ICD-10: K65.3

Choleperitonitis

Clinical Information

Inclusion Terms

  • Peritonitis due to bile

Additional Information

Clinical Information

Choleperitonitis, classified under ICD-10 code K65.3, is a specific type of peritonitis characterized by the presence of bile in the peritoneal cavity, often resulting from biliary tract disease or complications such as perforation of the gallbladder. Understanding its clinical presentation, signs, symptoms, and patient characteristics is crucial for timely diagnosis and management.

Clinical Presentation

Choleperitonitis typically presents with acute abdominal symptoms that may escalate rapidly. The condition is often secondary to underlying biliary pathology, such as cholecystitis or choledocholithiasis, leading to bile leakage into the peritoneal cavity.

Signs and Symptoms

  1. Abdominal Pain:
    - Patients usually report severe, diffuse abdominal pain that may be localized initially but can become generalized as the condition progresses. The pain is often described as sharp or stabbing and may worsen with movement or palpation.

  2. Abdominal Tenderness:
    - On physical examination, there is often significant tenderness upon palpation of the abdomen, particularly in the right upper quadrant, where the gallbladder is located. Rebound tenderness may also be present, indicating peritoneal irritation.

  3. Fever and Chills:
    - Patients frequently exhibit fever, which can be high-grade, accompanied by chills, reflecting an inflammatory response to infection.

  4. Nausea and Vomiting:
    - Gastrointestinal symptoms such as nausea and vomiting are common, often due to the irritation of the peritoneum and the body's response to pain.

  5. Altered Bowel Habits:
    - Patients may experience changes in bowel habits, including diarrhea or constipation, depending on the severity of the condition and associated complications.

  6. Signs of Shock:
    - In severe cases, patients may present with signs of septic shock, including hypotension, tachycardia, and altered mental status, necessitating immediate medical intervention.

Patient Characteristics

Choleperitonitis can occur in various patient populations, but certain characteristics may predispose individuals to this condition:

  1. Age:
    - It is more commonly seen in middle-aged and older adults, particularly those over 50 years, due to the increased prevalence of gallbladder disease in this demographic.

  2. Gender:
    - There is a slight female predominance, as women are more likely to develop gallstones, which are a common cause of choleperitonitis.

  3. Underlying Conditions:
    - Patients with a history of gallbladder disease, such as cholecystitis or choledocholithiasis, are at higher risk. Other contributing factors may include obesity, diabetes, and liver disease.

  4. Recent Surgical History:
    - Individuals who have undergone recent abdominal surgery, particularly involving the biliary system, may be at increased risk for developing choleperitonitis due to potential complications such as bile leaks.

  5. Immunocompromised State:
    - Patients with weakened immune systems, whether due to chronic illness, medications, or other factors, may be more susceptible to infections leading to choleperitonitis.

Conclusion

Choleperitonitis is a serious condition that requires prompt recognition and treatment. Its clinical presentation is characterized by severe abdominal pain, fever, and signs of peritoneal irritation, often in patients with underlying biliary disease. Understanding the signs, symptoms, and patient characteristics associated with this condition is essential for healthcare providers to ensure timely intervention and improve patient outcomes. Early diagnosis and management can significantly reduce morbidity and mortality associated with this potentially life-threatening condition.

Treatment Guidelines

Choleperitonitis, classified under ICD-10 code K65.3, refers to the inflammation of the peritoneum due to bile leakage, often resulting from conditions such as gallbladder disease or bile duct obstruction. This condition can lead to serious complications if not treated promptly. Here, we will explore the standard treatment approaches for choleperitonitis, including diagnostic methods, medical management, and surgical interventions.

Diagnosis of Choleperitonitis

Before treatment can begin, accurate diagnosis is crucial. The following methods are typically employed:

  • Clinical Evaluation: Patients often present with abdominal pain, fever, and signs of peritoneal irritation. A thorough history and physical examination are essential.
  • Imaging Studies: Ultrasound and computed tomography (CT) scans are commonly used to identify the presence of free fluid in the abdomen, gallstones, or other abnormalities that may indicate bile leakage[1].
  • Laboratory Tests: Blood tests may reveal elevated white blood cell counts and liver function tests that indicate biliary obstruction or liver dysfunction[1].

