ICD-10: K25.1

Acute gastric ulcer with perforation

Additional Information

Clinical Information

Acute gastric ulcers with perforation, classified under ICD-10 code K25.1, represent a serious medical condition that requires immediate attention. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for timely diagnosis and management.

Clinical Presentation

Acute gastric ulcers are characterized by the sudden onset of ulceration in the gastric mucosa, which can lead to perforation—an emergency situation where the ulcer creates a hole in the stomach wall. This condition often presents with severe abdominal pain and can lead to peritonitis, a serious inflammation of the abdominal cavity.

Signs and Symptoms

  1. Abdominal Pain:
    - Patients typically experience sudden, severe abdominal pain, often described as sharp or stabbing. This pain may be localized to the epigastric region but can also radiate to other areas of the abdomen[1].

  2. Nausea and Vomiting:
    - Nausea is common, and patients may vomit, which can sometimes include blood (hematemesis) if there is significant bleeding[1][2].

  3. Signs of Peritonitis:
    - Physical examination may reveal signs of peritonitis, such as abdominal rigidity, rebound tenderness, and guarding, indicating irritation of the peritoneum due to leakage of gastric contents[2].

  4. Changes in Vital Signs:
    - Patients may exhibit tachycardia (increased heart rate) and hypotension (low blood pressure) due to blood loss and shock, which are critical indicators of the severity of the condition[3].

  5. Melena:
    - The presence of black, tarry stools (melena) can indicate upper gastrointestinal bleeding, which may accompany perforation[1].

Patient Characteristics

  1. Demographics:
    - Acute gastric ulcers with perforation can occur in individuals of any age, but they are more prevalent in older adults, particularly those over 60 years of age[4].

  2. Risk Factors:
    - Common risk factors include a history of peptic ulcer disease, chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs), smoking, excessive alcohol consumption, and stress[4][5].

  3. Comorbid Conditions:
    - Patients may have underlying conditions such as chronic gastritis, Helicobacter pylori infection, or a history of gastrointestinal surgeries, which can predispose them to ulcer formation and complications[5].

  4. Gender:
    - There is a slight male predominance in the incidence of gastric ulcers, although the gap has been narrowing in recent years due to changing lifestyle factors[4].

Conclusion

Acute gastric ulcers with perforation (ICD-10 code K25.1) present a critical clinical scenario characterized by severe abdominal pain, nausea, and signs of peritonitis. Recognizing the symptoms and understanding the patient characteristics, including demographics and risk factors, is essential for healthcare providers to ensure prompt diagnosis and intervention. Early recognition and management can significantly improve patient outcomes and reduce the risk of complications associated with this serious condition.

Approximate Synonyms

ICD-10 code K25.1 refers specifically to "Acute gastric ulcer with perforation." This diagnosis is part of a broader classification of gastric ulcers and related gastrointestinal conditions. Below are alternative names and related terms associated with this code:

Alternative Names

  1. Acute Gastric Ulcer: This term emphasizes the acute nature of the ulcer, which is characterized by sudden onset and severe symptoms.
  2. Perforated Gastric Ulcer: This name highlights the critical complication of perforation, where the ulcer creates a hole in the stomach wall, leading to serious health risks.
  3. Acute Peptic Ulcer with Perforation: This term can be used interchangeably, as peptic ulcers include both gastric and duodenal ulcers.
  1. Gastric Ulcer (K25): The broader category under which K25.1 falls, encompassing all types of gastric ulcers.
  2. Peptic Ulcer Disease: A general term that includes both gastric and duodenal ulcers, often used in clinical settings.
  3. Gastrointestinal Perforation: A more general term that refers to any perforation in the gastrointestinal tract, which can include gastric ulcers.
  4. Acute Abdomen: A clinical term that may be used when a patient presents with severe abdominal pain due to complications like perforation.
  5. Ulcerative Gastritis: While not identical, this term refers to inflammation of the stomach lining that can lead to ulcer formation.

Clinical Context

Understanding these alternative names and related terms is crucial for healthcare professionals when diagnosing and coding conditions accurately. The specificity of K25.1 indicates not only the presence of an ulcer but also the critical nature of its perforation, which requires immediate medical attention.

In summary, K25.1 is associated with various terms that reflect its clinical significance and the urgency of treatment required for patients experiencing this condition.

Diagnostic Criteria

The ICD-10 code K25.1 refers specifically to an acute gastric ulcer with perforation. Diagnosing this condition involves a combination of clinical evaluation, patient history, and diagnostic imaging or procedures. Below are the key criteria and considerations used in the diagnosis of K25.1.

Clinical Presentation

  1. Symptoms: Patients typically present with severe abdominal pain, which may be sudden and intense. Other symptoms can include:
    - Nausea and vomiting
    - Abdominal distension
    - Signs of gastrointestinal bleeding, such as melena (black, tarry stools) or hematemesis (vomiting blood) [3][4].

