ICD-10: J82.82

Acute eosinophilic pneumonia

Additional Information

Approximate Synonyms

Acute eosinophilic pneumonia (AEP) is a specific condition characterized by the accumulation of eosinophils in the lungs, leading to respiratory symptoms. The ICD-10-CM code for this condition is J82.82. Understanding alternative names and related terms can help in clinical documentation, coding, and communication among healthcare professionals. Below are some alternative names and related terms associated with J82.82.

Alternative Names for Acute Eosinophilic Pneumonia

  1. Eosinophilic Pneumonia: This term is often used interchangeably with acute eosinophilic pneumonia, although it can also refer to chronic forms of the disease.

  2. Acute Eosinophilic Lung Disease: This broader term encompasses various eosinophilic lung conditions, including AEP.

  3. Eosinophilic Lung Infiltrates: This term describes the presence of eosinophils in lung tissue, which is a hallmark of AEP.

  4. Eosinophilic Pneumonitis: While pneumonitis generally refers to inflammation of lung tissue, it can be used to describe the inflammatory process seen in AEP.

  5. Drug-Induced Eosinophilic Pneumonia: This term is used when AEP is triggered by certain medications, highlighting a specific etiology.

  1. Pulmonary Eosinophilia: This is a broader category that includes various conditions characterized by eosinophil accumulation in the lungs, such as:
    - Chronic Eosinophilic Pneumonia (CEP): A long-term condition that can also present with eosinophilic infiltration.
    - Eosinophilic Asthma (J82.83): A related condition where eosinophils play a significant role in airway inflammation.

  2. Hypereosinophilia: This term refers to an elevated eosinophil count in the blood, which can be associated with various conditions, including AEP.

  3. Allergic Eosinophilic Pneumonia: This term may be used when AEP is associated with allergic reactions or conditions.

  4. Interstitial Lung Disease: While not specific to eosinophilic pneumonia, this term encompasses a range of lung diseases that can include eosinophilic infiltration.

  5. Eosinophilic Granulomatosis with Polyangiitis (EGPA): A systemic condition that can involve eosinophilic pneumonia as part of its clinical presentation.

Conclusion

Understanding the alternative names and related terms for acute eosinophilic pneumonia (ICD-10 code J82.82) is essential for accurate diagnosis, treatment, and coding in clinical practice. These terms not only facilitate better communication among healthcare providers but also enhance the understanding of the condition's various presentations and underlying mechanisms. If you have further questions or need more specific information, feel free to ask!

Description

Acute eosinophilic pneumonia (AEP) is a rare but significant respiratory condition characterized by the accumulation of eosinophils in the lung tissue, leading to inflammation and respiratory distress. The ICD-10 code J82.82 specifically designates this condition, allowing for accurate diagnosis and billing in clinical settings.

Clinical Description of Acute Eosinophilic Pneumonia

Pathophysiology

Acute eosinophilic pneumonia is primarily marked by an influx of eosinophils, a type of white blood cell involved in the body's immune response, particularly in allergic reactions and parasitic infections. In AEP, this accumulation occurs in the alveoli, the tiny air sacs in the lungs, leading to pulmonary inflammation and impaired gas exchange. The exact etiology of AEP can vary, but it is often associated with:

  • Infections: Certain viral infections can trigger eosinophilic responses.
  • Drug Reactions: Medications, particularly antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs), have been implicated.
  • Environmental Exposures: Inhalation of allergens or irritants can provoke eosinophilic infiltration.

Symptoms

Patients with acute eosinophilic pneumonia typically present with a range of respiratory symptoms, which may include:

  • Acute onset of dyspnea (shortness of breath)
  • Cough, which may be dry or productive
  • Fever and chills
  • Chest pain or discomfort
  • Fatigue and malaise

These symptoms can develop rapidly, often within days, and may be accompanied by systemic signs of inflammation.

