ICD-10: A02.25

Salmonella pyelonephritis

Clinical Information

Inclusion Terms

  • Salmonella tubulo-interstitial nephropathy

Additional Information

Clinical Information

Salmonella pyelonephritis, classified under ICD-10 code A02.25, is a specific type of kidney infection caused by Salmonella bacteria. Understanding its clinical presentation, signs, symptoms, and patient characteristics is crucial for effective diagnosis and management.

Clinical Presentation

Overview

Salmonella pyelonephritis typically arises from a urinary tract infection (UTI) that ascends to the kidneys. It is often associated with underlying conditions that predispose individuals to infections, such as urinary tract abnormalities or immunocompromised states.

Signs and Symptoms

Patients with Salmonella pyelonephritis may exhibit a range of symptoms, which can vary in severity:

  • Fever: Often a prominent symptom, indicating an infectious process.
  • Chills: Accompanying fever, patients may experience chills.
  • Flank Pain: Pain in the lower back or side, particularly on the affected side, is common.
  • Dysuria: Painful urination may occur, reflecting irritation of the urinary tract.
  • Increased Urinary Frequency and Urgency: Patients may feel the need to urinate more often and urgently.
  • Nausea and Vomiting: Gastrointestinal symptoms can accompany the infection.
  • Hematuria: Blood in the urine may be present, indicating irritation or damage to the urinary tract.
  • General Malaise: Patients often report feeling unwell or fatigued.

Patient Characteristics

Certain patient demographics and characteristics are associated with a higher risk of developing Salmonella pyelonephritis:

  • Age: While it can occur at any age, young children and older adults are at higher risk due to potential underlying health issues.
  • Gender: Females are generally more susceptible to urinary tract infections, which can lead to pyelonephritis.
  • Underlying Conditions: Patients with diabetes, structural abnormalities of the urinary tract, or those who are immunocompromised (e.g., due to HIV/AIDS, cancer treatments) are at increased risk.
  • Recent Antibiotic Use: Prior antibiotic therapy can disrupt normal flora and predispose individuals to infections by resistant strains of Salmonella.
  • Travel History: Exposure to contaminated food or water, particularly in endemic areas, can increase the risk of Salmonella infections.

Conclusion

Salmonella pyelonephritis is a serious condition that requires prompt recognition and treatment. The clinical presentation typically includes fever, flank pain, and urinary symptoms, with certain patient characteristics heightening the risk of infection. Early diagnosis and appropriate management are essential to prevent complications associated with this infection, particularly in vulnerable populations. Understanding these aspects can aid healthcare providers in identifying and treating affected patients effectively.

Approximate Synonyms

Salmonella pyelonephritis, classified under the ICD-10-CM code A02.25, refers to a specific type of kidney infection caused by Salmonella bacteria. Understanding alternative names and related terms can enhance clarity in medical documentation and communication. Below are some alternative names and related terms associated with this condition.

Alternative Names for Salmonella Pyelonephritis

  1. Salmonella Kidney Infection: This term directly describes the infection's location and causative agent.
  2. Salmonella Renal Infection: Similar to the above, this term emphasizes the renal (kidney) aspect of the infection.
  3. Salmonella Nephritis: While nephritis generally refers to inflammation of the kidneys, it can be used to describe infections caused by Salmonella.
  4. Salmonella Urinary Tract Infection (UTI): Although more general, this term can sometimes encompass pyelonephritis when the infection ascends from the lower urinary tract to the kidneys.
  1. Localized Salmonella Infections (A02.2): This broader category includes various localized infections caused by Salmonella, which may also involve the kidneys.
  2. Renal Tubulo-Interstitial Diseases (N10-N16): This classification includes diseases affecting the renal tubules and interstitium, which can be relevant in the context of pyelonephritis.
  3. Salmonellosis: This is the general term for infections caused by Salmonella, which can manifest in various forms, including gastrointestinal and systemic infections.
  4. Acute Pyelonephritis: While not specific to Salmonella, this term describes a sudden kidney infection that can be caused by various pathogens, including Salmonella.

Conclusion

Understanding the alternative names and related terms for Salmonella pyelonephritis (ICD-10 code A02.25) is crucial for accurate diagnosis, treatment, and documentation in medical settings. These terms help healthcare professionals communicate effectively about the condition and ensure appropriate care for affected patients. If you need further information or specific details about treatment or management, feel free to ask!

Diagnostic Criteria

Salmonella pyelonephritis, classified under ICD-10 code A02.25, is a specific type of kidney infection caused by Salmonella bacteria. The diagnosis of this condition involves several criteria, which can be categorized into clinical, laboratory, and imaging findings.