Medical Management

Initial management of choleperitonitis focuses on stabilizing the patient and addressing the underlying cause:

  • Fluid Resuscitation: Intravenous fluids are administered to maintain hydration and support blood pressure, especially if the patient is in shock[1].
  • Antibiotic Therapy: Broad-spectrum antibiotics are initiated to combat potential infections. Common regimens may include piperacillin-tazobactam or a combination of a third-generation cephalosporin with metronidazole[1][2].
  • Pain Management: Analgesics are provided to manage abdominal pain, which can be severe in these cases[1].

Surgical Interventions

In many cases, surgical intervention is necessary to address the source of bile leakage and to manage the peritoneal contamination:

  • Exploratory Laparotomy: This procedure allows for direct visualization of the abdominal cavity, identification of the source of bile leakage, and necessary repairs. It is often performed in cases of severe choleperitonitis[2].
  • Cholecystectomy: If the gallbladder is the source of the problem, a cholecystectomy (removal of the gallbladder) may be performed. This can be done laparoscopically or via open surgery, depending on the severity of the condition and the patient's overall health[2].
  • Drainage Procedures: If there is significant fluid accumulation, peritoneal drainage may be necessary to remove infected or bile-contaminated fluid[1].

Postoperative Care

Post-surgery, patients require careful monitoring and supportive care:

  • Monitoring for Complications: Patients are observed for signs of infection, bleeding, or other complications that may arise postoperatively[2].
  • Nutritional Support: Depending on the extent of surgery and recovery, nutritional support may be necessary, often starting with intravenous nutrition before transitioning to oral intake[1].

Conclusion

Choleperitonitis is a serious condition that requires prompt diagnosis and treatment to prevent complications. The standard treatment approach involves a combination of medical management, including fluid resuscitation and antibiotics, followed by surgical intervention to address the underlying cause. Postoperative care is crucial for recovery and to monitor for potential complications. Early intervention can significantly improve outcomes for patients suffering from this condition.

For further information or specific case management, consulting with a healthcare professional specializing in gastroenterology or surgery is recommended.

Description

Choleperitonitis, classified under ICD-10-CM code K65.3, is a specific type of peritonitis characterized by the presence of bile in the peritoneal cavity, typically resulting from a rupture of the biliary system or complications from gallbladder disease. This condition can lead to significant morbidity and requires prompt medical intervention.

Clinical Description

Definition

Choleperitonitis refers to the inflammation of the peritoneum, the membrane lining the abdominal cavity, due to the leakage of bile. This leakage can occur from various sources, including:

  • Ruptured gallbladder: Often due to acute cholecystitis.
  • Biliary tract obstruction: Resulting in increased pressure and subsequent rupture.
  • Trauma: Direct injury to the biliary system.

Symptoms

Patients with choleperitonitis may present with a range of symptoms, including:

  • Abdominal pain: Typically severe and diffuse, often worsening with movement.
  • Fever: Indicative of infection or inflammation.
  • Nausea and vomiting: Commonly associated with abdominal distress.
  • Signs of peritoneal irritation: Such as rebound tenderness or guarding during physical examination.

Diagnosis

Diagnosis of choleperitonitis involves a combination of clinical evaluation and imaging studies. Key diagnostic steps include:

  • Physical examination: Assessing for abdominal tenderness and rigidity.
  • Imaging: CT scans or ultrasounds can help identify free fluid in the abdominal cavity and potential sources of bile leakage.
  • Laboratory tests: Blood tests may reveal leukocytosis and elevated liver enzymes, indicating an inflammatory process.

