ICD-10: M87.177

Osteonecrosis due to drugs, right toe(s)

Additional Information

Description

Osteonecrosis, also known as avascular necrosis, is a condition characterized by the death of bone tissue due to a lack of blood supply. The ICD-10 code M87.177 specifically refers to osteonecrosis caused by drugs, affecting the right toe(s). Below is a detailed clinical description and relevant information regarding this condition.

Clinical Description of Osteonecrosis (ICD-10 Code M87.177)

Definition

Osteonecrosis due to drugs is a form of osteonecrosis that occurs when certain medications disrupt the blood supply to the bone, leading to bone cell death. This condition can result from various pharmacological agents, including corticosteroids, bisphosphonates, and certain chemotherapy drugs.

Etiology

The primary cause of osteonecrosis in this context is the use of specific drugs that can impair blood flow or directly affect bone metabolism. Common drugs associated with this condition include:
- Corticosteroids: Long-term use can lead to fat accumulation in the blood vessels, reducing blood flow to the bones.
- Bisphosphonates: While these are used to treat osteoporosis, they can sometimes lead to osteonecrosis of the jaw and other bones.
- Chemotherapy agents: Certain cancer treatments can also compromise blood supply to the bones.

Symptoms

Patients with osteonecrosis of the right toe(s) may experience:
- Pain: Often the first symptom, which may be mild at first but can become severe over time.
- Swelling: Inflammation around the affected area.
- Limited Range of Motion: Difficulty in moving the toe or foot.
- Joint Stiffness: Especially after periods of inactivity.

Diagnosis

Diagnosis typically involves:
- Clinical Evaluation: A thorough history and physical examination to assess symptoms and medication history.
- Imaging Studies: X-rays, MRI, or CT scans are used to visualize the extent of bone damage and to confirm the diagnosis. MRI is particularly useful in detecting early changes in bone marrow.

Treatment

Management of osteonecrosis due to drugs may include:
- Medication Adjustment: If possible, discontinuing or changing the offending drug.
- Pain Management: Use of analgesics or anti-inflammatory medications.
- Physical Therapy: To improve mobility and strengthen surrounding muscles.
- Surgical Options: In severe cases, procedures such as core decompression, bone grafting, or joint replacement may be necessary.

Prognosis

The prognosis for osteonecrosis varies based on the extent of the disease at diagnosis and the effectiveness of treatment. Early detection and intervention can significantly improve outcomes, while advanced cases may lead to joint collapse and require surgical intervention.

Conclusion

ICD-10 code M87.177 identifies osteonecrosis due to drugs affecting the right toe(s), highlighting the importance of recognizing the potential side effects of certain medications. Clinicians should be vigilant in monitoring patients on high-risk drugs for signs of osteonecrosis, ensuring timely diagnosis and appropriate management to mitigate complications.

Clinical Information

Osteonecrosis, particularly when associated with drug use, is a serious condition that can lead to significant morbidity. The ICD-10 code M87.177 specifically refers to osteonecrosis due to drugs affecting the right toe(s). Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for effective diagnosis and management.

Clinical Presentation

Definition and Pathophysiology

Osteonecrosis, also known as avascular necrosis, occurs when there is a loss of blood supply to a bone, leading to bone death. In the case of M87.177, this condition is induced by pharmacological agents, which can disrupt blood flow or directly affect bone metabolism. Common drugs associated with osteonecrosis include corticosteroids, bisphosphonates, and certain chemotherapy agents[1].

Common Patient Characteristics

Patients who may develop osteonecrosis due to drugs often share certain characteristics:
- Age: Typically affects adults, particularly those aged 30-60 years.
- Gender: More prevalent in males than females.
- Medical History: Patients with a history of long-term corticosteroid use, cancer treatment, or metabolic disorders (e.g., diabetes) are at higher risk[2].
- Lifestyle Factors: Smoking and excessive alcohol consumption can exacerbate the risk of developing osteonecrosis[3].

Signs and Symptoms

Initial Symptoms

The onset of symptoms in osteonecrosis can be insidious. Early signs may include:
- Pain: Often the first symptom, which may be localized to the affected toe(s) and can be described as a dull ache or sharp pain, especially during weight-bearing activities.
- Swelling: Localized swelling around the affected toe(s) may occur as the condition progresses.