Clinical Criteria

  1. Symptoms: Patients typically present with symptoms indicative of a urinary tract infection (UTI) and pyelonephritis, which may include:
    - Fever and chills
    - Flank pain or lower back pain
    - Nausea and vomiting
    - Dysuria (painful urination)
    - Increased frequency and urgency of urination

  2. History of Exposure: A history of exposure to Salmonella, such as through contaminated food or water, can support the diagnosis. This is particularly relevant in cases where gastrointestinal symptoms precede the urinary symptoms.

Laboratory Criteria

  1. Urine Culture: The definitive diagnosis of Salmonella pyelonephritis is made through urine culture, which should yield Salmonella species. This is critical as it differentiates it from other causes of pyelonephritis.

  2. Blood Cultures: In severe cases, blood cultures may also be performed to detect the presence of Salmonella in the bloodstream, indicating a more systemic infection.

  3. Urinalysis: A urinalysis may show signs of infection, such as:
    - Presence of white blood cells (WBCs)
    - Bacteria
    - Nitrites (if present, indicating gram-negative bacteria)
    - Hematuria (blood in urine)

Imaging Studies

  1. Ultrasound or CT Scan: Imaging studies may be utilized to assess for complications of pyelonephritis, such as abscess formation or obstruction of the urinary tract. These studies can help visualize the kidneys and urinary tract to rule out other conditions.

Conclusion

In summary, the diagnosis of Salmonella pyelonephritis (ICD-10 code A02.25) relies on a combination of clinical symptoms, laboratory findings (especially urine and blood cultures), and imaging studies when necessary. Accurate diagnosis is crucial for effective treatment, which typically involves appropriate antibiotic therapy targeting Salmonella species. If you have further questions or need more specific details, feel free to ask!

Treatment Guidelines

Salmonella pyelonephritis, classified under ICD-10 code A02.25, is a serious infection that occurs when Salmonella bacteria infect the kidneys. This condition can lead to significant morbidity if not treated appropriately. Below, we explore the standard treatment approaches for this condition, including diagnosis, antibiotic therapy, and supportive care.

Diagnosis of Salmonella Pyelonephritis

Before initiating treatment, accurate diagnosis is crucial. The diagnosis typically involves:

  • Clinical Evaluation: Patients often present with symptoms such as fever, flank pain, dysuria, and changes in urinary habits.
  • Laboratory Tests: Urinalysis may reveal pyuria, hematuria, and bacteriuria. Urine cultures are essential for identifying Salmonella species and determining antibiotic sensitivity.
  • Imaging Studies: Ultrasound or CT scans may be performed to assess for complications such as abscess formation or obstruction in the urinary tract[1].

Standard Treatment Approaches

1. Antibiotic Therapy

Antibiotic treatment is the cornerstone of managing Salmonella pyelonephritis. The choice of antibiotics is guided by culture results and local resistance patterns. Commonly used antibiotics include:

  • Ciprofloxacin: Often the first-line treatment due to its effectiveness against Salmonella.
  • Ceftriaxone: A third-generation cephalosporin that may be used, especially in severe cases or when oral therapy is not feasible.
  • Azithromycin: Sometimes considered, particularly in cases where resistance to fluoroquinolones is noted.

The duration of antibiotic therapy typically ranges from 7 to 14 days, depending on the severity of the infection and the patient's clinical response[2][3].

2. Supportive Care

Supportive care is essential in managing symptoms and preventing complications:

  • Hydration: Ensuring adequate fluid intake is critical to help flush out the bacteria and prevent dehydration, especially if the patient has fever or is experiencing vomiting.
  • Pain Management: Analgesics may be prescribed to alleviate discomfort associated with flank pain or urinary symptoms.
  • Monitoring: Close monitoring of renal function and overall clinical status is necessary, particularly in hospitalized patients, to detect any deterioration early[4].

3. Management of Complications

In some cases, complications such as abscess formation or urinary obstruction may arise. These situations may require:

  • Surgical Intervention: Procedures such as drainage of abscesses or correction of anatomical abnormalities may be necessary.
  • Urological Consultation: Referral to a urologist may be warranted for persistent or complicated cases[5].

Conclusion

Salmonella pyelonephritis is a serious condition that requires prompt diagnosis and treatment. The standard approach involves targeted antibiotic therapy based on culture results, supportive care to manage symptoms, and vigilant monitoring for complications. Early intervention is key to improving outcomes and preventing long-term renal damage. If you suspect Salmonella pyelonephritis, it is crucial to seek medical attention promptly to initiate appropriate treatment.

