ICD-10: H44.122

Parasitic endophthalmitis, unspecified, left eye

Additional Information

Description

Parasitic endophthalmitis is a serious ocular condition characterized by inflammation of the interior of the eye due to parasitic infections. The ICD-10 code H44.122 specifically refers to this condition when it affects the left eye and is classified as "unspecified," indicating that the exact type of parasitic infection may not be clearly identified.

Clinical Description

Definition

Endophthalmitis is an inflammatory condition of the intraocular cavities, typically the vitreous and aqueous humor, which can be caused by various infectious agents, including bacteria, fungi, and parasites. Parasitic endophthalmitis, while less common than bacterial or fungal forms, can result from infections by parasites such as Toxoplasma gondii, Acanthamoeba, or other protozoa and helminths.

Symptoms

Patients with parasitic endophthalmitis may present with a range of symptoms, including:
- Decreased vision: Often the first noticeable symptom, which can vary from mild blurriness to complete loss of vision.
- Eye pain: Patients may experience significant discomfort or pain in the affected eye.
- Redness and swelling: The eye may appear red and inflamed, with possible swelling of the eyelids.
- Photophobia: Increased sensitivity to light can occur.
- Floaters: Patients may report seeing floaters or flashes of light due to inflammation in the vitreous body.

Diagnosis

Diagnosis of parasitic endophthalmitis typically involves:
- Clinical examination: An ophthalmologist will perform a thorough eye examination, including visual acuity tests and slit-lamp examination.
- Imaging studies: Optical coherence tomography (OCT) or ultrasound may be used to assess the extent of the infection and any associated retinal damage.
- Laboratory tests: Serological tests or PCR may be conducted to identify specific parasites.

Treatment

Management of parasitic endophthalmitis often requires a multidisciplinary approach, including:
- Antiparasitic medications: Depending on the identified parasite, treatments may include medications such as pyrimethamine and sulfadiazine for Toxoplasmosis or other specific antiparasitic agents.
- Surgical intervention: In severe cases, vitrectomy may be necessary to remove infected vitreous material and alleviate intraocular pressure.
- Supportive care: This may include corticosteroids to reduce inflammation and pain management.

Conclusion

ICD-10 code H44.122 captures the complexity of parasitic endophthalmitis in the left eye, emphasizing the need for accurate diagnosis and prompt treatment to prevent vision loss. Given the potential severity of this condition, timely referral to an ophthalmologist is crucial for effective management. Understanding the clinical presentation and treatment options is essential for healthcare providers dealing with ocular infections.

Clinical Information

Parasitic endophthalmitis, classified under ICD-10 code H44.122, refers to an intraocular infection caused by parasites, affecting the left eye. This condition can lead to significant visual impairment and requires prompt diagnosis and treatment. Below is a detailed overview of the clinical presentation, signs, symptoms, and patient characteristics associated with this condition.

Clinical Presentation

Overview

Parasitic endophthalmitis is characterized by inflammation of the interior of the eye, specifically the vitreous and/or the retina, due to parasitic infections. The condition can arise from various parasites, including protozoa, helminths, and other organisms, often linked to environmental exposure or underlying health conditions.

Common Causes

  • Toxoplasmosis: Often caused by the Toxoplasma gondii parasite, which can lead to retinochoroiditis.
  • Acanthamoeba: Typically associated with contact lens wear and can cause severe keratitis and subsequent endophthalmitis.
  • Other parasites: Such as those from the genus Strongyloides or filarial infections.

Signs and Symptoms

Symptoms

Patients with parasitic endophthalmitis may present with a variety of symptoms, including:
- Visual Disturbances: Blurred vision or sudden loss of vision in the affected eye.
- Eye Pain: Patients often report significant discomfort or pain in the left eye.
- Photophobia: Increased sensitivity to light.
- Redness: Conjunctival injection or redness in the eye.
- Floaters: The presence of floaters or spots in the visual field, indicating inflammation in the vitreous.

Signs

Upon examination, healthcare providers may observe:
- Fundoscopic Findings: Inflammatory changes in the retina, such as retinal hemorrhages, exudates, or necrotizing retinitis.
- Vitreous Opacity: Cloudiness in the vitreous body due to inflammatory cells.
- Anterior Chamber Reaction: Presence of cells and flare in the anterior chamber, indicating anterior uveitis.

Patient Characteristics

Demographics

  • Age: Parasitic endophthalmitis can occur in individuals of any age, but certain parasites may have age-related prevalence.
  • Geographic Location: Higher incidence in tropical and subtropical regions where specific parasites are endemic.
  • Health Status: Immunocompromised individuals (e.g., those with HIV/AIDS, diabetes, or on immunosuppressive therapy) are at increased risk for developing parasitic infections leading to endophthalmitis.

Risk Factors

  • Contact Lens Use: Particularly with Acanthamoeba infections.
  • Exposure to Contaminated Water: Swimming in freshwater lakes or using contaminated water for eye care.
  • Travel History: Recent travel to areas where parasitic infections are common may increase risk.

