ICD-10: O41.12

Chorioamnionitis

Additional Information

Description

Chorioamnionitis, classified under ICD-10 code O41.12, refers to an infection of the chorion and amniotic fluid surrounding the fetus during pregnancy. This condition is significant due to its potential complications for both the mother and the newborn. Below is a detailed clinical description and relevant information regarding this diagnosis.

Clinical Description of Chorioamnionitis

Definition

Chorioamnionitis is defined as an inflammation of the fetal membranes (chorion and amnion) due to infection. It typically occurs when bacteria ascend from the lower genital tract into the amniotic cavity, leading to an inflammatory response. This condition is often associated with prolonged rupture of membranes and can occur before or during labor.

Etiology

The infection can be caused by a variety of microorganisms, including:
- Bacteria: Common pathogens include Group B Streptococcus, Escherichia coli, and other anaerobic bacteria.
- Viral and fungal infections: Although less common, these can also contribute to chorioamnionitis.

Risk Factors

Several factors increase the risk of developing chorioamnionitis:
- Prolonged rupture of membranes (more than 18 hours before delivery)
- Multiple vaginal examinations during labor
- Internal fetal monitoring
- Maternal fever during labor
- History of urinary tract infections

Symptoms

Clinical manifestations of chorioamnionitis may include:
- Maternal fever (often >100.4°F or 38°C)
- Tachycardia in the mother and fetus
- Uterine tenderness
- Foul-smelling amniotic fluid
- Increased white blood cell count

Diagnosis

Diagnosis is primarily clinical, based on maternal symptoms and signs. Laboratory tests may include:
- Blood cultures to identify the causative organism
- Complete blood count (CBC) to assess for leukocytosis
- Amniotic fluid analysis, if necessary, to confirm infection.

Complications

Chorioamnionitis can lead to several serious complications, including:
- For the mother: Increased risk of postpartum infections, sepsis, and longer recovery times.
- For the fetus/newborn: Increased risk of preterm birth, respiratory distress syndrome, sepsis, and neurological complications.

ICD-10 Code O41.12

Code Details

  • ICD-10 Code: O41.12
  • Description: Chorioamnionitis due to infection
  • Classification: This code falls under the category of "Other complications of labor and delivery" and is specifically used to document cases of chorioamnionitis that are not specified as acute or chronic.
  • O41.1290: Chorioamnionitis, unspecified, which may be used when the specific type of chorioamnionitis is not documented.
  • O41.1230: Acute chorioamnionitis, which may be used when the acute nature of the infection is emphasized.

Conclusion

Chorioamnionitis is a critical condition that requires prompt diagnosis and management to mitigate risks to both the mother and the newborn. The ICD-10 code O41.12 is essential for accurate medical coding and billing, ensuring that healthcare providers can effectively communicate the presence of this condition in clinical settings. Proper identification and treatment of chorioamnionitis can significantly improve outcomes for affected patients.

Clinical Information

Chorioamnionitis, classified under ICD-10-CM code O41.12, is an infection of the fetal membranes (chorion and amnion) that can significantly impact both maternal and neonatal health. Understanding its clinical presentation, signs, symptoms, and patient characteristics is crucial for timely diagnosis and management.

Clinical Presentation

Chorioamnionitis typically presents during labor or shortly after the rupture of membranes. The condition can be acute or chronic, with acute chorioamnionitis being more common. Clinicians should be vigilant for signs of infection, especially in patients with prolonged rupture of membranes or other risk factors.

Signs and Symptoms

The clinical signs and symptoms of chorioamnionitis can vary, but common indicators include:

  • Maternal Fever: A temperature of 38°C (100.4°F) or higher is a hallmark sign of chorioamnionitis. This fever may be accompanied by chills and malaise[1].
  • Tachycardia: Increased heart rate in the mother (greater than 100 beats per minute) and the fetus (greater than 160 beats per minute) can indicate infection[2].
  • Uterine Tenderness: The mother may experience tenderness upon palpation of the abdomen, which can suggest inflammation of the membranes[3].
  • Foul-Smelling Amniotic Fluid: The presence of malodorous fluid can be a significant indicator of infection[4].
  • Increased Maternal Heart Rate: Tachycardia in the mother can be a response to infection and is often assessed alongside other vital signs[5].

