondary glaucoma.
  1. Pseudoexfoliation Syndrome (PXF): A systemic condition characterized by the production of flaky, dandruff-like material that can accumulate in the eye, leading to complications such as glaucoma.
  2. Intraocular Pressure (IOP): A critical measurement in diagnosing and managing glaucoma, often elevated in cases of capsular glaucoma.
  3. Optic Nerve Damage: A potential consequence of untreated glaucoma, including capsular glaucoma, which can lead to vision impairment.
  4. Visual Field Loss: A common symptom associated with glaucoma, including capsular glaucoma, where peripheral vision may be affected.
  5. Glaucoma Suspect: A term used for individuals who may be at risk for developing glaucoma due to factors such as elevated IOP or optic nerve changes.

Clinical Context

Understanding these alternative names and related terms is essential for healthcare professionals involved in the diagnosis and treatment of glaucoma. Accurate coding and terminology are crucial for effective communication among medical practitioners and for proper billing and insurance purposes.

In summary, H40.141 is closely linked to various terms that reflect its clinical implications and associations with pseudoexfoliation syndrome. Recognizing these terms can enhance understanding and management of the condition.

Diagnostic Criteria

The diagnosis of capsular glaucoma with pseudoexfoliation of the lens, specifically coded as ICD-10 H40.141, involves a combination of clinical findings, patient history, and specific diagnostic criteria. Below is a detailed overview of the criteria used for this diagnosis.

Understanding Capsular Glaucoma and Pseudoexfoliation

Capsular Glaucoma

Capsular glaucoma refers to a type of secondary glaucoma that occurs due to the presence of a lens capsule or other material obstructing the outflow of aqueous humor, leading to increased intraocular pressure (IOP). This condition can result in optic nerve damage and vision loss if not managed appropriately.

Pseudoexfoliation Syndrome

Pseudoexfoliation syndrome is characterized by the accumulation of flaky, white material on the lens and other structures within the eye. This material can lead to various complications, including capsular glaucoma, as it may obstruct the drainage pathways of the eye.

Diagnostic Criteria for ICD-10 H40.141

1. Clinical Examination

  • Intraocular Pressure Measurement: Elevated IOP is a primary indicator of glaucoma. Normal IOP ranges from 10 to 21 mmHg; values above this range may suggest glaucoma.
  • Visual Field Testing: Assessing the visual field can help identify any peripheral vision loss, which is common in glaucoma patients.
  • Optic Nerve Assessment: Examination of the optic nerve head for cupping or other signs of damage is crucial. This can be done using techniques such as fundus photography or optical coherence tomography (OCT).

2. History of Pseudoexfoliation

  • A documented history of pseudoexfoliation syndrome is essential. This may include previous diagnoses or findings of pseudoexfoliative material during slit-lamp examination.

3. Slit-Lamp Examination

  • A thorough slit-lamp examination is necessary to identify the presence of pseudoexfoliative material on the lens and other ocular structures. This examination can reveal the characteristic flakes associated with the syndrome.

4. Assessment of Lens Status

  • The condition of the lens must be evaluated, as pseudoexfoliation can lead to lens instability and cataract formation, which may contribute to the development of capsular glaucoma.

5. Exclusion of Other Causes

  • It is important to rule out other types of glaucoma or secondary causes of elevated IOP. This may involve additional imaging or diagnostic tests to confirm that the glaucoma is indeed due to pseudoexfoliation.

Conclusion

The diagnosis of capsular glaucoma with pseudoexfoliation of the lens (ICD-10 H40.141) requires a comprehensive approach that includes clinical examination, patient history, and specific diagnostic tests. By carefully evaluating intraocular pressure, visual fields, optic nerve health, and the presence of pseudoexfoliative material, healthcare providers can accurately diagnose and manage this condition to prevent vision loss. Regular monitoring and appropriate treatment are essential for patients diagnosed with this type of glaucoma.

Treatment Guidelines

Capsular glaucoma with pseudoexfoliation of the lens, classified under ICD-10 code H40.141, is a specific type of glaucoma that occurs due to the accumulation of exfoliative material on the lens capsule, leading to increased intraocular pressure (IOP) and potential optic nerve damage. This condition primarily affects the right eye in this case. The management of this type of glaucoma typically involves a combination of medical, laser, and surgical treatments. Below is a detailed overview of the standard treatment approaches.