Diagnosis

Diagnosis of AEP involves a combination of clinical evaluation, imaging studies, and laboratory tests. Key diagnostic steps include:

  • Chest X-ray or CT Scan: Imaging often reveals bilateral infiltrates, which are indicative of pulmonary involvement.
  • Bronchoscopy with Bronchoalveolar Lavage (BAL): This procedure allows for direct sampling of lung fluid, where eosinophils can be identified.
  • Eosinophil Count: A peripheral blood eosinophilia (elevated eosinophil count) may support the diagnosis, although it is not always present.

Treatment

Management of acute eosinophilic pneumonia typically involves:

  • Corticosteroids: Systemic corticosteroids are the mainstay of treatment, helping to reduce inflammation and eosinophil levels.
  • Supportive Care: Oxygen therapy and mechanical ventilation may be necessary in severe cases to support respiratory function.
  • Identifying and Avoiding Triggers: If a specific drug or environmental factor is identified, avoiding these triggers is crucial to prevent recurrence.

Conclusion

Acute eosinophilic pneumonia, classified under ICD-10 code J82.82, is a serious condition that requires prompt recognition and treatment. Understanding its clinical presentation, diagnostic criteria, and management strategies is essential for healthcare providers to ensure effective patient care. Early intervention can significantly improve outcomes, highlighting the importance of awareness and education regarding this rare pulmonary disorder.

Clinical Information

Acute eosinophilic pneumonia (AEP), classified under ICD-10 code J82.82, is a rare but significant pulmonary condition characterized by the accumulation of eosinophils in the lungs. This condition can present with a variety of clinical features, and understanding its signs, symptoms, and patient characteristics is crucial for timely diagnosis and management.

Clinical Presentation

Signs and Symptoms

The clinical presentation of acute eosinophilic pneumonia can vary widely among patients, but common signs and symptoms include:

  • Respiratory Symptoms: Patients often present with acute onset of respiratory distress, which may include:
  • Cough (often dry)
  • Shortness of breath (dyspnea)
  • Chest pain
  • Wheezing

  • Systemic Symptoms: In addition to respiratory issues, systemic symptoms may also be present:

  • Fever
  • Fatigue
  • Night sweats
  • Weight loss

  • Physical Examination Findings: Upon examination, healthcare providers may note:

  • Tachypnea (rapid breathing)
  • Hypoxemia (low blood oxygen levels)
  • Rales or crackles upon auscultation of the lungs

Radiological Findings

Chest imaging, particularly high-resolution computed tomography (HRCT), typically reveals:
- Bilateral ground-glass opacities
- Consolidation in the lung fields
- Possible pleural effusions

These imaging findings are critical for differentiating AEP from other pulmonary conditions, such as infections or other forms of pneumonia[1][4].

Patient Characteristics

Demographics

Acute eosinophilic pneumonia can affect individuals of various ages, but certain demographic trends have been observed:
- Age: It is most commonly seen in young adults, particularly those in their 20s to 40s, although cases can occur in older adults as well[2][3].
- Gender: There is a slight male predominance in reported cases, although both genders can be affected.

Risk Factors

Several risk factors have been associated with the development of AEP:
- Environmental Exposures: Exposure to certain allergens, drugs, or toxins can trigger eosinophilic responses. Common triggers include:
- Medications (e.g., non-steroidal anti-inflammatory drugs, antibiotics)
- Inhalation of organic dust or chemicals
- Underlying Conditions: Patients with pre-existing conditions such as asthma or other allergic disorders may be at higher risk for developing AEP[4][5].

Seasonality

Research indicates that there may be a seasonal component to the incidence of acute eosinophilic pneumonia, with cases more frequently reported in the spring and summer months, potentially linked to increased exposure to allergens during these times[2][3].

Conclusion

Acute eosinophilic pneumonia (ICD-10 code J82.82) is characterized by a distinct clinical presentation that includes respiratory and systemic symptoms, often accompanied by specific radiological findings. Understanding the demographics, risk factors, and potential seasonal patterns can aid healthcare providers in recognizing and diagnosing this condition promptly. Early identification and management are essential to improve patient outcomes and prevent complications associated with this rare pulmonary disorder.

For further information or specific case studies, consulting clinical guidelines or recent literature on eosinophilic pneumonias may provide additional insights into this condition[1][4][5].

