ICD-10: O14.13

Severe pre-eclampsia, third trimester

Additional Information

Description

Severe pre-eclampsia is a serious pregnancy complication characterized by high blood pressure and signs of damage to other organ systems, most commonly the liver and kidneys. The ICD-10 code O14.13 specifically refers to severe pre-eclampsia occurring in the third trimester of pregnancy.

Clinical Description of Severe Pre-eclampsia

Definition

Severe pre-eclampsia is defined as a condition that typically arises after the 20th week of gestation and is marked by the following criteria:
- Blood Pressure: Systolic blood pressure of 160 mm Hg or higher, or diastolic blood pressure of 110 mm Hg or higher.
- Proteinuria: Significant protein in the urine, often defined as 300 mg or more in a 24-hour urine collection or a protein/creatinine ratio of 0.3 or higher.
- Organ Dysfunction: Evidence of dysfunction in one or more organ systems, which may include:
- Elevated liver enzymes (indicating liver damage)
- Low platelet count (thrombocytopenia)
- Renal impairment (elevated creatinine levels)
- Neurological symptoms (such as severe headaches or visual disturbances)

Symptoms

Patients with severe pre-eclampsia may present with various symptoms, including:
- Severe headaches
- Visual disturbances (e.g., blurred vision, seeing spots)
- Upper abdominal pain, particularly in the right upper quadrant
- Nausea or vomiting
- Sudden swelling of the hands and face
- Shortness of breath due to pulmonary edema

Risk Factors

Several factors may increase the risk of developing severe pre-eclampsia, including:
- First-time pregnancy
- History of pre-eclampsia in previous pregnancies
- Multiple gestations (twins, triplets, etc.)
- Obesity
- Chronic hypertension or kidney disease
- Age (younger than 20 or older than 35)

Diagnosis and Management

Diagnosis

The diagnosis of severe pre-eclampsia is typically made based on clinical evaluation and laboratory tests. Key diagnostic steps include:
- Monitoring blood pressure regularly.
- Urinalysis to check for proteinuria.
- Blood tests to assess liver function, kidney function, and platelet count.

Management

Management of severe pre-eclampsia often involves:
- Hospitalization: Patients are usually admitted to a hospital for close monitoring.
- Medications: Antihypertensive medications may be administered to control blood pressure. Magnesium sulfate is often used to prevent seizures (eclampsia).
- Delivery: The definitive treatment for severe pre-eclampsia is delivery of the baby, which may be indicated if the condition is severe or worsening. The timing of delivery is critical and is often determined by the gestational age and the severity of the mother's condition.

Conclusion

ICD-10 code O14.13 captures the critical nature of severe pre-eclampsia in the third trimester, highlighting the need for prompt diagnosis and management to prevent complications for both the mother and the fetus. Early recognition and intervention are essential to improve outcomes in affected pregnancies. Regular prenatal care and monitoring are vital for identifying risk factors and managing conditions like pre-eclampsia effectively.

Clinical Information

Severe pre-eclampsia is a serious condition that can occur during pregnancy, particularly in the third trimester. It is classified under the ICD-10 code O14.13, which specifically denotes severe pre-eclampsia occurring in the third trimester. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with this condition is crucial for timely diagnosis and management.

Clinical Presentation

Severe pre-eclampsia typically manifests after the 20th week of gestation and is characterized by the following clinical features:

  • Hypertension: Blood pressure readings of 160/110 mmHg or higher on two separate occasions at least four hours apart are indicative of severe pre-eclampsia[1].
  • Proteinuria: The presence of significant protein in the urine, often defined as 5 grams or more in a 24-hour urine collection or a protein/creatinine ratio of 0.3 or higher[2].
  • End-organ dysfunction: This may include elevated liver enzymes, renal impairment, or neurological symptoms such as severe headaches or visual disturbances[3].

Signs and Symptoms

Patients with severe pre-eclampsia may exhibit a range of signs and symptoms, including:

  • Severe headaches: Often described as the worst headache ever experienced, which may not respond to typical pain relief measures[4].
  • Visual disturbances: These can include blurred vision, seeing spots, or temporary loss of vision[5].
  • Epigastric or right upper quadrant pain: This may indicate liver involvement and is often associated with liver swelling or rupture[6].
  • Nausea and vomiting: These symptoms can occur, particularly in conjunction with other signs of severe pre-eclampsia[7].
  • Swelling: While mild edema can be common in pregnancy, sudden or severe swelling of the hands, feet, or face may indicate worsening pre-eclampsia[8].
  • Shortness of breath: This may occur due to pulmonary edema, a serious complication of severe pre-eclampsia[9].