Medical Management

1. Topical Medications

The first line of treatment for capsular glaucoma often includes the use of topical medications aimed at lowering intraocular pressure. Common classes of medications include:

  • Prostaglandin Analogues: These are often the first choice due to their efficacy in reducing IOP. Examples include latanoprost and bimatoprost.
  • Beta-Blockers: Medications such as timolol can be used, especially in patients who may not tolerate prostaglandin analogues.
  • Alpha Agonists: Brimonidine is another option that can help reduce IOP.
  • Carbonic Anhydrase Inhibitors: Topical agents like dorzolamide can be effective, particularly in combination therapy.
  • Rho Kinase Inhibitors: Newer agents like netarsudil may also be considered for their dual mechanism of action.

2. Oral Medications

In some cases, oral carbonic anhydrase inhibitors (e.g., acetazolamide) may be prescribed to further reduce IOP, especially in acute situations or when topical medications are insufficient.

Laser Treatment

1. Laser Peripheral Iridotomy (LPI)

In cases where there is a risk of angle closure or if the patient has a narrow angle, LPI may be performed to create a new drainage pathway for aqueous humor, thereby reducing IOP.

2. Selective Laser Trabeculoplasty (SLT)

SLT can be utilized to enhance the outflow of aqueous humor through the trabecular meshwork, which can be particularly beneficial in patients with pseudoexfoliation glaucoma.

Surgical Interventions

1. Trabeculectomy

For patients who do not respond adequately to medical or laser treatments, surgical options such as trabeculectomy may be indicated. This procedure creates a new drainage pathway for aqueous humor, effectively lowering IOP.

2. Tube Shunt Surgery

In cases where trabeculectomy is not suitable or has failed, tube shunt surgery (e.g., Ahmed or Baerveldt implants) may be considered to provide an alternative route for aqueous drainage.

3. Minimally Invasive Glaucoma Surgery (MIGS)

MIGS techniques, such as the iStent or Hydrus Microstent, may be appropriate for select patients, particularly those with mild to moderate glaucoma.

Monitoring and Follow-Up

Regular follow-up appointments are crucial for monitoring IOP, assessing the optic nerve, and adjusting treatment as necessary. Patients should be educated about the importance of adherence to prescribed therapies and the potential side effects of medications.

Conclusion

The management of capsular glaucoma with pseudoexfoliation of the lens in the right eye involves a comprehensive approach tailored to the individual patient's needs. Initial treatment typically starts with topical medications, followed by laser treatments and, if necessary, surgical interventions. Continuous monitoring and patient education are essential components of effective glaucoma management to prevent vision loss and maintain quality of life.

Related Information

Description

  • Secondary form of glaucoma caused by pseudoexfoliation syndrome
  • Pseudoexfoliative material obstructs trabecular meshwork
  • Increased IOP due to obstruction in drainage system
  • Age-related condition associated with aging population
  • Blurred vision, halos around lights, and eye pain are symptoms
  • Comprehensive eye exam, IOP measurement, and gonioscopy for diagnosis
  • Medications, laser therapy, and surgical intervention for treatment

Clinical Information

  • Increased intraocular pressure causes optic nerve damage
  • Pseudoexfoliative material obstructs trabecular meshwork
  • Impaired aqueous humor outflow leads to glaucoma
  • Typically affects older adults over age 60
  • More prevalent in individuals of Scandinavian descent
  • Visual disturbances, halos around lights common symptoms
  • Increased IOP can cause headaches and eye pain
  • Optic nerve changes, such as cupping, are indicative
  • Pupil reaction may be irregular or non-reactive
  • Corneal changes, including deposits, can occur

Approximate Synonyms

  • Pseudoexfoliative Glaucoma
  • Exfoliative Glaucoma
  • Secondary Glaucoma

Diagnostic Criteria

Treatment Guidelines

  • Use prostaglandin analogues first
  • Try beta-blockers as alternatives
  • Alpha agonists can reduce IOP
  • Carbonic anhydrase inhibitors effective
  • Rho kinase inhibitors considered
  • Oral medications for acute cases
  • Laser peripheral iridotomy for angle closure
  • Selective laser trabeculoplasty beneficial
  • Trabeculectomy for unresponsive patients
  • Tube shunt surgery alternative option
  • Minimally invasive glaucoma surgery suitable

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