ICD-10: M10.242

Drug-induced gout, left hand

Additional Information

Description

ICD-10 code M10.242 refers specifically to "Drug-induced gout, left hand." This classification falls under the broader category of gout, which is a type of inflammatory arthritis characterized by sudden and severe pain, redness, and swelling in the joints, often affecting the big toe but can also involve other joints, including those in the hands.

Clinical Description of Drug-Induced Gout

Overview of Gout

Gout is caused by the accumulation of uric acid crystals in the joints, leading to inflammation and intense pain. It can be triggered by various factors, including dietary choices, obesity, and certain medications. Drug-induced gout occurs when specific medications elevate uric acid levels or interfere with its excretion, resulting in the development of gout symptoms.

Common Medications Associated with Drug-Induced Gout

Several classes of medications can lead to drug-induced gout, including:

  • Diuretics: Often used to treat hypertension and heart conditions, diuretics can increase uric acid levels by promoting its reabsorption in the kidneys.
  • Chemotherapy Agents: Certain cancer treatments can lead to rapid cell turnover, releasing purines that are metabolized into uric acid.
  • Immunosuppressants: Medications used to prevent organ transplant rejection or treat autoimmune diseases may also contribute to elevated uric acid levels.

Symptoms

The symptoms of drug-induced gout are similar to those of primary gout and may include:

  • Acute Pain: Sudden onset of severe pain in the affected joint, in this case, the left hand.
  • Swelling and Redness: The joint may appear swollen, red, and warm to the touch.
  • Limited Range of Motion: Affected individuals may experience difficulty moving the joint due to pain and swelling.

Diagnosis

Diagnosis typically involves:

  • Clinical Evaluation: A thorough history and physical examination to assess symptoms and potential medication use.
  • Joint Aspiration: A procedure to extract synovial fluid from the joint for analysis, which can confirm the presence of uric acid crystals.
  • Blood Tests: Measuring serum uric acid levels, although these can be normal during an acute attack.

Management

Management of drug-induced gout involves:

  • Medication Review: Identifying and potentially discontinuing or substituting the offending medication.
  • Uric Acid Lowering Therapy: Medications such as allopurinol or febuxostat may be prescribed to lower uric acid levels.
  • Lifestyle Modifications: Dietary changes, increased hydration, and weight management can help reduce the frequency of gout attacks.

Conclusion

ICD-10 code M10.242 is crucial for accurately documenting cases of drug-induced gout affecting the left hand. Understanding the clinical implications, associated medications, and management strategies is essential for healthcare providers to effectively treat and prevent future gout attacks in patients. Proper coding not only aids in patient care but also ensures appropriate billing and resource allocation in healthcare settings.

Clinical Information

The ICD-10 code M10.242 refers specifically to drug-induced gout affecting the left hand. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for effective diagnosis and management.

Clinical Presentation of Drug-Induced Gout

Drug-induced gout is a type of gout that occurs as a result of certain medications that can elevate uric acid levels in the blood, leading to the formation of urate crystals in the joints. The clinical presentation typically includes:

  • Acute Onset: Patients often experience a sudden onset of pain, which can be severe and debilitating.
  • Affected Joint: In this case, the left hand is specifically affected, which may include the metacarpophalangeal joints (MCP) or interphalangeal joints of the fingers.

Signs and Symptoms

The signs and symptoms of drug-induced gout can vary but generally include:

  • Intense Pain: Patients report excruciating pain in the affected joint, often described as throbbing or burning.
  • Swelling and Inflammation: The joint may appear swollen, red, and warm to the touch, indicating inflammation.
  • Limited Range of Motion: Due to pain and swelling, patients may find it difficult to move the affected fingers or hand.
  • Tophi Formation: In chronic cases, deposits of urate crystals (tophi) may develop, although this is less common in acute presentations.

Patient Characteristics

Certain patient characteristics may predispose individuals to drug-induced gout, including:

  • Medication History: Patients taking diuretics, certain chemotherapy agents, or medications that affect renal function are at higher risk for developing drug-induced gout. Common drugs include thiazide diuretics and some immunosuppressants.
  • Comorbid Conditions: Conditions such as hypertension, diabetes, and chronic kidney disease can increase the likelihood of gout.
  • Demographics: Gout is more prevalent in males than females, particularly in middle-aged and older adults. However, women may also be affected, especially post-menopause when estrogen levels decline.
  • Lifestyle Factors: Obesity, high alcohol consumption, and a diet rich in purines (found in red meat and seafood) can contribute to elevated uric acid levels.