Advanced Symptoms

As the disease progresses, symptoms may become more pronounced:
- Limited Range of Motion: Patients may experience difficulty moving the affected toe(s) or foot.
- Joint Stiffness: Stiffness in the toe joints can develop, particularly after periods of inactivity.
- Deformity: In advanced cases, structural changes in the toe(s) may be observed, leading to visible deformities.
- Secondary Symptoms: Patients may also report symptoms related to underlying conditions, such as fatigue or systemic illness, particularly if they are undergoing treatment for cancer or other chronic diseases[4].

Diagnostic Indicators

Diagnosis typically involves a combination of clinical evaluation and imaging studies:
- X-rays: Initial imaging may show subtle changes in bone density or structure.
- MRI: More sensitive than X-rays, MRI can detect early changes in bone marrow and is often used to confirm the diagnosis of osteonecrosis[5].

Conclusion

Osteonecrosis due to drugs, particularly affecting the right toe(s) as indicated by ICD-10 code M87.177, presents with a range of clinical features that can significantly impact a patient's quality of life. Early recognition of symptoms such as localized pain, swelling, and limited mobility is essential for timely intervention. Understanding the patient characteristics and risk factors associated with this condition can aid healthcare providers in identifying at-risk individuals and implementing appropriate management strategies. If you suspect osteonecrosis in a patient, a thorough clinical assessment and imaging studies are critical for accurate diagnosis and treatment planning.


References

  1. ICD-10 International statistical classification of diseases and related health problems.
  2. Total Ankle Arthroplasty - Medical Clinical Policy Bulletins.
  3. Diving and Hyperbaric Medicine.
  4. Millennium Cohort Study First Survey.
  5. Reference to Changes for ICD-10-AM/ACHI/ACS.

Approximate Synonyms

ICD-10 code M87.177 specifically refers to "Osteonecrosis due to drugs, right toe(s)." This condition is characterized by the death of bone tissue due to a lack of blood supply, which in this case is induced by pharmacological agents. Understanding alternative names and related terms can help in better communication and documentation in medical settings. Below are some alternative names and related terms associated with this condition.

Alternative Names

  1. Drug-Induced Osteonecrosis: This term broadly describes osteonecrosis that results from the effects of medications, not limited to the toes.

  2. Medication-Induced Bone Necrosis: Similar to drug-induced osteonecrosis, this term emphasizes the role of medications in causing bone tissue death.

  3. Avascular Necrosis (AVN): While this term is more general, it can be used to describe osteonecrosis resulting from various causes, including drug use. It refers to the death of bone tissue due to a lack of blood supply.

  4. Osteonecrosis of the Right Toe: This is a more straightforward description that specifies the location of the osteonecrosis.

  5. Necrosis of Bone due to Pharmacological Agents: This term highlights the causative factor (pharmacological agents) leading to the condition.

  1. ICD-10 Codes: Other related ICD-10 codes include:
    - M87.17: Osteonecrosis due to drugs, unspecified site.
    - M87.874: Other osteonecrosis, right foot, which may encompass broader conditions affecting the foot.

  2. Pharmacological Agents: This term refers to the various drugs that can lead to osteonecrosis, such as corticosteroids, bisphosphonates, and certain chemotherapy agents.

  3. Bone Marrow Edema: This condition often accompanies osteonecrosis and refers to the accumulation of fluid in the bone marrow, which can be a precursor to osteonecrosis.

  4. Chronic Pain: Patients with osteonecrosis often experience chronic pain in the affected area, which is a significant symptom associated with the condition.

  5. Joint Dysfunction: Osteonecrosis can lead to joint problems, particularly if the necrosis affects the joints, resulting in limited mobility and function.

  6. Surgical Intervention: In severe cases, terms like "core decompression" or "joint replacement" may be relevant, as these are potential treatments for advanced osteonecrosis.

Conclusion

Understanding the alternative names and related terms for ICD-10 code M87.177 is crucial for healthcare professionals in accurately diagnosing, documenting, and discussing the condition. This knowledge aids in effective communication among medical teams and enhances patient care by ensuring clarity in treatment plans and medical records. If you need further information on treatment options or management strategies for osteonecrosis, feel free to ask!