Patient Characteristics

Certain patient characteristics may increase the risk of developing severe pre-eclampsia:

  • First-time pregnancy: Women who are pregnant for the first time are at a higher risk compared to those who have had previous pregnancies[10].
  • History of pre-eclampsia: A personal or family history of pre-eclampsia or other hypertensive disorders in pregnancy can increase risk[11].
  • Obesity: Higher body mass index (BMI) is associated with an increased risk of developing pre-eclampsia[12].
  • Multiple gestations: Women carrying twins or more are at a greater risk for severe pre-eclampsia[13].
  • Chronic hypertension or renal disease: Pre-existing conditions can predispose women to develop severe pre-eclampsia during pregnancy[14].
  • Age: Women over the age of 35 or under 20 are at increased risk[15].

Conclusion

Severe pre-eclampsia is a critical condition that requires careful monitoring and management, particularly in the third trimester of pregnancy. Recognizing the clinical presentation, signs, symptoms, and risk factors associated with this condition is essential for healthcare providers to ensure the safety of both the mother and the fetus. Early intervention can significantly reduce the risk of complications, including progression to eclampsia, which can have severe consequences for both mother and child. Regular prenatal care and monitoring of blood pressure and urine protein levels are vital components of managing pregnancies at risk for severe pre-eclampsia.

Approximate Synonyms

Severe pre-eclampsia, particularly in the third trimester, is a significant condition in obstetrics that requires precise coding for medical records and billing. The ICD-10 code O14.13 specifically identifies this condition, but there are several alternative names and related terms that can be associated with it. Understanding these terms can enhance clarity in medical documentation and communication among healthcare providers.

Alternative Names for Severe Pre-eclampsia

  1. Severe Preeclampsia: This is a direct synonym for O14.13, emphasizing the severity of the condition.
  2. Severe Gestational Hypertension: While not identical, this term is often used interchangeably in clinical settings to describe severe hypertension during pregnancy, which can lead to pre-eclampsia.
  3. Eclampsia Preceding Severe Preeclampsia: In some contexts, this term may be used to describe the progression from severe pre-eclampsia to eclampsia, although it is technically a different condition.
  1. Hypertensive Disorders of Pregnancy: This broader category includes various conditions such as gestational hypertension, mild pre-eclampsia, and severe pre-eclampsia, as well as eclampsia.
  2. O14.1: This is the general code for pre-eclampsia, which encompasses both mild and severe forms, with O14.13 being the specific code for severe cases in the third trimester.
  3. Complications of Pregnancy: Severe pre-eclampsia is often classified under complications that can arise during pregnancy, affecting both maternal and fetal health.
  4. Maternal Hypertension: This term refers to high blood pressure in pregnant women and is a key factor in diagnosing pre-eclampsia.
  5. Third Trimester Hypertension: This term specifically refers to hypertension occurring in the third trimester, which is critical for identifying cases of severe pre-eclampsia.

Clinical Context

Severe pre-eclampsia is characterized by high blood pressure and signs of damage to other organ systems, often occurring after the 20th week of pregnancy. It can lead to serious complications for both the mother and the fetus, making accurate coding essential for treatment and management. The use of the correct ICD-10 code, such as O14.13, ensures that healthcare providers can effectively communicate the severity of the condition and facilitate appropriate care.

Conclusion

In summary, while the ICD-10 code O14.13 specifically denotes severe pre-eclampsia in the third trimester, various alternative names and related terms exist that can aid in understanding and documenting this condition. Familiarity with these terms is crucial for healthcare professionals involved in obstetric care, as it enhances communication and ensures accurate medical records.

Diagnostic Criteria

Severe pre-eclampsia is a serious condition that can occur during pregnancy, particularly in the third trimester. The diagnosis of severe pre-eclampsia, represented by the ICD-10 code O14.13, is based on specific clinical criteria. Below, we outline the key diagnostic criteria and considerations for this condition.

