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Loperamide

CHEBI:CHEBI_6532

Definition

A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Chemical Information

Molecular Formula
C29H33ClN2O2
Molecular Mass
477.03800
Charge
0
SMILES
CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1
InChI
InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3
InChIKey
RDOIQAHITMMDAJ-UHFFFAOYSA-N

Alternative Names

  • 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
  • loperamida
  • loperamide
  • loperamide
  • Loperamide
  • loperamidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6468
oboInOwl#hasDbXref
Wikipedia:Loperamide
core#notation
CHEBI:6532

Additional References

Wikipedia:Loperamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6468
oboInOwl#hasDbXref
Wikipedia:Loperamide
oboInOwl#id
CHEBI:6532
generic_name
loperamide hcl
brand_name
Anti-Diarrheal, CVP HEALTH
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_55322
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000037
product_ndc
75907-097
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_86969
brand_name_base
Anti-Diarrheal, CVP HEALTH
labeler_name
Fred's Inc.
application_number
ANDA218122
listing_expiration_date
20241231
spl_id
cefb1fd9-768f-c7a4-b9b1-ab7faaa67308
marketing_start_date
20000327
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
CAPSULE, LIQUID FILLED
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113436
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31296
package_description
2 BLISTER PACK in 1 CARTON (75907-097-24) / 12 CAPSULE, LIQUID FILLED in 1 BLISTER PACK
package_ndc
58602-815-75
route
ORAL
package_marketing_start_date
20180611
rxcui
1250693
unii
92RU3N3Y1O
spl_set_id
356d9432-d948-4b88-b297-9161b845f86b
manufacturer_name
CARDINAL HEALTH
has_treatment
http://purl.obolibrary.org/obo/DOID_4412
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_86969
owl#annotatedSource
t269607
owl#someValuesFrom
t1049841
core#notation
CHEBI:6532
pharm_class
Skin Barrier Activity [PE]
active_ingredient_strength
1 mg/7.5mL
active_ingredient_name
DIMETHICONE
nui
N0000010282
pharm_class_pe
Skin Barrier Activity [PE]
upc
0355289315155
brand_name_suffix
A-D
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class