Conclusion

Drug-induced gout, particularly affecting the left hand as indicated by ICD-10 code M10.242, presents with acute pain, swelling, and inflammation in the affected joint. Understanding the signs, symptoms, and patient characteristics associated with this condition is essential for healthcare providers to implement appropriate treatment strategies. Management typically involves addressing the underlying medication causing the gout, along with pain relief and anti-inflammatory measures to alleviate symptoms. Regular monitoring and lifestyle modifications may also be necessary to prevent future episodes.

Approximate Synonyms

ICD-10 code M10.242 refers specifically to "Drug-induced gout, left hand." This classification falls under the broader category of gout, which is a type of inflammatory arthritis characterized by sudden and severe pain, redness, and swelling in the joints. Below are alternative names and related terms associated with this specific code.

Alternative Names for M10.242

  1. Drug-Induced Gout: This term emphasizes that the gout is a result of medication use, distinguishing it from other types of gout that may arise from dietary factors or metabolic issues.

  2. Pharmacological Gout: This term can be used interchangeably with drug-induced gout, highlighting the role of pharmaceuticals in triggering the condition.

  3. Medication-Induced Gout: Similar to drug-induced gout, this term specifies that the condition is caused by the use of certain medications.

  4. Gout Due to Drugs: A straightforward description that indicates the causative relationship between drug use and the onset of gout.

  1. Gout: A general term for the condition characterized by the accumulation of uric acid crystals in the joints, leading to inflammation and pain.

  2. Uric Acid Nephropathy: While not directly synonymous, this term relates to the complications that can arise from high uric acid levels, which may be exacerbated by certain medications.

  3. Arthritis: A broader category that includes various types of joint inflammation, including gout.

  4. Left Hand Gout: This term specifies the affected area, indicating that the gout attack is localized to the left hand.

  5. Acute Gout Attack: This term describes the sudden onset of symptoms associated with gout, which can be triggered by various factors, including drug use.

  6. Chronic Gout: While M10.242 refers to an acute condition, chronic gout can develop if acute attacks are not managed properly.

  7. Hyperuricemia: This term refers to elevated levels of uric acid in the blood, which is a common precursor to gout.

Conclusion

Understanding the alternative names and related terms for ICD-10 code M10.242 can enhance communication among healthcare professionals and improve patient education. Recognizing the specific context of drug-induced gout is crucial for effective diagnosis and treatment, as it allows for targeted management strategies that address both the gout and the underlying medication-related causes. If you have further questions or need additional information, feel free to ask!

Diagnostic Criteria

The diagnosis of drug-induced gout, specifically coded as ICD-10 code M10.242, involves several criteria that healthcare professionals utilize to ensure accurate identification and classification of the condition. Here’s a detailed overview of the diagnostic criteria and considerations for this specific type of gout.

Understanding Drug-Induced Gout

Gout is a form of inflammatory arthritis characterized by the accumulation of uric acid crystals in the joints, leading to sudden and severe pain, redness, and swelling. Drug-induced gout occurs when certain medications elevate uric acid levels in the body, triggering gout attacks. Common medications associated with this condition include diuretics, certain chemotherapy agents, and immunosuppressants.

Diagnostic Criteria for Drug-Induced Gout

1. Clinical Presentation

  • Symptoms: Patients typically present with acute onset of joint pain, often in the left hand or other affected joints. The pain is usually severe and may be accompanied by swelling, redness, and warmth in the affected area[1].
  • Duration and Frequency: The frequency and duration of attacks can vary, but episodes may become more frequent if the underlying cause (i.e., the offending medication) is not addressed[1].

2. Medical History

  • Medication Review: A thorough review of the patient’s medication history is crucial. Identifying any recent changes in medication or the initiation of drugs known to increase uric acid levels is essential for establishing a diagnosis of drug-induced gout[1].
  • Pre-existing Conditions: The presence of other risk factors for gout, such as obesity, renal impairment, or a family history of gout, should also be considered[1].

3. Laboratory Tests

  • Serum Uric Acid Levels: Elevated serum uric acid levels (hyperuricemia) are a key indicator. While not all patients with high uric acid levels will develop gout, levels above 6.8 mg/dL are often associated with the condition[1].
  • Joint Aspiration: In some cases, synovial fluid may be aspirated from the affected joint to look for monosodium urate crystals under polarized light microscopy, confirming the diagnosis of gout[1].

4. Exclusion of Other Conditions

  • Differential Diagnosis: It is important to rule out other forms of arthritis or conditions that may mimic gout, such as pseudogout, septic arthritis, or other inflammatory arthritides. This may involve additional imaging studies or laboratory tests[1].

5. ICD-10 Classification

  • Specificity of Code M10.242: The ICD-10 code M10.242 specifically denotes drug-induced gout affecting the left hand. Accurate coding requires documentation of the specific joint involved and the causal relationship with the medication[3].