Diagnostic Criteria for Severe Pre-eclampsia

1. Hypertension

  • Blood Pressure Measurements: Severe pre-eclampsia is characterized by elevated blood pressure readings. Specifically, a diagnosis is made when the systolic blood pressure is 160 mm Hg or higher, or the diastolic blood pressure is 110 mm Hg or higher, measured on two occasions at least four hours apart[1][2].

2. Proteinuria

  • Protein Levels: The presence of protein in the urine is a critical diagnostic criterion. Severe pre-eclampsia is indicated by proteinuria of 3+ or greater on a dipstick test, or a 24-hour urine collection showing more than 5 grams of protein[3][4].

3. Signs of End-Organ Dysfunction

  • Laboratory and Clinical Findings: The diagnosis may also involve evidence of end-organ dysfunction, which can include:
    • Elevated liver enzymes (e.g., AST or ALT levels greater than twice the upper limit of normal).
    • Renal impairment, indicated by elevated serum creatinine levels (greater than 1.1 mg/dL or a doubling of the baseline).
    • Thrombocytopenia (platelet count less than 100,000 cells/mm³).
    • Pulmonary edema or new-onset visual disturbances[2][5].

4. Symptoms

  • Clinical Symptoms: Patients may present with symptoms such as severe headaches, visual changes (e.g., blurred vision, seeing spots), upper abdominal pain, or sudden swelling of the hands and face. These symptoms can indicate worsening of the condition and should be evaluated in conjunction with laboratory findings[3][4].

Additional Considerations

1. Timing of Diagnosis

  • Third Trimester Focus: The diagnosis of severe pre-eclampsia specifically pertains to the third trimester of pregnancy, typically defined as starting from 28 weeks gestation until delivery[1][2].

2. Differential Diagnosis

  • Exclusion of Other Conditions: It is essential to differentiate severe pre-eclampsia from other hypertensive disorders of pregnancy, such as gestational hypertension and chronic hypertension, to ensure appropriate management and treatment[5][6].

3. Management Implications

  • Immediate Care: The diagnosis of severe pre-eclampsia necessitates close monitoring and often immediate medical intervention, which may include antihypertensive medications and consideration for delivery, depending on the gestational age and severity of the condition[4][5].

Conclusion

The diagnosis of severe pre-eclampsia (ICD-10 code O14.13) is based on a combination of elevated blood pressure, significant proteinuria, and signs of end-organ dysfunction, along with clinical symptoms. Accurate diagnosis is crucial for the timely management of this potentially life-threatening condition, ensuring the safety of both the mother and the fetus. If you have further questions or need more detailed information, feel free to ask!

Treatment Guidelines

Severe pre-eclampsia, classified under ICD-10 code O14.13, is a serious condition that can occur during pregnancy, typically after the 20th week. It is characterized by high blood pressure and signs of damage to other organ systems, often the kidneys. The management of severe pre-eclampsia is critical to ensure the health of both the mother and the fetus. Below, we explore standard treatment approaches for this condition.

Initial Assessment and Monitoring

Clinical Evaluation

Upon diagnosis of severe pre-eclampsia, a thorough clinical evaluation is essential. This includes:
- Blood Pressure Monitoring: Continuous monitoring of blood pressure is crucial, as severe hypertension can lead to complications such as stroke.
- Laboratory Tests: Blood tests to assess liver function, kidney function, and platelet count are necessary to evaluate the severity of the condition and to monitor for complications like HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelet count) [1].

Fetal Monitoring

Fetal well-being must also be assessed through:
- Ultrasound: To evaluate fetal growth and amniotic fluid levels.
- Non-Stress Tests: To monitor fetal heart rate and response to movements, ensuring the fetus is not in distress [2].

Medical Management

Antihypertensive Therapy

To manage high blood pressure, several antihypertensive medications may be used, including:
- Labetalol: A common first-line treatment due to its efficacy and safety profile in pregnancy.
- Hydralazine: Often used for acute management of severe hypertension.
- Nifedipine: A calcium channel blocker that can be used for chronic management [3].

Magnesium Sulfate

Magnesium sulfate is administered to prevent seizures (eclampsia) and is a critical component of the treatment protocol. It is typically given intravenously and requires monitoring for signs of magnesium toxicity, such as respiratory depression or decreased reflexes [4].