Diagnostic Criteria

Acute eosinophilic pneumonia (AEP) is a rare but significant respiratory condition characterized by the accumulation of eosinophils in the lungs, leading to respiratory symptoms and impaired lung function. The diagnosis of AEP, which is classified under the ICD-10-CM code J82.82, involves a combination of clinical evaluation, imaging studies, and laboratory tests. Below are the key criteria used for diagnosing this condition.

Clinical Criteria

  1. Symptoms: Patients typically present with acute respiratory symptoms, which may include:
    - Cough
    - Dyspnea (shortness of breath)
    - Fever
    - Chest pain
    - Fatigue

  2. History: A thorough medical history is essential. Clinicians often look for:
    - Recent exposure to allergens or irritants (e.g., drugs, environmental factors)
    - History of asthma or other allergic conditions
    - Travel history that may suggest exposure to specific pathogens or environmental triggers

Radiological Criteria

  1. Imaging Studies: Chest X-rays or CT scans are crucial in the diagnostic process. Findings may include:
    - Bilateral infiltrates, often described as ground-glass opacities
    - Consolidation in the lung fields
    - Absence of other causes of pulmonary infiltrates, such as infections or malignancies

Laboratory Criteria

  1. Eosinophilia: A definitive diagnosis often requires laboratory confirmation of eosinophilia, which is characterized by:
    - Elevated eosinophil counts in peripheral blood (typically > 500 cells/µL)
    - Eosinophils in bronchoalveolar lavage fluid (BALF), which is often obtained during bronchoscopy

  2. Exclusion of Other Conditions: It is essential to rule out other potential causes of eosinophilia and pulmonary symptoms, such as:
    - Parasitic infections
    - Drug reactions
    - Other forms of pulmonary eosinophilia (e.g., Churg-Strauss syndrome, hypereosinophilic syndrome)

Additional Considerations

  • Response to Treatment: A positive response to corticosteroid therapy can support the diagnosis of AEP, as patients often show significant improvement in symptoms and radiological findings after starting treatment.
  • Histopathological Examination: In some cases, lung biopsy may be performed to confirm the presence of eosinophilic infiltration in lung tissue, although this is less common due to the invasive nature of the procedure.

Conclusion

The diagnosis of acute eosinophilic pneumonia (ICD-10 code J82.82) relies on a combination of clinical symptoms, imaging studies, laboratory findings, and the exclusion of other conditions. Given the complexity of the condition, a multidisciplinary approach involving pulmonologists, allergists, and pathologists may be beneficial for accurate diagnosis and management. Early recognition and treatment are crucial to improving patient outcomes and preventing complications associated with this condition.

Treatment Guidelines

Acute eosinophilic pneumonia (AEP), classified under ICD-10 code J82.82, is a rare but serious condition characterized by the accumulation of eosinophils in the lungs, leading to respiratory symptoms and impaired gas exchange. Understanding the standard treatment approaches for this condition is crucial for effective management and patient recovery.

Overview of Acute Eosinophilic Pneumonia

AEP is often associated with various triggers, including infections, drug reactions, and environmental exposures. Patients typically present with symptoms such as cough, dyspnea (shortness of breath), fever, and chest pain. Diagnosis is usually confirmed through imaging studies, such as chest X-rays or CT scans, and bronchoscopy with bronchoalveolar lavage (BAL) to analyze the eosinophil count in the lung fluid.

Standard Treatment Approaches

1. Corticosteroid Therapy

The cornerstone of treatment for acute eosinophilic pneumonia is the use of corticosteroids. These anti-inflammatory medications help reduce eosinophilic inflammation in the lungs. The typical regimen includes:

  • Initial High-Dose Corticosteroids: Patients may be started on high doses of systemic corticosteroids, such as prednisone, often at doses ranging from 1 to 2 mg/kg/day. This approach aims to quickly control inflammation and alleviate symptoms.
  • Tapering: Once clinical improvement is observed, the corticosteroid dose is gradually tapered over several weeks to minimize potential side effects associated with long-term steroid use[1].