Diagnostic Criteria

Osteonecrosis, particularly when associated with drug use, is a serious condition that can lead to significant morbidity. The ICD-10 code M87.177 specifically refers to osteonecrosis due to drugs affecting the right toe(s). Understanding the diagnostic criteria for this condition is crucial for accurate coding and treatment.

Overview of Osteonecrosis

Osteonecrosis, also known as avascular necrosis, occurs when blood flow to a bone is disrupted, leading to bone death. This condition can result from various factors, including trauma, certain medical conditions, and the use of specific medications. In the case of M87.177, the focus is on osteonecrosis induced by pharmacological agents.

Diagnostic Criteria for M87.177

1. Clinical History

  • Medication Use: A detailed history of the patient's medication use is essential. Certain drugs, particularly corticosteroids and bisphosphonates, have been linked to osteonecrosis. The clinician should document the type, dosage, and duration of drug therapy.
  • Symptoms: Patients typically present with pain in the affected area, which may be exacerbated by weight-bearing activities. The pain can be gradual or sudden, depending on the extent of the necrosis.

2. Physical Examination

  • Local Examination: The clinician should perform a thorough examination of the right toe(s) to assess for tenderness, swelling, and any range of motion limitations. Signs of inflammation or deformity may also be present.

3. Imaging Studies

  • X-rays: Initial imaging often includes X-rays, which may show changes in bone density or structural integrity. However, early stages of osteonecrosis may not be visible on X-rays.
  • MRI: Magnetic Resonance Imaging (MRI) is the gold standard for diagnosing osteonecrosis. It can detect early changes in the bone marrow and identify areas of necrosis before they become apparent on X-rays. MRI findings may include a "double-line sign," indicating the presence of necrotic bone.

4. Differential Diagnosis

  • It is crucial to rule out other conditions that may mimic osteonecrosis, such as infections, tumors, or other forms of arthritis. This may involve additional imaging or laboratory tests.

5. Histological Examination

  • In some cases, a biopsy may be performed to confirm the diagnosis, especially if the clinical and imaging findings are inconclusive. Histological examination can reveal necrotic bone and marrow changes consistent with osteonecrosis.

Conclusion

The diagnosis of osteonecrosis due to drugs, specifically coded as M87.177, requires a comprehensive approach that includes a thorough clinical history, physical examination, and appropriate imaging studies. Understanding the patient's medication history is particularly important, as it directly influences the diagnosis and subsequent management. Early detection and intervention are critical to prevent further complications and preserve joint function. If you have further questions or need additional information on this topic, feel free to ask!

Treatment Guidelines

Osteonecrosis, particularly when classified under ICD-10 code M87.177, refers to the death of bone tissue due to a lack of blood supply, specifically in the right toe(s) and as a result of drug-induced factors. This condition can lead to significant pain and functional impairment, necessitating a comprehensive treatment approach. Below, we explore standard treatment strategies for managing osteonecrosis due to drugs.

Understanding Osteonecrosis Due to Drugs

Osteonecrosis can occur as a side effect of certain medications, particularly corticosteroids and bisphosphonates, which are commonly used in the treatment of various conditions, including autoimmune diseases and osteoporosis. The pathophysiology involves the disruption of blood flow to the bone, leading to bone cell death and subsequent structural collapse if not addressed promptly[1].

Standard Treatment Approaches

1. Conservative Management

Pain Management

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): These are often the first line of treatment to alleviate pain and reduce inflammation associated with osteonecrosis[2].
  • Corticosteroids: While these can exacerbate osteonecrosis, they may be used judiciously in some cases to manage severe pain.

Activity Modification

  • Weight Bearing Restrictions: Patients are often advised to limit weight-bearing activities on the affected toe to reduce stress on the bone and prevent further damage[3].
  • Assistive Devices: The use of crutches or a walking boot can help offload pressure from the affected area.

2. Physical Therapy

Physical therapy can play a crucial role in rehabilitation. A tailored program may include:
- Range of Motion Exercises: To maintain joint flexibility and prevent stiffness.
- Strengthening Exercises: To support surrounding muscles and improve overall function without stressing the affected bone[4].

3. Surgical Interventions

If conservative measures fail to provide relief or if the condition progresses, surgical options may be considered:

Core Decompression

  • This procedure involves removing a portion of the inner bone to reduce pressure and improve blood flow to the affected area. It is often indicated in early stages of osteonecrosis[5].