Delivery Planning

Timing and Mode of Delivery

The definitive treatment for severe pre-eclampsia is delivery. The timing and method of delivery depend on several factors:
- Gestational Age: If the fetus is viable (generally after 34 weeks), delivery is often recommended to prevent further maternal and fetal complications.
- Maternal and Fetal Condition: If the mother's condition deteriorates or if there are signs of fetal distress, immediate delivery may be necessary, regardless of gestational age [5].

Induction of Labor

If the decision is made to deliver, labor may be induced using medications such as oxytocin or prostaglandins, especially if the cervix is not favorable for spontaneous labor [6].

Postpartum Care

Monitoring

Postpartum monitoring is essential, as the risk of complications can persist. Blood pressure should be monitored closely, and magnesium sulfate may be continued for 24 hours after delivery to prevent seizures [7].

Follow-Up

Patients should have follow-up appointments to monitor blood pressure and assess recovery. Education on recognizing symptoms of postpartum pre-eclampsia or eclampsia is also important for patient safety [8].

Conclusion

The management of severe pre-eclampsia (ICD-10 code O14.13) involves a comprehensive approach that includes careful monitoring, medical management of hypertension, administration of magnesium sulfate, and planning for timely delivery. Postpartum care is equally important to ensure the health and safety of the mother and the newborn. Early recognition and intervention are key to minimizing risks associated with this serious condition.

For further information or specific case management, consulting with a maternal-fetal medicine specialist is recommended.


References

  1. Clinical Policy: Ultrasound in Pregnancy.
  2. A Guide to Obstetrical Coding.
  3. Development and Validation of ICD-10-CM-based Guidelines.
  4. Home Uterine Activity Monitoring (HUAM) - MCS.
  5. TexasAIM HTN Family of Measures.
  6. FY2022 April1 update ICD-10-CM Guidelines.
  7. CG-MED-42 Maternity Ultrasound in the Outpatient Setting.
  8. Development and Validation of ICD-10-CM-based Guidelines.

Related Information

Description

  • High blood pressure after 20 weeks gestation
  • Significant protein in urine
  • Organ dysfunction including liver damage
  • Elevated creatinine levels or renal impairment
  • Severe headaches and visual disturbances
  • Upper abdominal pain and nausea
  • Shortness of breath due to pulmonary edema

Clinical Information

  • Hypertension: Blood pressure above 160/110 mmHg
  • Proteinuria: Significant protein in the urine
  • End-organ dysfunction: Liver, renal, or neurological impairment
  • Severe headaches: Worst headache ever experienced
  • Visual disturbances: Blurred vision, spots, or temporary loss of vision
  • Epigastric pain: Indicating liver involvement
  • Nausea and vomiting: Accompanying severe pre-eclampsia symptoms
  • Swelling: Sudden or severe swelling in hands, feet, or face
  • Shortness of breath: Due to pulmonary edema
  • First-time pregnancy: Higher risk compared to repeat pregnancies
  • History of pre-eclampsia: Increased personal or family risk
  • Obesity: Associated with increased BMI risk
  • Multiple gestations: Greater risk for severe pre-eclampsia
  • Chronic hypertension or renal disease: Predisposing factors

Approximate Synonyms

  • Severe Preeclampsia
  • Severe Gestational Hypertension
  • Eclampsia Preceding Severe Preeclampsia
  • Hypertensive Disorders of Pregnancy
  • Pre-eclampsia
  • Complications of Pregnancy
  • Maternal Hypertension
  • Third Trimester Hypertension

Diagnostic Criteria

  • Systolic BP ≥ 160 mm Hg
  • Diastolic BP ≥ 110 mm Hg
  • Proteinuria of 3+ or >5 grams
  • Elevated liver enzymes (AST/ALT >2x normal)
  • Renal impairment (serum creatinine >1.1 mg/dL)
  • Thrombocytopenia (<100,000 cells/mm³)
  • Pulmonary edema or visual disturbances

Treatment Guidelines

  • Monitor blood pressure continuously
  • Conduct laboratory tests for liver function, kidney function, and platelet count
  • Use ultrasound to evaluate fetal growth and amniotic fluid levels
  • Perform non-stress tests to monitor fetal heart rate
  • Administer labetalol as first-line antihypertensive treatment
  • Use magnesium sulfate to prevent seizures (eclampsia)
  • Deliver mother via induction of labor or cesarean section if necessary
  • Monitor blood pressure closely in postpartum period

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.