2. Supportive Care

In addition to pharmacological treatment, supportive care is essential for managing symptoms and ensuring patient comfort. This may include:

  • Oxygen Therapy: For patients experiencing significant hypoxemia (low blood oxygen levels), supplemental oxygen may be necessary to maintain adequate oxygen saturation.
  • Mechanical Ventilation: In severe cases where respiratory failure occurs, mechanical ventilation may be required to support breathing until the condition improves[2].

3. Identifying and Addressing Underlying Causes

Since AEP can be triggered by various factors, identifying and addressing the underlying cause is crucial. This may involve:

  • Discontinuation of Offending Agents: If the condition is linked to a specific medication or environmental exposure, immediate cessation is necessary.
  • Management of Coexisting Conditions: Treating any concurrent infections or other respiratory conditions can also aid in recovery[3].

4. Monitoring and Follow-Up

Regular monitoring of the patient's respiratory status and eosinophil levels is important during treatment. Follow-up imaging may be necessary to assess the resolution of pulmonary infiltrates and ensure that the patient is responding to therapy.

Conclusion

The management of acute eosinophilic pneumonia primarily revolves around corticosteroid therapy, supportive care, and addressing any underlying causes. Early recognition and treatment are vital to prevent complications and promote recovery. As with any medical condition, individualized treatment plans should be developed based on the patient's specific circumstances and response to therapy. Continuous monitoring and follow-up care are essential to ensure optimal outcomes for patients diagnosed with this condition.

References

  1. Article - Billing and Coding: Respiratory Care (A57225).
  2. ICD-10 Coordination and Maintenance Committee Meeting.
  3. Clinical Policy: Pulmonary Function Testing.

Related Information

Approximate Synonyms

  • Eosinophilic Pneumonia
  • Acute Eosinophilic Lung Disease
  • Eosinophilic Lung Infiltrates
  • Eosinophilic Pneumonitis
  • Drug-Induced Eosinophilic Pneumonia
  • Pulmonary Eosinophilia
  • Chronic Eosinophilic Pneumonia
  • Eosinophilic Asthma
  • Hypereosinophilia
  • Allergic Eosinophilic Pneumonia
  • Interstitial Lung Disease
  • Eosinophilic Granulomatosis

Description

  • Eosinophils accumulate in lung tissue
  • Causes respiratory distress and inflammation
  • Primarily marked by eosinophil influx
  • Involves alveoli, tiny air sacs in lungs
  • Often associated with infections, drug reactions
  • Environmental exposures can provoke eosinophilic infiltration
  • Symptoms include acute onset of dyspnea
  • Cough, fever, chest pain and fatigue
  • Diagnosis involves imaging studies and lab tests
  • Chest X-ray or CT scan reveals bilateral infiltrates
  • Bronchoscopy with BAL allows for lung fluid sampling
  • Eosinophil count supports diagnosis but not always present
  • Management includes corticosteroids and supportive care
  • Identifying and avoiding triggers is crucial

Clinical Information

  • Respiratory symptoms: cough, shortness of breath
  • Chest pain, wheezing, fever, fatigue
  • Tachypnea, hypoxemia, rales or crackles on auscultation
  • Bilateral ground-glass opacities on chest imaging
  • Consolidation in lung fields, possible pleural effusions
  • Young adults most commonly affected, slight male predominance

Diagnostic Criteria

  • Symptoms: Cough, dyspnea, fever, chest pain
  • Recent exposure to allergens or irritants
  • History of asthma or other allergic conditions
  • Travel history that may suggest environmental triggers
  • Bilateral infiltrates on imaging studies
  • Elevated eosinophil counts in peripheral blood
  • Eosinophils in bronchoalveolar lavage fluid (BALF)
  • Absence of other causes of pulmonary infiltrates
  • Positive response to corticosteroid therapy

Treatment Guidelines

  • Corticosteroids as first-line treatment
  • High-dose corticosteroids initially
  • Gradual tapering of corticosteroid dose
  • Oxygen therapy for hypoxemia
  • Mechanical ventilation in severe cases
  • Discontinuation of offending agents
  • Management of coexisting conditions

Related Diseases

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