ICD-10: M86.30

Chronic multifocal osteomyelitis, unspecified site

Additional Information

Clinical Information

Chronic multifocal osteomyelitis (CMO) is a rare and complex bone infection characterized by inflammation and infection in multiple sites of the bone. The ICD-10-CM code M86.30 specifically refers to chronic multifocal osteomyelitis without specifying the site of infection. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for accurate diagnosis and management.

Clinical Presentation

Signs and Symptoms

Patients with chronic multifocal osteomyelitis typically present with a variety of signs and symptoms, which may include:

  • Localized Pain: Patients often report persistent pain in the affected bones, which may be exacerbated by movement or pressure.
  • Swelling and Tenderness: There may be noticeable swelling over the affected areas, accompanied by tenderness upon palpation.
  • Fever and Malaise: Some patients may experience systemic symptoms such as fever, chills, and a general feeling of unwellness (malaise), although these are less common in chronic cases compared to acute osteomyelitis[1][2].
  • Bone Deformities: In some cases, chronic osteomyelitis can lead to deformities or changes in the shape of the affected bones due to ongoing inflammation and bone destruction[3].

Radiological Findings

Imaging studies, particularly X-rays, MRI, or CT scans, may reveal:

  • Bone Lesions: Radiological imaging often shows multiple lesions or areas of bone destruction.
  • Sclerosis and Sequestrum Formation: There may be evidence of bone sclerosis (hardening) and the presence of sequestra (segments of dead bone) in chronic cases[4].

Patient Characteristics

Demographics

Chronic multifocal osteomyelitis can affect individuals of various ages, but it is more commonly seen in:

  • Children and Young Adults: The condition is often diagnosed in pediatric populations, particularly in those with underlying health issues or immunocompromised states[5].
  • Individuals with Comorbidities: Patients with conditions such as diabetes, sickle cell disease, or those undergoing immunosuppressive therapy are at higher risk for developing osteomyelitis[6].

Risk Factors

Several risk factors may predispose individuals to chronic multifocal osteomyelitis, including:

  • Previous Bone Trauma or Surgery: History of trauma or surgical procedures involving the bones can increase susceptibility to infection.
  • Chronic Inflammatory Conditions: Conditions that lead to chronic inflammation may also contribute to the development of osteomyelitis[7].
  • Genetic Factors: Some studies suggest a genetic predisposition may play a role in the susceptibility to chronic bone infections[8].

Conclusion

Chronic multifocal osteomyelitis, coded as M86.30 in the ICD-10-CM, presents with a range of clinical signs and symptoms, primarily localized pain, swelling, and potential systemic effects. The condition is more prevalent in children and individuals with certain risk factors, including underlying health conditions. Accurate diagnosis often requires a combination of clinical evaluation and imaging studies to assess the extent of bone involvement. Understanding these characteristics is essential for healthcare providers to implement effective treatment strategies and improve patient outcomes.

Approximate Synonyms

Chronic multifocal osteomyelitis, classified under ICD-10 code M86.30, is a complex condition characterized by inflammation and infection of the bone at multiple sites. Understanding its alternative names and related terms can enhance clarity in medical documentation and communication. Below are some of the key alternative names and related terms associated with this condition.

Alternative Names

  1. Chronic Recurrent Multifocal Osteomyelitis (CRMO): This term is often used interchangeably with chronic multifocal osteomyelitis, particularly in pediatric populations. CRMO is recognized as a non-bacterial inflammatory bone disease that can lead to recurrent episodes of bone pain and swelling[6].

  2. Multifocal Osteomyelitis: This term emphasizes the multifocal nature of the infection, indicating that multiple areas of the bone are affected, although it may not specify the chronic aspect[6].

  3. Chronic Osteomyelitis: While this term generally refers to long-standing bone infections, it may not capture the multifocal aspect of M86.30. However, it is often used in clinical discussions regarding chronic bone infections[6].

  4. Osteitis: This term refers to inflammation of the bone and can sometimes be used in broader discussions about bone inflammatory conditions, although it does not specifically denote the multifocal nature of M86.30[6].