Treatment

The management of choleperitonitis typically requires surgical intervention, especially if there is a significant bile leak or associated complications. Treatment options include:

  • Surgical exploration: To identify and repair the source of bile leakage.
  • Drainage: Placement of drains to remove bile and infected fluid from the peritoneal cavity.
  • Antibiotic therapy: To manage infection and prevent sepsis.

Prognosis

The prognosis for patients with choleperitonitis largely depends on the underlying cause, the timeliness of diagnosis, and the effectiveness of treatment. Early intervention is crucial to reduce the risk of complications such as sepsis or multi-organ failure.

Conclusion

Choleperitonitis, represented by ICD-10 code K65.3, is a serious condition that necessitates immediate medical attention. Understanding its clinical presentation, diagnostic approach, and treatment options is essential for healthcare providers to ensure optimal patient outcomes. Prompt recognition and management can significantly improve the prognosis for affected individuals.

Approximate Synonyms

Choleperitonitis, classified under ICD-10 code K65.3, refers to the inflammation of the peritoneum due to bile leakage, often resulting from conditions such as gallbladder disease or bile duct obstruction. Understanding alternative names and related terms can enhance clarity in medical documentation and communication. Here’s a detailed overview:

Alternative Names for Choleperitonitis

  1. Biliary Peritonitis: This term emphasizes the biliary origin of the peritoneal inflammation, highlighting the involvement of bile in the condition.
  2. Bile Peritonitis: Similar to biliary peritonitis, this name focuses on the presence of bile in the peritoneal cavity as a causative factor.
  3. Peritoneal Bile Leakage: This term describes the mechanism of the condition, where bile leaks into the peritoneal cavity, leading to inflammation.
  4. Cholecystitis-Associated Peritonitis: This name links choleperitonitis to cholecystitis, an inflammation of the gallbladder, which can lead to bile leakage and subsequent peritoneal inflammation.
  1. Peritonitis (ICD-10 Code K65): This broader term encompasses all types of peritoneal inflammation, including those caused by infectious agents or other irritants, not limited to bile.
  2. Acute Abdomen: This term is often used in clinical settings to describe a sudden onset of abdominal pain, which may include choleperitonitis as a differential diagnosis.
  3. Biliary Tract Infection: While not synonymous, infections in the biliary tract can lead to conditions like choleperitonitis, making this term relevant in discussions about the disease.
  4. Gallbladder Disease: This term encompasses various conditions affecting the gallbladder, which can lead to complications such as choleperitonitis.

Clinical Context

Choleperitonitis is a serious condition that requires prompt medical attention. It is often associated with complications from gallstones, trauma, or surgical procedures involving the biliary system. Understanding the alternative names and related terms can aid healthcare professionals in accurately diagnosing and treating patients, as well as in coding for insurance and statistical purposes.

In summary, recognizing the various names and related terms for choleperitonitis enhances communication among healthcare providers and improves patient care by ensuring clarity in diagnosis and treatment strategies.

Diagnostic Criteria

Choleperitonitis, classified under ICD-10 code K65.3, refers to the inflammation of the peritoneum due to the presence of bile. This condition is often a complication of biliary tract diseases, such as cholecystitis or bile duct obstruction. The diagnosis of choleperitonitis involves several clinical criteria and diagnostic procedures. Below is a detailed overview of the criteria used for diagnosis.

Clinical Criteria for Diagnosis

1. Patient History

  • Symptoms: Patients typically present with abdominal pain, which may be diffuse or localized, often accompanied by fever, nausea, and vomiting. A history of gallbladder disease or previous abdominal surgeries may also be relevant.
  • Risk Factors: Consideration of risk factors such as age, gender, and underlying conditions (e.g., liver disease, diabetes) is essential.

2. Physical Examination

  • Abdominal Tenderness: The examination often reveals tenderness, particularly in the right upper quadrant, which may indicate irritation of the peritoneum.
  • Rebound Tenderness: This may be present, suggesting peritoneal irritation.
  • Signs of Peritonitis: Other signs may include rigidity of the abdominal wall and decreased bowel sounds.