  2. Physical Examination: A thorough physical examination may reveal:
    - Tenderness in the abdomen, particularly in the upper quadrants
    - Signs of peritonitis, such as rigidity or rebound tenderness, indicating possible perforation [8].

Diagnostic Imaging

  1. Radiological Studies: Imaging techniques are crucial for confirming the diagnosis:
    - X-rays: An upright abdominal X-ray may show free air under the diaphragm, indicating perforation.
    - CT Scan: A computed tomography (CT) scan of the abdomen is often the preferred method, as it provides detailed images and can confirm the presence of an ulcer and any associated complications, such as perforation or abscess formation [6][9].

  2. Endoscopy: In some cases, an upper gastrointestinal endoscopy may be performed to visualize the ulcer directly and assess its severity. This procedure can also help in obtaining biopsy samples if malignancy is suspected [5][7].

Laboratory Tests

  1. Blood Tests: Laboratory tests may include:
    - Complete blood count (CBC) to check for anemia, which may indicate bleeding.
    - Electrolyte levels and renal function tests to assess the patient's overall health and any complications from vomiting or dehydration [4][10].

  2. Stool Tests: Testing for occult blood in the stool can help identify gastrointestinal bleeding, which is a common complication of gastric ulcers [3].

Differential Diagnosis

It is essential to differentiate acute gastric ulcers with perforation from other conditions that may present similarly, such as:
- Perforated appendicitis
- Pancreatitis
- Cholecystitis
- Other gastrointestinal perforations [8][9].

Conclusion

The diagnosis of an acute gastric ulcer with perforation (ICD-10 code K25.1) is a multifaceted process that relies on a combination of clinical symptoms, physical examination findings, imaging studies, and laboratory tests. Prompt diagnosis and treatment are critical, as perforation can lead to serious complications, including peritonitis and sepsis. If you suspect a patient may have this condition, immediate medical evaluation is essential to ensure timely intervention.

Treatment Guidelines

Acute gastric ulcer with perforation, classified under ICD-10 code K25.1, is a serious medical condition that requires immediate attention and intervention. This condition occurs when an ulcer in the stomach wall creates a hole, leading to the leakage of gastric contents into the abdominal cavity, which can result in peritonitis and other complications. Here’s a detailed overview of the standard treatment approaches for this condition.

Initial Assessment and Diagnosis

Before treatment can begin, a thorough assessment is essential. This typically includes:

  • Clinical Evaluation: Patients often present with severe abdominal pain, signs of peritonitis (such as rigidity and rebound tenderness), and symptoms of shock (e.g., hypotension, tachycardia) due to blood loss.
  • Imaging Studies: An abdominal X-ray or CT scan may be performed to confirm the presence of free air under the diaphragm, indicating perforation[1][2].

Emergency Management

Once perforation is confirmed, immediate management is critical:

  1. Stabilization:
    - Fluid Resuscitation: Intravenous fluids are administered to manage shock and restore hemodynamic stability.
    - Blood Transfusion: If there is significant blood loss, transfusions may be necessary to stabilize the patient[3].

  2. Surgical Intervention:
    - Emergency Surgery: The definitive treatment for a perforated gastric ulcer is surgical intervention. This may involve:

    • Suturing the Perforation: A common approach is to close the perforation with sutures.
    • Omental Patch: In some cases, an omental patch may be used to cover the perforation.
    • Partial Gastrectomy: If the ulcer is extensive or recurrent, a partial gastrectomy may be performed to remove the affected portion of the stomach[4][5].

Postoperative Care

Following surgery, patients require careful monitoring and supportive care:

  • Pain Management: Adequate analgesia is crucial for recovery.
  • Nutritional Support: Initially, patients may require intravenous nutrition (TPN) until they can tolerate oral intake.
  • Antibiotics: Prophylactic antibiotics are often administered to prevent infection, especially in cases of peritonitis[6].

Long-term Management

After recovery from the acute episode, long-term management strategies are essential to prevent recurrence:

  1. Medications:
    - Proton Pump Inhibitors (PPIs): These are commonly prescribed to reduce gastric acid secretion and promote healing of the gastric mucosa.
    - Antibiotics for H. pylori: If Helicobacter pylori infection is present, eradication therapy is necessary to prevent future ulcers[7].

  2. Lifestyle Modifications:
    - Dietary Changes: Patients are advised to avoid irritants such as NSAIDs, alcohol, and smoking, which can exacerbate ulcer formation.
    - Regular Follow-up: Continuous monitoring and follow-up with a gastroenterologist are recommended to manage any underlying conditions and monitor for recurrence[8].