  1. ICD-10 Code M86.3: This is the broader category under which M86.30 falls, specifically referring to chronic multifocal osteomyelitis. It is important for coding and billing purposes in healthcare settings[4][7].

  2. Osteomyelitis: A general term for bone infection, which can be acute or chronic. It is essential to differentiate between types when discussing treatment and prognosis[6].

  3. Bone Pain: A common symptom associated with chronic multifocal osteomyelitis, often leading to further investigation and diagnosis[6].

  4. Inflammatory Bone Disease: This term encompasses a range of conditions, including chronic multifocal osteomyelitis, that involve inflammation of the bone, often with varying etiologies[6].

  5. CUI C0410422: This is the Concept Unique Identifier (CUI) for chronic recurrent multifocal osteomyelitis in medical databases, which can be useful for research and clinical documentation purposes[6].

Conclusion

Understanding the alternative names and related terms for ICD-10 code M86.30 is crucial for accurate diagnosis, treatment, and communication among healthcare professionals. These terms not only facilitate better understanding of the condition but also aid in the coding and billing processes within healthcare systems. If you have further questions or need more specific information, feel free to ask!

Diagnostic Criteria

Chronic multifocal osteomyelitis (CMO) is a rare bone infection characterized by the presence of multiple lesions, often affecting different sites in the body. The ICD-10 code M86.30 specifically refers to chronic multifocal osteomyelitis without specifying the site of infection. The diagnosis of CMO involves several criteria and considerations, which are essential for accurate coding and treatment.

Diagnostic Criteria for Chronic Multifocal Osteomyelitis (ICD-10 M86.30)

Clinical Presentation

  1. Symptoms: Patients typically present with persistent pain in the affected bones, which may be accompanied by swelling, tenderness, and sometimes fever. The pain is often chronic and may worsen with activity.
  2. History: A thorough medical history is crucial, including any previous infections, trauma, or underlying conditions that may predispose the patient to osteomyelitis.

Imaging Studies

  1. Radiographic Findings: Imaging studies such as X-rays, MRI, or CT scans are essential for diagnosing CMO. These studies may reveal:
    - Bone lesions that appear as areas of lucency or sclerosis.
    - Changes in the medullary cavity and cortical bone.
    - Evidence of bone marrow edema on MRI, which is indicative of inflammation.

  2. Bone Scintigraphy: A bone scan can help identify multifocal lesions, as it shows increased uptake in areas of infection or inflammation.

Laboratory Tests

  1. Blood Tests: Laboratory tests may include:
    - Complete blood count (CBC) to check for signs of infection (e.g., elevated white blood cell count).
    - Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels, which may be elevated in the presence of inflammation.

  2. Microbiological Studies: Cultures from bone biopsies or aspirates can help identify the causative organism, although they may not always yield positive results in chronic cases.

Histopathological Examination

  1. Bone Biopsy: A biopsy of the affected bone may be performed to confirm the diagnosis. Histological examination can reveal:
    - Necrotic bone tissue.
    - Inflammatory cell infiltration, which is characteristic of osteomyelitis.

Exclusion of Other Conditions

  1. Differential Diagnosis: It is important to rule out other conditions that may mimic CMO, such as:
    - Malignancies (e.g., primary bone tumors or metastases).
    - Other infectious processes (e.g., septic arthritis or soft tissue infections).
    - Non-infectious inflammatory conditions (e.g., autoimmune diseases).

Documentation Requirements

  1. ICD-10-CM Guidelines: Accurate documentation is essential for coding M86.30. The documentation should include:
    - Specific symptoms and clinical findings.
    - Results from imaging and laboratory tests.
    - Any relevant history that supports the diagnosis of chronic multifocal osteomyelitis.

Conclusion

The diagnosis of chronic multifocal osteomyelitis (ICD-10 code M86.30) requires a comprehensive approach that includes clinical evaluation, imaging studies, laboratory tests, and possibly histopathological examination. Proper documentation and exclusion of other conditions are critical for accurate diagnosis and treatment planning. Understanding these criteria not only aids in effective patient management but also ensures appropriate coding for healthcare billing and records.

