ICD-10: M10.249

Drug-induced gout, unspecified hand

Additional Information

Approximate Synonyms

ICD-10 code M10.249 refers specifically to "Drug-induced gout, unspecified hand." This code is part of the broader classification of gout-related conditions, which can be influenced by various factors, including medications. Below are alternative names and related terms associated with this specific ICD-10 code.

Alternative Names for M10.249

  1. Drug-Induced Gout: This is the primary term that describes gout triggered by medications, which can include diuretics, chemotherapy agents, and other drugs that affect uric acid levels.

  2. Medication-Induced Gout: Similar to drug-induced gout, this term emphasizes the role of medications in precipitating gout attacks.

  3. Pharmacological Gout: This term highlights the connection between pharmacological agents and the onset of gout symptoms.

  4. Gout Due to Drug Therapy: This phrase is often used in clinical settings to specify that the gout condition is a result of therapeutic drug use.

  1. Gout: A general term for a type of arthritis characterized by sudden, severe attacks of pain, redness, and swelling in the joints, often affecting the big toe.

  2. Uric Acid Nephropathy: A condition that can arise from high levels of uric acid, which may be exacerbated by certain medications.

  3. Hyperuricemia: Elevated levels of uric acid in the blood, which can lead to gout. This condition can be drug-induced as well.

  4. Acute Gout Attack: Refers to the sudden onset of gout symptoms, which can be triggered by various factors, including drug use.

  5. Chronic Gout: A long-term condition that may develop from repeated acute attacks, potentially influenced by medication.

  6. Secondary Gout: This term is used to describe gout that occurs as a result of another condition or factor, such as drug use.

  7. Gouty Arthritis: A term that describes the inflammation of joints due to gout, which can be drug-induced.

Conclusion

Understanding the alternative names and related terms for ICD-10 code M10.249 is essential for accurate diagnosis, treatment, and billing in clinical practice. These terms help healthcare professionals communicate effectively about the condition and its underlying causes, particularly when medications are involved. If you need further information on specific medications that can induce gout or additional coding details, feel free to ask!

Description

ICD-10 code M10.249 refers to drug-induced gout, specifically affecting an unspecified hand. This classification falls under the broader category of gout, which is a type of inflammatory arthritis characterized by sudden and severe pain, redness, and swelling in the joints, often due to elevated levels of uric acid in the blood.

Clinical Description of Drug-Induced Gout

Definition and Etiology

Drug-induced gout occurs when certain medications lead to an increase in uric acid levels or interfere with the body's ability to eliminate uric acid. This condition can manifest in patients who may not have a prior history of gout but develop symptoms due to the pharmacological effects of specific drugs. Common medications associated with drug-induced gout include diuretics, certain chemotherapy agents, and medications that affect renal function.

Symptoms

The symptoms of drug-induced gout are similar to those of primary gout and may include:
- Acute joint pain: Often starting suddenly, typically at night.
- Swelling and inflammation: Affected joints may appear swollen and red.
- Limited range of motion: Pain and swelling can restrict movement in the affected joint.

In the case of M10.249, the symptoms are localized to an unspecified hand, which may involve any of the joints in the hand, such as the fingers or wrist.

Diagnosis

Diagnosis of drug-induced gout typically involves:
- Clinical evaluation: A thorough history and physical examination to assess symptoms and potential drug exposure.
- Laboratory tests: Blood tests to measure uric acid levels, and joint fluid analysis may be performed to confirm the presence of monosodium urate crystals.
- Medication review: Identifying any recent changes in medication that could have precipitated the gout attack.

Treatment

Management of drug-induced gout focuses on:
- Discontinuation of the offending drug: If a specific medication is identified as the cause, it should be stopped or replaced with an alternative.
- Medications for symptom relief: Nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or corticosteroids may be prescribed to alleviate pain and inflammation.
- Long-term management: Patients may require urate-lowering therapy if they have recurrent episodes of gout.

Conclusion

ICD-10 code M10.249 is crucial for accurately documenting cases of drug-induced gout affecting the hand. Understanding the clinical implications, symptoms, and treatment options is essential for healthcare providers to manage this condition effectively. Proper coding ensures appropriate treatment and facilitates communication among healthcare professionals regarding patient care.

Clinical Information

Drug-induced gout, classified under ICD-10 code M10.249, refers to a specific type of gout that arises as a result of certain medications. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for effective diagnosis and management.

Clinical Presentation

Overview of Gout

Gout is a form of inflammatory arthritis characterized by the deposition of monosodium urate crystals in joints and tissues due to elevated uric acid levels in the blood. Drug-induced gout specifically occurs when certain medications lead to increased uric acid levels or interfere with its excretion, resulting in acute gout attacks.