Conclusion

Parasitic endophthalmitis, particularly in the left eye as denoted by ICD-10 code H44.122, presents with a range of symptoms and signs that can significantly impact a patient's vision and quality of life. Early recognition and treatment are crucial to prevent irreversible damage. Understanding the clinical presentation, associated symptoms, and patient characteristics can aid healthcare providers in diagnosing and managing this serious ocular condition effectively.

Approximate Synonyms

ICD-10 code H44.122 refers specifically to "Parasitic endophthalmitis, unspecified, left eye." This condition is characterized by inflammation of the interior of the eye caused by parasitic infections. Understanding alternative names and related terms can help in better comprehending the condition and its implications in clinical settings.

Alternative Names for H44.122

  1. Parasitic Endophthalmitis: This is the primary term used to describe the condition, emphasizing the parasitic origin of the inflammation.
  2. Endophthalmitis due to Parasites: This phrase highlights the causative agents of the inflammation, which are parasites.
  3. Left Eye Parasitic Endophthalmitis: A more specific term that indicates the affected eye, which is the left eye in this case.
  1. Endophthalmitis: A broader term that refers to inflammation of the interior of the eye, which can be caused by various infectious agents, including bacteria, fungi, and parasites.
  2. Ocular Parasitic Infection: This term encompasses any parasitic infection affecting the eye, which may lead to conditions like endophthalmitis.
  3. Parasitic Uveitis: While not identical, this term refers to inflammation of the uvea (the middle layer of the eye) caused by parasites, which can sometimes overlap with endophthalmitis.
  4. Infectious Endophthalmitis: A general term that includes all types of endophthalmitis caused by infectious agents, including parasites, bacteria, and fungi.

Clinical Context

In clinical practice, understanding these terms is crucial for accurate diagnosis and treatment. Parasitic endophthalmitis can arise from various parasites, and its management may differ significantly from other forms of endophthalmitis. Identifying the specific type of parasitic infection is essential for effective treatment, which may include antiparasitic medications or surgical intervention, such as vitrectomy, depending on the severity of the condition[1][2].

In summary, while H44.122 specifically denotes parasitic endophthalmitis of the left eye, related terms and alternative names provide a broader context for understanding the condition and its implications in ophthalmology.

Diagnostic Criteria

The diagnosis of ICD-10 code H44.122, which refers to parasitic endophthalmitis, unspecified, left eye, involves a combination of clinical evaluation, patient history, and specific diagnostic criteria. Below is a detailed overview of the criteria typically used for diagnosing this condition.

Understanding Parasitic Endophthalmitis

Parasitic endophthalmitis is an intraocular infection caused by parasites, which can lead to severe inflammation of the eye's internal structures, including the vitreous and retina. This condition is often associated with significant visual impairment and requires prompt diagnosis and treatment.

Diagnostic Criteria

1. Clinical Symptoms

  • Visual Disturbances: Patients may report decreased vision or blurred vision in the affected eye.
  • Eye Pain: There may be significant discomfort or pain in the left eye.
  • Redness and Swelling: Signs of conjunctival injection or swelling of the eyelids may be present.
  • Photophobia: Increased sensitivity to light can occur.

2. Patient History

  • Exposure History: A thorough history should be taken to identify any potential exposure to parasites, such as travel to endemic areas, contact with contaminated water, or exposure to animals that may harbor parasites.
  • Systemic Symptoms: Inquiry about systemic symptoms such as fever, malaise, or other signs of infection can provide context for the ocular findings.

3. Ophthalmic Examination

  • Visual Acuity Testing: Assessing the level of vision in the left eye is crucial.
  • Slit-Lamp Examination: This examination can reveal signs of inflammation, such as keratic precipitates, anterior chamber reaction, or vitreous opacities.
  • Fundoscopic Examination: A detailed examination of the retina and vitreous is essential to identify any signs of endophthalmitis, such as retinal hemorrhages, exudates, or the presence of parasites.

4. Diagnostic Imaging

  • Ultrasound: B-scan ultrasonography may be utilized to evaluate the vitreous cavity for any abnormal masses or signs of inflammation that are not visible through direct examination.
  • Optical Coherence Tomography (OCT): This imaging technique can help assess the retinal layers and any associated pathology.

5. Laboratory Tests

  • Microbiological Studies: Samples from the vitreous or aqueous humor may be obtained for culture and sensitivity testing to identify the specific parasitic organism responsible for the infection.
  • Serological Tests: Blood tests may be performed to detect antibodies or antigens related to specific parasitic infections.

6. Differential Diagnosis

  • It is essential to rule out other causes of endophthalmitis, such as bacterial or fungal infections, which may present similarly. This may involve additional testing and clinical correlation.