Treatment Guidelines

Chronic multifocal osteomyelitis, classified under ICD-10 code M86.30, is a rare and complex bone infection characterized by the inflammation of bone tissue at multiple sites. This condition can be particularly challenging to treat due to its multifocal nature and the potential for recurrence. Here, we will explore the standard treatment approaches for this condition, including medical, surgical, and supportive therapies.

Overview of Chronic Multifocal Osteomyelitis

Chronic multifocal osteomyelitis typically presents with pain, swelling, and sometimes systemic symptoms like fever. The etiology can be multifactorial, including bacterial infections, autoimmune conditions, or even post-traumatic complications. Diagnosis often involves imaging studies such as MRI or CT scans, along with laboratory tests to identify any underlying infections or inflammatory markers.

Standard Treatment Approaches

1. Antibiotic Therapy

Antibiotic treatment is a cornerstone of managing chronic osteomyelitis. The choice of antibiotics may depend on the suspected or confirmed causative organism. Broad-spectrum antibiotics are often initiated, and therapy may be adjusted based on culture results. Treatment duration can vary but typically lasts several weeks to months, depending on the severity of the infection and the patient's response to therapy[1].

2. Surgical Intervention

In cases where there is significant bone necrosis or abscess formation, surgical intervention may be necessary. This can include:

  • Debridement: Removal of necrotic bone and infected tissue to promote healing and reduce the bacterial load.
  • Bone Grafting: In some cases, bone grafting may be required to restore structural integrity and promote healing in the affected areas.
  • Stabilization: If the infection has compromised the structural integrity of the bone, stabilization procedures may be necessary to prevent fractures[1].

3. Hyperbaric Oxygen Therapy (HBOT)

Hyperbaric oxygen therapy has been explored as an adjunctive treatment for chronic osteomyelitis. HBOT involves breathing 100% oxygen in a pressurized environment, which can enhance oxygen delivery to infected tissues, promote healing, and improve the effectiveness of antibiotics. While evidence supporting its efficacy is still evolving, some studies suggest it may be beneficial in certain cases, particularly when conventional treatments have failed[1][2].

4. Pain Management

Effective pain management is crucial for patients with chronic multifocal osteomyelitis. This may involve:

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): To reduce inflammation and alleviate pain.
  • Opioids: In cases of severe pain, opioids may be prescribed, but their use should be carefully monitored due to the risk of dependency.
  • Physical Therapy: Rehabilitation exercises can help improve function and reduce pain over time[1].

5. Supportive Care

Supportive care is essential in managing chronic osteomyelitis. This includes:

  • Nutritional Support: Ensuring adequate nutrition can help support the immune system and promote healing.
  • Monitoring and Follow-Up: Regular follow-up appointments are necessary to monitor the response to treatment and adjust the management plan as needed.

Conclusion

The management of chronic multifocal osteomyelitis (ICD-10 code M86.30) requires a multidisciplinary approach that combines antibiotic therapy, surgical intervention, and supportive care. While treatment can be complex and lengthy, a tailored approach based on the individual patient's needs and the specific characteristics of the infection can lead to improved outcomes. Ongoing research into adjunctive therapies, such as hyperbaric oxygen therapy, may further enhance treatment options in the future. Regular follow-up and monitoring are essential to ensure effective management and prevent recurrence of the condition[1][2].


References

  1. Clinical guidelines on the management of osteomyelitis.
  2. Studies on the efficacy of hyperbaric oxygen therapy in chronic infections.

Description

Chronic multifocal osteomyelitis, classified under ICD-10 code M86.30, is a specific type of bone infection characterized by the presence of multiple areas of inflammation and infection within the bone. This condition is particularly notable for its chronic nature, which distinguishes it from acute osteomyelitis, and it often affects children and young adults.

Clinical Description

Definition

Chronic multifocal osteomyelitis is a rare, chronic inflammatory bone disease that typically presents with multiple lesions in different bones. Unlike acute osteomyelitis, which is usually caused by a bacterial infection and presents with sudden onset symptoms, chronic multifocal osteomyelitis develops gradually and may not always be associated with systemic symptoms.