Common Medications Associated with Drug-Induced Gout

Several classes of medications can precipitate drug-induced gout, including:
- Diuretics: Often used for hypertension or edema, these can increase uric acid levels by promoting renal retention.
- Chemotherapy agents: Certain cancer treatments can lead to rapid cell turnover, releasing purines that convert to uric acid.
- Immunosuppressants: Medications like cyclosporine can also contribute to elevated uric acid levels.

Signs and Symptoms

Acute Gout Attack

Patients experiencing drug-induced gout may present with the following signs and symptoms:
- Sudden Onset of Pain: Intense pain in the affected joint, often starting at night. The big toe is commonly affected, but in the case of M10.249, the unspecified hand may indicate involvement of any joint in the hand.
- Swelling and Inflammation: The affected joint may appear swollen, red, and warm to the touch.
- Limited Range of Motion: Patients may experience difficulty moving the affected joint due to pain and swelling.
- Tophi Formation: In chronic cases, deposits of urate crystals can form lumps under the skin, known as tophi, although this is less common in acute presentations.

Systemic Symptoms

In some cases, patients may also exhibit systemic symptoms such as:
- Fever: Mild fever may accompany the acute attack.
- Malaise: General feelings of discomfort or unease.

Patient Characteristics

Demographics

  • Age: Gout is more prevalent in middle-aged and older adults, particularly men, due to higher uric acid levels.
  • Gender: Males are more commonly affected than females, although the risk for women increases post-menopause.

Risk Factors

  • Obesity: Increased body weight is associated with higher uric acid production and decreased renal clearance.
  • Diet: High intake of purine-rich foods (e.g., red meat, seafood) and beverages (e.g., beer) can exacerbate gout.
  • Comorbid Conditions: Conditions such as hypertension, diabetes, and kidney disease can increase the risk of developing gout.

Medication History

A thorough medication history is essential in identifying potential drug-induced gout. Patients may have a history of using diuretics, chemotherapy agents, or other medications known to elevate uric acid levels.

Conclusion

Drug-induced gout, particularly as indicated by ICD-10 code M10.249, presents with acute joint pain, swelling, and inflammation, primarily affecting the hand in this case. Understanding the clinical presentation, associated medications, and patient characteristics is vital for healthcare providers to diagnose and manage this condition effectively. Early recognition and modification of the offending medication, along with appropriate treatment for gout, can significantly improve patient outcomes.

Diagnostic Criteria

The diagnosis of drug-induced gout, particularly under the ICD-10 code M10.249, involves specific criteria that healthcare professionals utilize to ensure accurate identification and classification of the condition. Here’s a detailed overview of the criteria and considerations involved in diagnosing this particular type of gout.

Understanding Drug-Induced Gout

Gout is a form of inflammatory arthritis characterized by the accumulation of uric acid crystals in the joints, leading to sudden and severe pain, redness, and swelling. Drug-induced gout occurs when certain medications elevate uric acid levels in the body, triggering gout attacks. Common medications associated with this condition include diuretics, certain chemotherapy agents, and immunosuppressants.

Diagnostic Criteria for Drug-Induced Gout

1. Clinical Presentation

  • Symptoms: Patients typically present with acute onset of joint pain, often in the big toe (podagra), but in the case of M10.249, the unspecified hand is affected. Symptoms may include swelling, redness, and warmth in the affected joint.
  • Duration and Frequency: The frequency and duration of attacks can vary, with some patients experiencing recurrent episodes.

2. Medical History

  • Medication Review: A thorough review of the patient's medication history is crucial. Identification of drugs known to elevate uric acid levels is essential for establishing a diagnosis of drug-induced gout.
  • Pre-existing Conditions: Consideration of any underlying conditions that may predispose the patient to gout, such as renal impairment or metabolic syndrome, is also important.

3. Laboratory Tests

  • Serum Uric Acid Levels: Elevated serum uric acid levels (hyperuricemia) are a key indicator. However, it is important to note that not all patients with elevated uric acid levels will develop gout.
  • Joint Aspiration: In some cases, synovial fluid may be aspirated from the affected joint to check for the presence of monosodium urate crystals, which confirms the diagnosis of gout.

4. Exclusion of Other Conditions

  • Differential Diagnosis: It is essential to rule out other forms of arthritis or joint conditions that may mimic gout, such as pseudogout, septic arthritis, or other inflammatory arthritides.

5. ICD-10 Classification

  • Specificity of Code: The code M10.249 specifically denotes drug-induced gout affecting an unspecified hand. This classification is used when the exact joint affected is not specified, but the drug-induced nature of the gout is confirmed.

Conclusion

Diagnosing drug-induced gout under the ICD-10 code M10.249 requires a comprehensive approach that includes clinical evaluation, medication history, laboratory tests, and exclusion of other conditions. By adhering to these criteria, healthcare providers can accurately identify and manage this condition, ensuring appropriate treatment and care for affected patients. If you have further questions or need additional information on this topic, feel free to ask!

