ICD-10: R82.994
Hypercalciuria
Clinical Information
Inclusion Terms
- Idiopathic hypercalciuria
Additional Information
Description
Hypercalciuria, denoted by the ICD-10 code R82.994, refers to the presence of an abnormally high concentration of calcium in the urine. This condition can be indicative of various underlying health issues and may lead to complications such as kidney stones or renal impairment if not addressed.
Clinical Description of Hypercalciuria
Definition and Pathophysiology
Hypercalciuria is characterized by elevated levels of calcium in the urine, typically defined as more than 300 mg of calcium excreted in a 24-hour urine collection. The condition can arise from several factors, including:
- Dietary Intake: High calcium intake from food or supplements can lead to increased urinary calcium excretion.
- Metabolic Disorders: Conditions such as hyperparathyroidism, certain malignancies, and vitamin D disorders can cause increased calcium levels in the blood, subsequently leading to hypercalciuria.
- Renal Tubular Dysfunction: Impaired renal tubular reabsorption of calcium can result in excessive calcium loss in urine.
Symptoms and Complications
Many individuals with hypercalciuria may be asymptomatic; however, some may experience symptoms related to kidney stones, such as:
- Severe flank pain
- Hematuria (blood in urine)
- Frequent urination
- Nausea and vomiting
If left untreated, hypercalciuria can lead to the formation of calcium-based kidney stones, which can cause significant pain and may require surgical intervention.
Diagnosis
Diagnosis of hypercalciuria typically involves:
- Urine Tests: A 24-hour urine collection is the standard method to measure calcium levels. A calcium level exceeding 300 mg per day is indicative of hypercalciuria.
- Blood Tests: Serum calcium and parathyroid hormone (PTH) levels are often measured to identify potential underlying causes.
- Imaging Studies: In cases of kidney stones, imaging studies such as ultrasound or CT scans may be performed to assess the kidneys and urinary tract.
Treatment
Management of hypercalciuria focuses on addressing the underlying cause and may include:
- Dietary Modifications: Reducing dietary calcium and sodium intake can help lower urinary calcium levels.
- Medications: Thiazide diuretics may be prescribed to reduce calcium excretion in urine.
- Hydration: Increasing fluid intake can help dilute urine and reduce the risk of stone formation.
Conclusion
ICD-10 code R82.994 for hypercalciuria encapsulates a condition that can have significant implications for renal health. Early diagnosis and appropriate management are crucial to prevent complications such as kidney stones and to address any underlying metabolic disorders. Regular monitoring and lifestyle adjustments can play a vital role in managing this condition effectively.
Clinical Information
Hypercalciuria, denoted by the ICD-10-CM code R82.994, refers to the presence of an abnormally high concentration of calcium in the urine. This condition can be indicative of various underlying health issues and may lead to significant clinical implications if not addressed. Below is a detailed overview of the clinical presentation, signs, symptoms, and patient characteristics associated with hypercalciuria.
Clinical Presentation
Definition and Causes
Hypercalciuria is characterized by elevated levels of calcium in the urine, which can result from several factors, including:
- Dietary Intake: High calcium intake from food or supplements.
- Metabolic Disorders: Conditions such as hyperparathyroidism, certain malignancies, or renal tubular acidosis.
- Genetic Factors: Familial hypercalciuria can predispose individuals to this condition.
- Dehydration: Insufficient fluid intake can concentrate urine calcium levels.
Symptoms
Many patients with hypercalciuria may be asymptomatic; however, when symptoms do occur, they can include:
- Kidney Stones: The most common complication, leading to severe flank pain, hematuria (blood in urine), and urinary obstruction.
- Frequent Urination: Increased urination may occur due to the body's attempt to excrete excess calcium.
- Abdominal Pain: Discomfort may arise from kidney stones or other related complications.
- Nausea and Vomiting: These symptoms can occur, particularly if kidney stones are present.
Signs
Physical Examination
During a physical examination, healthcare providers may observe:
- Flank Tenderness: Pain upon palpation of the kidney area, indicating possible kidney stones.
- Signs of Dehydration: Such as dry mucous membranes or decreased skin turgor, especially in cases where dehydration is a contributing factor.
Laboratory Findings
Diagnostic tests may reveal:
- Urine Calcium Levels: A 24-hour urine collection is often performed to measure calcium excretion.
- Blood Tests: To assess serum calcium, parathyroid hormone levels, and renal function, which can help identify underlying causes.
Patient Characteristics
Demographics
Hypercalciuria can affect individuals across various demographics, but certain characteristics may be more prevalent:
- Age: It can occur in both children and adults, with varying causes. In children, it may be linked to dietary habits, while in adults, it is often associated with metabolic disorders.
- Gender: Males may be more frequently affected by kidney stones, which are a common complication of hypercalciuria.
Risk Factors
Several risk factors can increase the likelihood of developing hypercalciuria:
- Family History: A genetic predisposition can play a significant role.
- Diet: High intake of calcium-rich foods or supplements.
- Dehydration: Inadequate fluid intake, particularly in hot climates or during vigorous exercise.