Additional Symptoms

Other symptoms that may accompany chorioamnionitis include:

  • Nausea and Vomiting: These gastrointestinal symptoms can occur due to systemic infection.
  • Leukocytosis: An elevated white blood cell count is often observed in laboratory tests, indicating an immune response to infection[6].
  • Signs of Preterm Labor: In some cases, chorioamnionitis may present with contractions or other signs of labor, particularly in preterm pregnancies[7].

Patient Characteristics

Certain patient characteristics and risk factors are associated with an increased likelihood of developing chorioamnionitis:

  • Prolonged Rupture of Membranes: The risk increases significantly if the membranes have been ruptured for more than 18 hours before delivery[8].
  • Multiple Vaginal Examinations: Frequent examinations during labor can introduce bacteria into the uterine environment, raising the risk of infection[9].
  • Internal Fetal Monitoring: The use of internal monitors can also increase the risk of chorioamnionitis due to potential bacterial introduction[10].
  • Maternal Factors: Conditions such as obesity, diabetes, and a history of chorioamnionitis in previous pregnancies can predispose women to this infection[11].
  • Preterm Labor: Women who experience preterm labor are at a higher risk, particularly if they have other risk factors present[12].

Conclusion

Chorioamnionitis is a serious condition that requires prompt recognition and management to prevent complications for both the mother and the newborn. Clinicians should be aware of the clinical signs and symptoms, as well as the patient characteristics that may predispose individuals to this infection. Early intervention can significantly improve outcomes, making awareness and understanding of this condition essential in obstetric care.

For further management and treatment protocols, healthcare providers should refer to established clinical guidelines and consider the individual patient's circumstances.

Approximate Synonyms

Chorioamnionitis, classified under the ICD-10-CM code O41.12, refers to an infection of the fetal membranes (chorion and amnion) that can occur during pregnancy. Understanding alternative names and related terms for this condition is essential for accurate diagnosis, treatment, and documentation in medical records. Below is a detailed overview of the alternative names and related terms associated with chorioamnionitis.

Alternative Names for Chorioamnionitis

  1. Intra-amniotic Infection: This term emphasizes the infection occurring within the amniotic cavity, which is a critical aspect of chorioamnionitis.

  2. Chorioamnionitis Infection: A straightforward variation that highlights the infectious nature of the condition.

  3. Fetal Membrane Infection: This term refers to the infection affecting the membranes surrounding the fetus, which is central to the definition of chorioamnionitis.

  4. Amniotic Infection: A more general term that can refer to any infection involving the amniotic fluid or membranes.

  5. Chorioamnionitis with Maternal Fever: This term is often used in clinical settings to specify cases where the mother exhibits fever, which is a common symptom associated with the condition.

  1. Preterm Premature Rupture of Membranes (PPROM): This condition is often associated with chorioamnionitis, as the rupture of membranes can lead to infection.

  2. Intrapartum Fever: This term refers to fever occurring during labor, which can be a sign of chorioamnionitis.

  3. Sepsis: In severe cases, chorioamnionitis can lead to maternal or neonatal sepsis, a life-threatening condition caused by the body's response to infection.

  4. Endometritis: While distinct, this term refers to the inflammation of the endometrium and can occur as a complication following chorioamnionitis.

  5. Neonatal Infection: Infants born to mothers with chorioamnionitis are at increased risk for infections, making this term relevant in discussions about potential outcomes.

  6. Bacterial Vaginosis: This condition can be a risk factor for developing chorioamnionitis, as it involves an imbalance of bacteria in the vagina.