Conclusion

Diagnosing drug-induced gout, particularly as classified under ICD-10 code M10.242, requires a comprehensive approach that includes clinical evaluation, medication history, laboratory testing, and exclusion of other conditions. By adhering to these criteria, healthcare providers can ensure accurate diagnosis and appropriate management of this painful condition. If you suspect drug-induced gout, it is advisable to consult a healthcare professional for a thorough assessment and tailored treatment plan.

Treatment Guidelines

Gout is a form of inflammatory arthritis characterized by the accumulation of uric acid crystals in the joints, leading to sudden and severe pain, redness, and swelling. The ICD-10 code M10.242 specifically refers to drug-induced gout affecting the left hand. Understanding the standard treatment approaches for this condition is crucial for effective management.

Understanding Drug-Induced Gout

Drug-induced gout occurs when certain medications elevate uric acid levels in the blood, leading to the formation of crystals in the joints. Common medications associated with this condition include diuretics, certain chemotherapy agents, and immunosuppressants. The left hand, being a common site for gout attacks, can experience significant discomfort and functional impairment during flare-ups.

Standard Treatment Approaches

1. Acute Management of Gout Attacks

The primary goal during an acute gout attack is to relieve pain and inflammation. Standard treatments include:

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Medications such as ibuprofen or naproxen are commonly prescribed to reduce pain and inflammation during an acute attack[1].
  • Colchicine: This medication is effective in reducing gout pain, especially if taken early in the course of an attack. It works by decreasing inflammation caused by uric acid crystals[1].
  • Corticosteroids: For patients who cannot tolerate NSAIDs or colchicine, corticosteroids like prednisone may be used to control inflammation and pain[1].

2. Long-term Management and Prevention

To prevent future gout attacks, especially in cases of drug-induced gout, it is essential to manage uric acid levels effectively:

  • Urate-Lowering Therapy: Medications such as allopurinol or febuxostat are often prescribed to lower uric acid levels in the blood. These medications help prevent the formation of uric acid crystals[1].
  • Lifestyle Modifications: Patients are advised to make dietary changes, such as reducing intake of purine-rich foods (e.g., red meat, shellfish) and alcohol, which can exacerbate gout symptoms. Staying hydrated and maintaining a healthy weight are also important[1][2].
  • Medication Review: It is crucial to review the patient's current medications with their healthcare provider. If a specific drug is identified as the cause of elevated uric acid levels, alternatives may be considered[2].

3. Monitoring and Follow-Up

Regular follow-up appointments are essential to monitor uric acid levels and assess the effectiveness of treatment strategies. Blood tests may be conducted periodically to ensure that uric acid levels remain within the target range, typically below 6 mg/dL[2].

Conclusion

Managing drug-induced gout, particularly in the left hand, involves a combination of acute treatment strategies to alleviate pain during flare-ups and long-term approaches to prevent future attacks. By utilizing NSAIDs, colchicine, or corticosteroids during acute episodes and implementing urate-lowering therapies alongside lifestyle modifications, patients can effectively manage their condition. Regular monitoring and medication reviews are also critical to ensure optimal treatment outcomes. If you suspect drug-induced gout, consulting a healthcare provider for a tailored treatment plan is essential.

Related Information

Description

  • Gout is caused by uric acid accumulation
  • Caused by dietary choices, obesity, medications
  • Inflammation and pain in joints
  • Diuretics increase uric acid levels
  • Chemotherapy agents lead to rapid cell turnover
  • Immunosuppressants contribute to elevated uric acid
  • Acute pain in affected joint
  • Swelling and redness in the joint
  • Limited range of motion due to pain and swelling

Clinical Information

  • Acute onset of severe pain
  • Left hand involvement specifically
  • Intense throbbing or burning pain
  • Swelling and inflammation of affected joint
  • Limited range of motion due to pain and swelling
  • Tophi formation in chronic cases
  • Medications that elevate uric acid levels
  • Diuretics, chemotherapy agents, immunosuppressants
  • Hypertension, diabetes, chronic kidney disease as comorbid conditions
  • Higher prevalence in males post-menopause
  • Obesity, high alcohol consumption, purine-rich diet risk factors

Approximate Synonyms

Diagnostic Criteria

Treatment Guidelines

  • NSAIDs reduce pain and inflammation
  • Colchicine decreases inflammation caused by uric acid crystals
  • Corticosteroids control inflammation and pain
  • Urate-lowering therapy prevents future attacks
  • Lifestyle modifications include dietary changes and hydration
  • Medication review identifies drug causes of elevated uric acid levels
  • Regular monitoring tracks uric acid levels and treatment effectiveness

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