Description

Salmonella pyelonephritis is a specific type of kidney infection caused by Salmonella bacteria, which are primarily known for causing gastrointestinal illnesses. This condition is classified under the ICD-10 code A02.25, which falls within the broader category of non-typhoidal Salmonella infections.

Clinical Description

Overview of Salmonella Infections

Salmonella is a genus of bacteria that can lead to various infections, most commonly associated with foodborne illnesses. While many infections are gastrointestinal in nature, Salmonella can also cause systemic infections, including those affecting the urinary tract and kidneys. Pyelonephritis refers to an infection of the kidney, which can result from bacteria ascending from the lower urinary tract or through the bloodstream.

Pathophysiology

In the case of Salmonella pyelonephritis, the bacteria can enter the urinary tract and ascend to the kidneys, leading to inflammation and infection. This condition may occur in individuals with underlying health issues, such as urinary tract abnormalities, immunocompromised states, or those who have recently experienced gastrointestinal infections caused by Salmonella.

Symptoms

Patients with Salmonella pyelonephritis may present with a range of symptoms, including:
- Fever: Often a sign of systemic infection.
- Flank Pain: Pain in the side or back, typically on the affected side.
- Dysuria: Painful urination.
- Increased Urinary Frequency: A need to urinate more often than usual.
- Nausea and Vomiting: Common in systemic infections.
- Chills: Accompanying fever.

Diagnosis

Diagnosis typically involves:
- Urinalysis: To detect the presence of bacteria, white blood cells, and other indicators of infection.
- Urine Culture: Specifically to identify Salmonella as the causative agent.
- Blood Tests: To assess for systemic infection and kidney function.
- Imaging Studies: Such as ultrasound or CT scans, may be used to evaluate the kidneys and urinary tract for complications.

Treatment

The treatment of Salmonella pyelonephritis generally involves:
- Antibiotics: The choice of antibiotic may depend on the sensitivity of the Salmonella strain identified in cultures. Commonly used antibiotics include fluoroquinolones or cephalosporins.
- Supportive Care: This may include hydration and pain management.
- Monitoring: Close observation for potential complications, such as abscess formation or sepsis.

Conclusion

Salmonella pyelonephritis, classified under ICD-10 code A02.25, represents a serious infection that requires prompt diagnosis and treatment. Understanding the clinical presentation, diagnostic methods, and treatment options is crucial for effective management of this condition. If you suspect a case of Salmonella pyelonephritis, it is essential to seek medical attention for appropriate evaluation and care.

Related Information

Clinical Information

  • Fever is often a prominent symptom
  • Chills accompany fever in many cases
  • Flank pain occurs on the affected side
  • Dysuria indicates urinary tract irritation
  • Increased frequency and urgency occur
  • Nausea and vomiting can accompany infection
  • Hematuria indicates damage to the urinary tract
  • General malaise is a common symptom in patients
  • Young children are at higher risk of infection
  • Older adults are more susceptible due to health issues
  • Females are generally more prone to UTIs
  • Underlying conditions increase risk significantly
  • Recent antibiotic use can disrupt normal flora
  • Travel history increases exposure to contamination

Approximate Synonyms

  • Salmonella Kidney Infection
  • Salmonella Renal Infection
  • Salmonella Nephritis
  • Salmonella UTI
  • Localized Salmonella Infections
  • Renal Tubulo-Interstitial Diseases
  • Salmonellosis
  • Acute Pyelonephritis

Diagnostic Criteria

  • Fever and chills
  • Flank pain or lower back pain
  • Nausea and vomiting
  • Dysuria (painful urination)
  • Increased frequency and urgency of urination
  • Urine culture positive for Salmonella
  • Blood cultures positive for Salmonella
  • Presence of WBCs in urine
  • Bacteria present in urine
  • Nitrites present in urine
  • Hematuria (blood in urine)
  • Abscess formation or urinary tract obstruction

Treatment Guidelines

  • Accurate diagnosis through clinical evaluation
  • Laboratory tests including urinalysis and urine cultures
  • Imaging studies such as ultrasound or CT scans
  • Ciprofloxacin as first-line antibiotic therapy
  • Ceftriaxone for severe cases or oral therapy not feasible
  • Azithromycin in cases with fluoroquinolone resistance
  • 7-14 days of antibiotic therapy duration
  • Hydration to prevent dehydration and flush bacteria
  • Pain management with analgesics
  • Close monitoring of renal function and clinical status
  • Surgical intervention for abscess formation or obstruction

Description

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