  7. Amniotic Fluid Infection: This term is often used interchangeably with chorioamnionitis, focusing on the infection of the fluid surrounding the fetus.

Conclusion

Chorioamnionitis (ICD-10 code O41.12) is a significant condition in obstetrics, and understanding its alternative names and related terms is crucial for healthcare professionals. These terms not only aid in accurate diagnosis and treatment but also enhance communication among medical staff and improve patient care. Recognizing the various terminologies associated with chorioamnionitis can facilitate better understanding and management of this condition in clinical practice.

Treatment Guidelines

Chorioamnionitis, classified under ICD-10 code O41.12, refers to an infection of the fetal membranes (chorion and amnion) that can occur during pregnancy. This condition is significant due to its potential complications for both the mother and the fetus, including preterm labor, neonatal sepsis, and increased maternal morbidity. Understanding the standard treatment approaches for chorioamnionitis is crucial for effective management and improved outcomes.

Diagnosis of Chorioamnionitis

Before discussing treatment, it is essential to understand how chorioamnionitis is diagnosed. The diagnosis typically involves:

  • Clinical Criteria: The presence of maternal fever (≥ 38°C or 100.4°F) along with one or more of the following:
  • Fetal tachycardia (heart rate > 160 beats per minute)
  • Maternal tachycardia (heart rate > 100 beats per minute)
  • Uterine tenderness
  • Foul-smelling amniotic fluid
  • Laboratory Tests: Blood tests may show elevated white blood cell counts, indicating infection.

Standard Treatment Approaches

1. Antibiotic Therapy

The cornerstone of treatment for chorioamnionitis is the administration of broad-spectrum antibiotics. The typical regimen includes:

  • Initial Antibiotics: Commonly used antibiotics include:
  • Ampicillin combined with Gentamicin
  • Clindamycin may be added if there is a concern for anaerobic bacteria.

The choice of antibiotics may vary based on local guidelines and the patient's specific clinical situation. Treatment usually continues for at least 24 hours after delivery if the mother remains febrile or if there are signs of ongoing infection[1][2].

2. Delivery Management

  • Timing of Delivery: If chorioamnionitis is diagnosed, delivery is often recommended, especially if the patient is at term or if there are signs of fetal distress. The mode of delivery (vaginal or cesarean) will depend on the clinical scenario and obstetric considerations.
  • Monitoring: Continuous fetal monitoring is essential during labor to assess fetal well-being and detect any signs of distress.

3. Supportive Care

  • Fluid Management: Intravenous fluids may be administered to maintain hydration, especially if the mother is febrile or has elevated heart rates.
  • Pain Management: Appropriate analgesia should be provided to manage discomfort during labor and delivery.

4. Postpartum Care

  • Continued Antibiotic Therapy: Post-delivery, the mother may require continued antibiotic therapy for a specified duration, particularly if there are signs of infection or if the chorioamnionitis was severe.
  • Monitoring for Complications: Both the mother and the newborn should be monitored for potential complications, including sepsis, respiratory distress, and other infections.

Conclusion

Chorioamnionitis is a serious condition that necessitates prompt diagnosis and treatment to mitigate risks to both the mother and the fetus. The standard treatment approach primarily involves the use of broad-spectrum antibiotics, timely delivery, and supportive care. Continuous monitoring and follow-up are essential to ensure the health and safety of both the mother and the newborn. As always, treatment protocols may vary based on individual patient circumstances and institutional guidelines, so healthcare providers should tailor their approach accordingly[3][4].

For further information or specific case management, consulting obstetric guidelines or infectious disease specialists may be beneficial.

Diagnostic Criteria

Chorioamnionitis, coded as O41.12 in the ICD-10-CM system, is an infection of the fetal membranes (chorion and amnion) that can pose significant risks to both the mother and the fetus. The diagnosis of chorioamnionitis is based on specific clinical criteria, which are essential for accurate coding and management. Below, we outline the key criteria used for diagnosing chorioamnionitis.