Conclusion
Hypercalciuria, represented by the ICD-10-CM code R82.994, is a condition that can lead to significant health issues, particularly kidney stones. While many patients may remain asymptomatic, those who do exhibit symptoms often experience discomfort and complications that necessitate medical evaluation. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with hypercalciuria is crucial for timely diagnosis and management. If you suspect hypercalciuria or experience related symptoms, consulting a healthcare provider for appropriate testing and treatment is essential.
Approximate Synonyms
Hypercalciuria, denoted by the ICD-10-CM code R82.994, refers to the presence of excessive calcium in the urine. This condition can be associated with various underlying health issues and may lead to complications such as kidney stones. Understanding alternative names and related terms can enhance clarity in medical documentation and communication.
Alternative Names for Hypercalciuria
- Calcium Nephrolithiasis: This term is often used when hypercalciuria leads to the formation of calcium-based kidney stones.
- Calcium Excess in Urine: A straightforward description that indicates the primary issue of elevated calcium levels in urine.
- Hypercalcemia: While hypercalcemia refers to high calcium levels in the blood, it is often related to hypercalciuria, as elevated blood calcium can lead to increased urinary calcium excretion.
- Calciuria: A more general term that refers to the presence of calcium in urine, which can be either normal or excessive.
Related Terms and Conditions
- Kidney Stones: Often a direct consequence of hypercalciuria, particularly calcium oxalate stones.
- Primary Hyperparathyroidism: A condition that can cause hypercalciuria due to increased parathyroid hormone levels, leading to elevated calcium in the blood and urine.
- Renal Tubular Acidosis: A disorder that can result in hypercalciuria due to impaired renal tubular function.
- Malabsorption Syndromes: Conditions like celiac disease or Crohn's disease can lead to hypercalciuria due to altered calcium absorption.
- Hypervitaminosis D: Excessive vitamin D can increase calcium absorption from the gut, potentially leading to hypercalciuria.
Clinical Context
Hypercalciuria is often evaluated in the context of urinary abnormalities, and it may be coded alongside other conditions that affect calcium metabolism or renal function. The ICD-10 code R82.994 is part of a broader category of abnormal findings in urine, which includes other codes such as R82.998 for other abnormal findings in urine[1][2].
Understanding these alternative names and related terms is crucial for healthcare professionals when diagnosing, documenting, and treating conditions associated with hypercalciuria. This knowledge aids in ensuring accurate coding and effective communication among medical teams.
Diagnostic Criteria
Hypercalciuria, denoted by the ICD-10-CM code R82.994, refers to the presence of an abnormally high level of calcium in the urine. This condition can be indicative of various underlying health issues, including metabolic disorders, kidney stones, or parathyroid gland abnormalities. The diagnosis of hypercalciuria typically involves several criteria and diagnostic steps, which are outlined below.
Diagnostic Criteria for Hypercalciuria
1. Clinical Symptoms and History
- Patient Symptoms: Patients may present with symptoms such as frequent urination, abdominal pain, or kidney stones. A thorough medical history is essential to identify any previous occurrences of kidney stones or related conditions.
- Family History: A family history of kidney stones or metabolic disorders can also be relevant, as hypercalciuria can have a genetic component.
2. Laboratory Tests
- 24-Hour Urine Collection: The primary diagnostic test for hypercalciuria is a 24-hour urine collection to measure the total amount of calcium excreted. A calcium excretion level greater than 300 mg per day in adults is typically considered indicative of hypercalciuria.
- Serum Calcium Levels: Blood tests to measure serum calcium levels are also performed. Elevated serum calcium levels may suggest primary hyperparathyroidism or other metabolic disorders.
- Additional Urine Tests: Other urine tests may be conducted to assess for the presence of other abnormalities, such as phosphate or oxalate levels, which can help in determining the underlying cause of hypercalciuria.
3. Imaging Studies
- Ultrasound or CT Scan: Imaging studies may be utilized to check for kidney stones or other structural abnormalities in the urinary tract. These studies can help rule out obstructive causes of hypercalciuria.
4. Differential Diagnosis
- Exclusion of Other Conditions: It is crucial to differentiate hypercalciuria from other conditions that may cause similar symptoms or laboratory findings. Conditions such as hyperparathyroidism, malignancies, or certain medications can lead to increased calcium levels in urine.
5. Follow-Up and Monitoring
- Regular Monitoring: Once diagnosed, patients may require regular monitoring of calcium levels in urine and blood to manage and treat any underlying conditions effectively.
Conclusion
The diagnosis of hypercalciuria (ICD-10 code R82.994) involves a combination of clinical evaluation, laboratory testing, and imaging studies to confirm elevated calcium levels in urine and to identify any underlying causes. Proper diagnosis is essential for effective management and treatment of the condition, which may include dietary modifications, medications, or further investigation into potential metabolic disorders. Regular follow-up is also important to monitor the patient's condition and adjust treatment as necessary.