Conclusion

The diagnosis of parasitic endophthalmitis, unspecified, left eye (ICD-10 H44.122) requires a comprehensive approach that includes clinical evaluation, patient history, and various diagnostic tests. Early recognition and treatment are critical to prevent vision loss and manage the infection effectively. If you suspect this condition, it is advisable to consult an ophthalmologist for a thorough assessment and appropriate management.

Treatment Guidelines

Parasitic endophthalmitis, classified under ICD-10 code H44.122, refers to an infection of the inner eye structures caused by parasites, specifically affecting the left eye. This condition can lead to severe visual impairment or loss if not treated promptly and effectively. Here’s a detailed overview of standard treatment approaches for this condition.

Understanding Parasitic Endophthalmitis

Parasitic endophthalmitis is a rare but serious condition that can arise from various parasitic infections, including those caused by organisms such as Toxoplasma gondii, Acanthamoeba, or other parasites. Symptoms may include blurred vision, eye pain, redness, and the presence of floaters. Diagnosis typically involves a thorough clinical examination, imaging studies, and possibly laboratory tests to identify the specific parasite involved.

Standard Treatment Approaches

1. Medical Management

  • Antimicrobial Therapy: The cornerstone of treatment for parasitic endophthalmitis is the use of appropriate antimicrobial agents. The choice of medication depends on the specific parasite identified:
  • Toxoplasmosis: Commonly treated with a combination of pyrimethamine and sulfadiazine, along with leucovorin to mitigate side effects.
  • Acanthamoeba: Treated with topical antiseptics such as chlorhexidine or polyhexamethylene biguanide (PHMB), often in conjunction with systemic medications like oral itraconazole or voriconazole.

  • Corticosteroids: In some cases, corticosteroids may be prescribed to reduce inflammation and control the immune response, but their use must be carefully monitored to avoid exacerbating the infection.

2. Surgical Intervention

  • Vitrectomy: In cases where medical management fails or if there is significant vitreous involvement, a vitrectomy may be necessary. This surgical procedure involves the removal of the vitreous gel and any infected tissue, allowing for better access to the infection and facilitating the delivery of medications directly to the affected area.

  • Intravitreal Injections: For certain types of parasitic infections, intravitreal injections of antifungal or antiparasitic agents may be indicated. This method allows for higher concentrations of the drug to be delivered directly to the site of infection.

3. Supportive Care

  • Monitoring and Follow-Up: Regular follow-up appointments are crucial to monitor the response to treatment and to detect any potential complications early. This may include visual acuity tests, intraocular pressure measurements, and imaging studies.

  • Patient Education: Educating patients about the nature of their condition, the importance of adherence to treatment, and potential side effects is essential for successful management.

Conclusion

The treatment of parasitic endophthalmitis, particularly for the left eye as indicated by ICD-10 code H44.122, requires a multifaceted approach that includes both medical and surgical interventions tailored to the specific parasite involved. Early diagnosis and prompt treatment are critical to preserving vision and preventing complications. Regular follow-up and patient education play vital roles in the overall management of this serious condition. If you suspect parasitic endophthalmitis, it is essential to consult an ophthalmologist for a comprehensive evaluation and treatment plan.

Related Information

Description

  • Inflammation of eye interior due to parasitic infection
  • Parasites such as Toxoplasma gondii, Acanthamoeba, or protozoa and helminths
  • Decreased vision is often the first noticeable symptom
  • Eye pain, redness, swelling, photophobia, and floaters may occur
  • Clinical examination, imaging studies, and laboratory tests are used for diagnosis
  • Antiparasitic medications, surgical intervention, and supportive care are treatment options

Clinical Information

  • Parasitic endophthalmitis affects left eye
  • Caused by protozoa, helminths, or other parasites
  • Toxoplasmosis often leads to retinochoroiditis
  • Acanthamoeba linked to contact lens wear and keratitis
  • Visual disturbances include blurred vision and loss of sight
  • Eye pain is significant in affected patients
  • Photophobia and redness also present symptoms
  • Floaters indicate inflammation in vitreous
  • Fundoscopic findings show retinal changes
  • Vitreous opacity caused by inflammatory cells
  • Anterior chamber reaction indicates anterior uveitis
  • Immunocompromised individuals at increased risk
  • Contact lens use increases risk of Acanthamoeba infection

Approximate Synonyms

  • Parasitic Endophthalmitis
  • Endophthalmitis due to Parasites
  • Left Eye Parasitic Endophthalmitis
  • Endophthalmitis
  • Ocular Parasitic Infection
  • Parasitic Uveitis
  • Infectious Endophthalmitis

Diagnostic Criteria

Treatment Guidelines

  • Antimicrobial therapy cornerstone of treatment
  • Pyrimethamine and sulfadiazine for Toxoplasmosis
  • Chlorhexidine or PHMB for Acanthamoeba
  • Vitrectomy in severe cases
  • Intravitreal injections for certain infections
  • Regular monitoring and follow-up
  • Patient education on treatment adherence

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