Bone Grafting

  • In cases where significant bone loss has occurred, bone grafting may be performed to replace the necrotic bone with healthy bone tissue, promoting healing and structural integrity[6].

Joint Replacement

  • In advanced cases where the joint is severely damaged, total joint replacement may be necessary to restore function and alleviate pain[7].

4. Pharmacological Interventions

Bisphosphonates

  • These medications may be used to help manage bone density and potentially slow the progression of osteonecrosis, although their effectiveness specifically for drug-induced cases is still under investigation[8].

Anticoagulants

  • In some cases, anticoagulants may be prescribed to improve blood flow, particularly if there is an underlying vascular issue contributing to the osteonecrosis[9].

5. Monitoring and Follow-Up

Regular follow-up appointments are essential to monitor the progression of the condition and the effectiveness of the treatment plan. Imaging studies, such as MRI or X-rays, may be utilized to assess changes in the bone structure over time[10].

Conclusion

The management of osteonecrosis due to drugs, particularly in the right toe(s) as indicated by ICD-10 code M87.177, requires a multifaceted approach tailored to the individual patient's needs. Early intervention with conservative measures can often prevent the need for more invasive procedures. However, in cases where conservative treatment is insufficient, surgical options may provide significant relief and restore function. Continuous monitoring and adjustments to the treatment plan are crucial for optimal outcomes. If you suspect osteonecrosis or are experiencing symptoms, consulting a healthcare professional for a comprehensive evaluation and personalized treatment plan is essential.


References

  1. ICD-10 International statistical classification of diseases and related health problems.
  2. Billing and Coding: Outpatient Physical Therapy.
  3. Core Decompression for Avascular Necrosis.
  4. Facilitating Cross National Comparisons of Indicators for Health.
  5. Total Ankle Arthroplasty - Medical Clinical Policy Bulletins.
  6. ICD-10-CM Diagnosis Code M87.177 - Osteonecrosis due to drugs, right toe(s).
  7. ICD-10-CM Code for Osteonecrosis due to drugs, right toe(s) M87.177.
  8. 2025 ICD-10-CM Codes M87*: Osteonecrosis.
  9. Hyperbaric Oxygen Therapy and Topical Treatments.
  10. SEARCH MOP - Section 20 Mortality Surveillance.

Related Information

Description

  • Lack of blood supply causes bone death
  • Drugs impair blood flow or affect bone metabolism
  • Pain is often first symptom and can worsen
  • Swelling, limited range of motion, joint stiffness occur
  • Diagnosis involves clinical evaluation and imaging studies
  • Treatment includes medication adjustment, pain management
  • Surgical options available for severe cases

Clinical Information

  • Osteonecrosis occurs due to blood supply loss
  • Condition is induced by pharmacological agents
  • Corticosteroids, bisphosphonates, and chemotherapy agents are common causes
  • Typically affects adults aged 30-60 years
  • More prevalent in males than females
  • History of long-term corticosteroid use increases risk
  • Smoking and excessive alcohol consumption exacerbate risk
  • Initial symptoms include localized pain and swelling
  • Advanced symptoms include limited range of motion and deformity
  • Diagnosis involves clinical evaluation and imaging studies
  • X-rays show subtle changes in bone density or structure
  • MRI detects early changes in bone marrow

Approximate Synonyms

  • Drug-Induced Osteonecrosis
  • Medication-Induced Bone Necrosis
  • Avascular Necrosis (AVN)
  • Osteonecrosis of the Right Toe
  • Necrosis of Bone due to Pharmacological Agents

Diagnostic Criteria

  • Medication use is a primary factor
  • Pain in the affected area is common
  • Tenderness and swelling are typical signs
  • X-rays may show changes in bone density
  • MRI is the gold standard for diagnosis
  • Double-line sign indicates necrotic bone
  • Histological examination confirms the diagnosis

Treatment Guidelines

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
  • Corticosteroids
  • Weight Bearing Restrictions
  • Assistive Devices
  • Range of Motion Exercises
  • Strengthening Exercises
  • Core Decompression
  • Bone Grafting
  • Joint Replacement
  • Bisphosphonates
  • Anticoagulants

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