Treatment Guidelines
Hypercalciuria, denoted by the ICD-10 code R82.994, refers to the condition characterized by an excessive amount of calcium in the urine. This condition can lead to various complications, including kidney stones and renal impairment. The management of hypercalciuria typically involves a combination of dietary modifications, pharmacological interventions, and addressing any underlying conditions contributing to the elevated calcium levels. Below is a detailed overview of standard treatment approaches for hypercalciuria.
Dietary Modifications
1. Fluid Intake
Increasing fluid intake is crucial for patients with hypercalciuria. Adequate hydration helps dilute urine and reduces the concentration of calcium, thereby minimizing the risk of stone formation. Patients are often advised to drink at least 2 to 3 liters of water daily, unless contraindicated by other medical conditions.
2. Calcium Intake
While it may seem counterintuitive, dietary calcium should not be excessively restricted. A moderate intake of calcium (around 800-1200 mg per day) is recommended, as low calcium diets can lead to increased intestinal absorption of oxalate, potentially worsening hypercalciuria. Foods rich in calcium include dairy products, leafy greens, and fortified foods.
3. Oxalate and Sodium Reduction
Reducing dietary oxalate (found in foods like spinach, nuts, and chocolate) and sodium can also be beneficial. High sodium intake can increase calcium excretion in urine, so a low-sodium diet is often recommended.
Pharmacological Interventions
1. Thiazide Diuretics
Thiazide diuretics, such as hydrochlorothiazide, are commonly prescribed for patients with hypercalciuria. These medications help reduce urinary calcium excretion by promoting calcium reabsorption in the kidneys. This approach is particularly effective in patients who have a history of calcium stone formation.
2. Potassium Citrate
Potassium citrate can be used to alkalinize the urine, which may help prevent the formation of calcium stones. It also helps to increase urinary citrate levels, which inhibit stone formation.
3. Bisphosphonates
In cases where hypercalciuria is associated with conditions like hyperparathyroidism or malignancy, bisphosphonates may be indicated to lower serum calcium levels.
Addressing Underlying Conditions
1. Hyperparathyroidism
If hypercalciuria is due to primary hyperparathyroidism, surgical intervention to remove the overactive parathyroid gland may be necessary.
2. Malignancy
In cases where hypercalciuria is secondary to malignancy, treating the underlying cancer can help normalize calcium levels.
Monitoring and Follow-Up
Regular follow-up appointments are essential for monitoring calcium levels in urine and serum, as well as assessing kidney function. Patients may undergo periodic imaging studies to check for the presence of kidney stones or other complications.
Conclusion
The management of hypercalciuria (ICD-10 code R82.994) involves a multifaceted approach that includes dietary changes, pharmacological treatments, and addressing any underlying health issues. By implementing these strategies, healthcare providers can help patients effectively manage their condition and reduce the risk of complications such as kidney stones. Regular monitoring and adjustments to the treatment plan are crucial for optimal outcomes.
Related Information
Description
- Hypocalcemia not present
- Elevated urine calcium levels
- Dietary high in calcium causes issue
- Metabolic disorders cause elevated calcium
- Kidney stones formed from excess calcium
- Symptoms include flank pain and hematuria
- Urine tests measure calcium levels over 24 hours
- Blood tests check for underlying causes
- Imaging studies assess kidney and urinary tract
- Dietary modifications to reduce calcium intake
- Medications like thiazide diuretics prescribed
- Increased hydration reduces risk of stones
Clinical Information
- High calcium levels in urine
- Elevated calcium from diet or supplements
- Metabolic disorders cause hypercalciuria
- Genetic factors contribute to condition
- Dehydration concentrates calcium in urine
- Kidney stones are common complication
- Frequent urination is possible symptom
- Abdominal pain due to kidney stones
- Nausea and vomiting can occur
- Flank tenderness on physical exam
- Signs of dehydration noted
- Urine calcium levels measured in lab tests
- Blood tests assess serum calcium and renal function
Approximate Synonyms
- C Calcium Nephrolithiasis
- C Calcium Excess in Urine
- H Hypercalcemia
- C Calciuria
- Kidney Stones
- P Primary Hyperparathyroidism
- R Renal Tubular Acidosis
- M Malabsorption Syndromes
- H Hypervitaminosis D
Diagnostic Criteria
- Frequent urination in patients
- Abdominal pain symptoms present
- Kidney stones occurrence history
- Family history of kidney stones
- 24-hour urine collection for calcium
- Calcium excretion >300 mg/day in adults
- Elevated serum calcium levels
- Blood tests for serum calcium levels
- Additional urine tests for phosphate/oxalate
- Ultrasound or CT scan imaging studies
- Exclusion of other conditions
- Regular monitoring of calcium levels
Treatment Guidelines
- Increase fluid intake to 2-3 liters daily
- Moderate calcium intake (800-1200 mg/day)
- Reduce dietary oxalate and sodium intake
- Prescribe thiazide diuretics for urinary calcium excretion reduction
- Use potassium citrate for urine alkalinization and stone prevention
- Bisphosphonates for lowering serum calcium levels in malignancy/hyperparathyroidism
- Monitor calcium levels, kidney function, and check for stones
Related Diseases
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