Clinical Criteria for Diagnosis

1. Maternal Fever

One of the primary indicators of chorioamnionitis is maternal fever, typically defined as a temperature of 100.4°F (38°C) or higher. This fever may indicate an underlying infection affecting the membranes surrounding the fetus.

2. Fetal Heart Rate Abnormalities

An elevated fetal heart rate (tachycardia) is another significant criterion. A fetal heart rate above 160 beats per minute can suggest fetal distress or infection, which may be associated with chorioamnionitis.

3. Maternal Tachycardia

In addition to fetal heart rate changes, maternal tachycardia (heart rate over 100 beats per minute) can also be indicative of chorioamnionitis. This response may occur as the body reacts to infection.

4. Uterine Tenderness

Physical examination may reveal uterine tenderness, which can be a sign of inflammation or infection in the membranes.

5. Foul-Smelling Amniotic Fluid

The presence of foul-smelling or purulent amniotic fluid is a critical diagnostic criterion. This odor can indicate bacterial infection and is often assessed during labor.

6. Prolonged Rupture of Membranes

A history of prolonged rupture of membranes (PROM), defined as rupture lasting more than 18 hours before delivery, increases the risk of developing chorioamnionitis. This condition allows for greater exposure to bacteria.

Laboratory and Diagnostic Tests

While the clinical criteria are paramount, laboratory tests may also support the diagnosis:

  • Blood Cultures: To identify any systemic infection.
  • Complete Blood Count (CBC): To check for signs of infection, such as elevated white blood cell counts.
  • Amniotic Fluid Analysis: In some cases, analysis of the amniotic fluid may be performed to detect infection.

Conclusion

The diagnosis of chorioamnionitis (ICD-10 code O41.12) relies on a combination of clinical signs, symptoms, and sometimes laboratory findings. Recognizing these criteria is crucial for timely intervention, as untreated chorioamnionitis can lead to serious complications for both the mother and the newborn. Proper coding and documentation of these criteria are essential for effective patient management and healthcare billing practices.

Related Information

Description

  • Inflammation of fetal membranes due to infection
  • Bacteria ascend from lower genital tract into amniotic cavity
  • Typically occurs with prolonged rupture of membranes
  • Common pathogens include Group B Streptococcus, Escherichia coli
  • Maternal fever and tachycardia in mother and fetus
  • Uterine tenderness, foul-smelling amniotic fluid, leukocytosis
  • Increased risk of postpartum infections and sepsis for mother
  • Increased risk of preterm birth, respiratory distress syndrome

Clinical Information

  • Maternal Fever: Temperature above 38°C
  • Tachycardia: Increased heart rate in mother and fetus
  • Uterine Tenderness: Inflammation of membranes
  • Foul-Smelling Amniotic Fluid: Malodorous fluid present
  • Increased Maternal Heart Rate: Response to infection
  • Nausea and Vomiting: Gastrointestinal symptoms due to infection
  • Leukocytosis: Elevated white blood cell count
  • Signs of Preterm Labor: Contractions or other signs of labor
  • Prolonged Rupture of Membranes: Increased risk after 18 hours
  • Multiple Vaginal Examinations: Introduction of bacteria
  • Internal Fetal Monitoring: Potential bacterial introduction
  • Maternal Factors: Obesity, diabetes, and previous chorioamnionitis

Approximate Synonyms

  • Intra-amniotic Infection
  • Chorioamnionitis Infection
  • Fetal Membrane Infection
  • Amniotic Infection
  • Chorioamnionitis with Maternal Fever

Treatment Guidelines

  • Administer broad-spectrum antibiotics
  • Monitor for signs of fetal distress
  • Delivery is often recommended if at term
  • Use ampicillin and gentamicin as initial therapy
  • Add clindamycin for anaerobic bacteria concern
  • Continue antibiotic therapy for 24 hours post-delivery
  • Provide supportive care with fluid management and pain control

Diagnostic Criteria

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