Etiology

The exact cause of chronic multifocal osteomyelitis remains unclear, but it is believed to involve a combination of infectious, autoimmune, and possibly genetic factors. Some studies suggest that it may be related to a dysregulated immune response to infections or other stimuli, leading to chronic inflammation in the bone tissue[1].

Symptoms

Patients with chronic multifocal osteomyelitis may experience:
- Localized pain: Often in the affected bones, which can be persistent and may worsen with activity.
- Swelling: In the areas surrounding the affected bones.
- Fever: Although systemic symptoms are less common, some patients may experience low-grade fever.
- Fatigue: General malaise and fatigue can accompany the condition.

Diagnosis

Diagnosis typically involves a combination of clinical evaluation, imaging studies, and laboratory tests:
- Imaging: X-rays, MRI, or CT scans can reveal bone lesions and changes consistent with osteomyelitis.
- Biopsy: In some cases, a biopsy of the affected bone may be necessary to rule out other conditions and confirm the diagnosis.
- Laboratory tests: Blood tests may show elevated inflammatory markers, although they are not specific to osteomyelitis.

Treatment

Management of chronic multifocal osteomyelitis often includes:
- Antibiotic therapy: Prolonged courses of antibiotics may be necessary, especially if an infectious agent is identified.
- Surgical intervention: In cases where there is significant bone destruction or abscess formation, surgical debridement may be required.
- Supportive care: Pain management and physical therapy can help improve function and quality of life.

Conclusion

Chronic multifocal osteomyelitis (ICD-10 code M86.30) is a complex condition that requires a multidisciplinary approach for effective management. Understanding its clinical presentation, diagnostic criteria, and treatment options is crucial for healthcare providers to ensure timely and appropriate care for affected patients. Further research is needed to elucidate the underlying mechanisms and optimize treatment strategies for this challenging condition[1].


[1] Information synthesized from general medical knowledge and clinical guidelines on osteomyelitis.

Related Information

Clinical Information

  • Localized pain in affected bones
  • Swelling and tenderness over affected areas
  • Fever and malaise in some cases
  • Bone deformities due to inflammation
  • Multiple bone lesions on radiological imaging
  • Sclerosis and sequestrum formation on imaging
  • Affects children and young adults primarily
  • Increases risk in individuals with comorbidities
  • Previous bone trauma or surgery increases risk
  • Chronic inflammatory conditions contribute to development

Approximate Synonyms

  • Chronic Recurrent Multifocal Osteomyelitis
  • Multifocal Osteomyelitis
  • Chronic Osteomyelitis
  • Osteitis
  • Bone Pain
  • Inflammatory Bone Disease

Diagnostic Criteria

  • Persistent pain in affected bones
  • Swelling, tenderness, and sometimes fever
  • Previous infections, trauma, or underlying conditions
  • Bone lesions on X-rays, MRI, or CT scans
  • Changes in medullary cavity and cortical bone
  • Evidence of bone marrow edema on MRI
  • Increased uptake on bone scan
  • Elevated white blood cell count
  • Elevated ESR and CRP levels
  • Necrotic bone tissue on biopsy
  • Inflammatory cell infiltration on biopsy

Treatment Guidelines

  • Antibiotic treatment for several weeks to months
  • Surgical intervention for abscess formation or bone necrosis
  • Debridement of infected tissue and necrotic bone
  • Bone grafting to restore structural integrity
  • Stabilization procedures to prevent fractures
  • Hyperbaric oxygen therapy as adjunctive treatment
  • Pain management with NSAIDs, opioids, and physical therapy
  • Nutritional support to promote healing and immune function
  • Regular monitoring and follow-up appointments

Description

  • Rare chronic inflammatory bone disease
  • Multiple lesions in different bones
  • Gradual development, not sudden onset
  • Localized pain in affected bones
  • Swelling around affected bones
  • Low-grade fever in some patients
  • General malaise and fatigue
  • Diagnosis by clinical evaluation and imaging studies

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