Conclusion

Acute gastric ulcer with perforation is a medical emergency that necessitates prompt diagnosis and intervention. The standard treatment involves stabilization of the patient, surgical repair of the perforation, and comprehensive postoperative care. Long-term management focuses on preventing recurrence through medication and lifestyle changes. Early recognition and appropriate treatment are crucial for improving patient outcomes and reducing complications associated with this serious condition.

Description

Acute gastric ulcers are a significant medical condition characterized by the erosion of the stomach lining, which can lead to serious complications, including perforation. The ICD-10 code K25.1 specifically refers to an acute gastric ulcer that has resulted in perforation, indicating a severe and urgent medical situation.

Clinical Description of Acute Gastric Ulcer with Perforation (K25.1)

Definition

An acute gastric ulcer is a sudden onset of a sore or lesion in the stomach lining. When this ulcer penetrates through the entire wall of the stomach, it is termed a perforated gastric ulcer. This condition can lead to the leakage of gastric contents into the abdominal cavity, resulting in peritonitis, a life-threatening infection.

Symptoms

Patients with a perforated gastric ulcer may present with a variety of symptoms, including:
- Severe abdominal pain: Often described as sharp or stabbing, typically localized in the upper abdomen.
- Nausea and vomiting: Patients may experience significant discomfort and may vomit, sometimes with blood.
- Signs of shock: Due to internal bleeding, patients may exhibit symptoms such as rapid heartbeat, low blood pressure, and confusion.
- Abdominal rigidity: The abdomen may feel hard or tense upon examination, indicating irritation of the peritoneum.

Causes

The development of acute gastric ulcers can be attributed to several factors, including:
- Helicobacter pylori infection: A common bacterial infection that can lead to inflammation and ulceration of the stomach lining.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): Prolonged use of NSAIDs can damage the gastric mucosa, increasing the risk of ulcer formation.
- Excessive alcohol consumption: Alcohol can irritate and erode the stomach lining.
- Stress: Severe physical stress, such as from surgery or trauma, can also contribute to ulcer formation.

Diagnosis

Diagnosis of a perforated gastric ulcer typically involves:
- Clinical evaluation: A thorough history and physical examination to assess symptoms and signs of perforation.
- Imaging studies: X-rays or CT scans may be performed to confirm the presence of free air in the abdominal cavity, indicative of perforation.
- Endoscopy: In some cases, an upper gastrointestinal endoscopy may be used to visualize the ulcer directly.

Treatment

The management of an acute gastric ulcer with perforation is often surgical and may include:
- Emergency surgery: To repair the perforation and clean the abdominal cavity.
- Antibiotics: To treat or prevent infection.
- Acid-reducing medications: Such as proton pump inhibitors (PPIs) to promote healing of the ulcer.
- Lifestyle modifications: Post-recovery, patients are advised to avoid NSAIDs, limit alcohol intake, and manage stress effectively.

Prognosis

The prognosis for patients with a perforated gastric ulcer largely depends on the timeliness of treatment. Early intervention can lead to favorable outcomes, while delayed treatment may result in severe complications, including sepsis or death.

In summary, the ICD-10 code K25.1 denotes a critical condition requiring immediate medical attention. Understanding the clinical aspects of acute gastric ulcers with perforation is essential for healthcare providers to ensure prompt diagnosis and effective treatment, ultimately improving patient outcomes.

Related Information

Clinical Information

  • Sudden onset of severe abdominal pain
  • Abdominal rigidity and rebound tenderness
  • Changes in vital signs (tachycardia, hypotension)
  • Nausea and vomiting with possible hematemesis
  • Melena indicating upper GI bleeding
  • Common risk factors include NSAID use and smoking
  • Underlying conditions like H. pylori infection common

Approximate Synonyms

  • Acute Gastric Ulcer
  • Perforated Gastric Ulcer
  • Acute Peptic Ulcer with Perforation
  • Gastric Ulcer (K25)
  • Peptic Ulcer Disease
  • Gastrointestinal Perforation
  • Acute Abdomen
  • Ulcerative Gastritis

Diagnostic Criteria

  • Severe abdominal pain
  • Nausea and vomiting
  • Abdominal distension
  • Gastrointestinal bleeding
  • Tenderness in upper quadrants
  • Peritonitis signs
  • Free air under diaphragm
  • Ulcer visualization on endoscopy
  • Biopsy samples for malignancy
  • Anemia from CBC
  • Electrolyte imbalance
  • Stool occult blood

Treatment Guidelines

  • Fluid Resuscitation
  • Blood Transfusion
  • Stabilization
  • Surgical Intervention
  • Omental Patch
  • Partial Gastrectomy
  • Pain Management
  • Nutritional Support
  • Antibiotics
  • Proton Pump Inhibitors (PPIs)
  • Antibiotics for H. pylori
  • Dietary Changes
  • Regular Follow-up

Description

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