Treatment Guidelines

When addressing the management of drug-induced gout, particularly as classified under ICD-10 code M10.249 (Drug-induced gout, unspecified hand), it is essential to understand both the underlying condition and the treatment strategies available. Gout is a form of inflammatory arthritis characterized by the accumulation of uric acid crystals in the joints, leading to painful episodes. Drug-induced gout can occur due to certain medications that elevate uric acid levels or alter its metabolism.

Understanding Drug-Induced Gout

Causes

Drug-induced gout can be triggered by various medications, including:
- Diuretics: Often used for hypertension or edema, these can increase uric acid levels by promoting renal excretion of water while retaining uric acid.
- Chemotherapy agents: Certain cancer treatments can lead to rapid cell turnover, releasing purines that convert to uric acid.
- Immunosuppressants: Medications like cyclosporine can also elevate uric acid levels.

Symptoms

Patients may experience:
- Sudden and severe pain in the affected joint (in this case, the hand).
- Swelling and redness around the joint.
- Limited range of motion due to pain.

Standard Treatment Approaches

1. Medication Management

The primary goal in treating drug-induced gout is to manage pain and reduce uric acid levels. Common medications include:

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): These are often the first line of treatment to alleviate pain and inflammation. Examples include ibuprofen and naproxen.
  • Colchicine: This medication can be effective in reducing gout flare-ups, particularly if administered early in the attack.
  • Corticosteroids: For patients who cannot tolerate NSAIDs or colchicine, corticosteroids may be prescribed to reduce inflammation.
  • Urate-lowering therapy: If gout is recurrent, medications such as allopurinol or febuxostat may be initiated to lower uric acid levels over the long term.

2. Lifestyle Modifications

In addition to pharmacological treatments, lifestyle changes can significantly impact the management of gout:
- Dietary changes: Reducing intake of purine-rich foods (e.g., red meats, shellfish) and alcohol can help lower uric acid levels.
- Hydration: Increasing fluid intake can assist in flushing uric acid from the body.
- Weight management: Achieving and maintaining a healthy weight can reduce the frequency of gout attacks.

3. Monitoring and Follow-Up

Regular follow-up appointments are crucial to monitor uric acid levels and adjust treatment as necessary. Patients should be educated about recognizing early signs of gout flares and the importance of adhering to prescribed medications.

4. Addressing Underlying Conditions

If the gout is drug-induced, it may be necessary to evaluate the patient's medication regimen. Collaborating with the prescribing physician to consider alternative medications that do not elevate uric acid levels can be beneficial.

Conclusion

Managing drug-induced gout, particularly in the hand, involves a multifaceted approach that includes medication, lifestyle changes, and ongoing monitoring. By addressing both the symptoms and the underlying causes, healthcare providers can help patients achieve better control over their condition and improve their quality of life. Regular communication between patients and healthcare providers is essential to tailor treatment plans effectively and ensure optimal outcomes.

Related Information

Approximate Synonyms

  • Drug-Induced Gout
  • Medication-Induced Gout
  • Pharmacological Gout
  • Gout Due to Drug Therapy
  • Uric Acid Nephropathy
  • Hyperuricemia

Description

  • Acute joint pain at night
  • Swelling and inflammation in joints
  • Limited range of motion due to pain
  • Increased uric acid levels in blood
  • Monosodium urate crystals in joint fluid
  • Medication review for potential culprits
  • Discontinuation of offending medication

Clinical Information

  • Gout occurs due to elevated uric acid levels
  • Monosodium urate crystals deposited in joints
  • Acute gout attacks caused by medications
  • Diuretics increase uric acid levels
  • Chemotherapy agents lead to rapid cell turnover
  • Immunosuppressants contribute to elevated uric acid
  • Sudden onset of intense pain in affected joint
  • Swelling and inflammation in the affected joint
  • Limited range of motion due to pain and swelling
  • Fever and malaise can occur as systemic symptoms
  • Gout more prevalent in middle-aged and older adults
  • Males are more commonly affected than females

Diagnostic Criteria

  • Acute onset of joint pain
  • Inflammation in the big toe (podagra)
  • Elevated serum uric acid levels
  • Hyperuricemia confirmed by lab tests
  • Monosodium urate crystals found in synovial fluid
  • Medications known to elevate uric acid identified
  • Exclusion of other joint conditions

Treatment Guidelines

  • Use NSAIDs for pain relief
  • Administer colchicine early in attack
  • Prescribe corticosteroids if necessary
  • Initiate urate-lowering therapy for recurrent gout
  • Reduce purine-rich food intake
  • Increase fluid intake to flush uric acid
  • Achieve and maintain a healthy weight

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