3. Laboratory Tests

  • Complete Blood Count (CBC): An elevated white blood cell count (leukocytosis) may indicate infection or inflammation.
  • Liver Function Tests: Abnormal liver function tests may suggest biliary obstruction or liver involvement.
  • Bilirubin Levels: Elevated bilirubin levels can indicate cholestasis or bile duct obstruction.

4. Imaging Studies

  • Ultrasound: This is often the first imaging modality used to assess for gallstones, bile duct dilation, or fluid collections in the abdomen.
  • CT Scan of the Abdomen: A CT scan can provide detailed images of the abdominal organs and help identify the presence of free fluid, abscesses, or other complications associated with choleperitonitis. It is particularly useful in confirming the diagnosis and assessing the extent of the disease[4][9].

5. Diagnostic Paracentesis

  • In some cases, a paracentesis may be performed to analyze peritoneal fluid. The presence of bile in the fluid can confirm the diagnosis of choleperitonitis.

Differential Diagnosis

It is crucial to differentiate choleperitonitis from other causes of peritonitis, such as:
- Perforated Visceral Organ: Conditions like perforated appendicitis or diverticulitis can present similarly.
- Secondary Peritonitis: This can arise from other intra-abdominal infections or conditions.

Conclusion

The diagnosis of choleperitonitis (ICD-10 code K65.3) relies on a combination of clinical evaluation, laboratory tests, and imaging studies. Early recognition and diagnosis are vital for effective management, as choleperitonitis can lead to severe complications if not treated promptly. If you suspect choleperitonitis, it is essential to consult a healthcare professional for a thorough evaluation and appropriate intervention.

Related Information

Clinical Information

  • Severe abdominal pain
  • Abdominal tenderness and rebound
  • Fever and chills
  • Nausea and vomiting
  • Altered bowel habits
  • Signs of septic shock
  • Increased risk in middle-aged adults
  • Female predominance due to gallstones
  • Underlying biliary disease
  • Recent abdominal surgery complications
  • Immunocompromised state increases susceptibility

Treatment Guidelines

  • Clinical Evaluation is essential for diagnosis
  • Imaging Studies such as Ultrasound and CT scans are used
  • Laboratory Tests including Blood tests for liver function
  • Fluid Resuscitation to maintain hydration and blood pressure
  • Antibiotic Therapy with piperacillin-tazobactam or cephalosporin
  • Pain Management with Analgesics for severe abdominal pain
  • Exploratory Laparotomy for direct visualization of bile leakage
  • Cholecystectomy to remove gallbladder if necessary
  • Drainage Procedures to remove infected fluid
  • Monitoring for postoperative complications and bleeding

Description

  • Inflammation of peritoneum due to bile leakage
  • Leakage from ruptured gallbladder or biliary tract
  • Severe abdominal pain and diffuse tenderness
  • Fever, nausea, and vomiting due to infection
  • Physical examination reveals rebound tenderness and guarding
  • Imaging studies show free fluid in the abdominal cavity
  • Laboratory tests reveal leukocytosis and elevated liver enzymes
  • Surgical intervention required for significant bile leak or complications

Approximate Synonyms

  • Biliary Peritonitis
  • Bile Peritonitis
  • Peritoneal Bile Leakage
  • Cholecystitis-Associated Peritonitis

Diagnostic Criteria

  • Abdominal pain often accompanied by fever
  • Nausea and vomiting may be present
  • Right upper quadrant tenderness
  • Rebound tenderness indicating peritoneal irritation
  • Signs of peritonitis such as rigidity and decreased bowel sounds
  • Elevated white blood cell count (leukocytosis)
  • Abnormal liver function tests indicating biliary obstruction
  • Elevated bilirubin levels suggesting cholestasis or bile duct obstruction
  • Ultrasound for gallstones, bile duct dilation, or fluid collections
  • CT scan of the abdomen to identify complications and extent

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